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Gene

GDF6

growth differentiation factor 6

Summary

Cytogenetic location
8q22.1
Coordinates
Chromosome 8: 96,142,333–96,160,806 (GRCh38)
Exons
2 exons across 18.5 kb
Protein
455 amino acids
Also known as
BMP13, KFS, KFS1
Previous symbols
SGM1
MANE Select transcript
ENST00000287020.7NM_001001557.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GDF6 yet. The test sequences your whole genome, so your data includes it all the same.

How GDF6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 8, with a bracket where GDF6 sits. GDF6 and 5 genes near it on chromosome 8, from 95,651,570 to 96,651,569.Chromosome 88q22.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.395.8 Mb96 Mb96.2 Mb96.4 Mb96.6 MbGDF6: 96,142,333–96,160,806, reverse strandGDF6UQCRB: 96,222,947–96,235,621, reverse strandUQCRBMTERF3: 96,238,162–96,261,626, reverse strandMTERF3PTDSS1: 96,261,885–96,386,078, forward strandPTDSS1SDC2: 96,493,410–96,613,465, forward strandSDC2CPQ: 96,644,982–97,152,036, forward strandCPQDiagram of GDF6: 2 exons on the reverse strand of chromosome 8Exon 2: 2 known disease-causing sitesExon 2: 96,142,333–96,145,524, 3,192 basesExon 1: 96,160,287–96,160,806, 520 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 18.5 kb; 1,368 of those bases code for the protein.

How a genome test reads GDF6

2

positions in GDF6 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 18.5 kb of GDF6, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GDF6 gene: growth differentiation factor 6. Retrieved 17 October 2026, from https://dantelabs.com/genes/gdf6

Vancouver

Dante Labs. GDF6 gene: growth differentiation factor 6 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gdf6

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