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Gene

PRRX1

paired related homeobox 1

Summary

Cytogenetic location
1q24.2
Coordinates
Chromosome 1: 170,664,131–170,739,421 (GRCh38)
Exons
4 exons across 75.3 kb
Protein
245 amino acids
Also known as
PHOX1
Previous symbols
PMX1
MANE Select transcript
ENST00000239461.11NM_022716.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PRRX1 yet. The test sequences your whole genome, so your data includes it all the same.

How PRRX1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where PRRX1 sits. PRRX1 and 4 genes near it on chromosome 1, from 170,201,776 to 171,201,775.Chromosome 11q24.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44170.4 Mb170.6 Mb170.8 Mb171 Mb171.2 MbGORAB: 170,531,819–170,553,834, forward strandGORABPRRX1: 170,664,131–170,739,421, forward strandPRRX1MROH9: 170,935,429–171,064,765, forward strandMROH9FMO3: 171,085,113–171,118,675, forward strandFMO3FMO2: 171,185,249–171,212,686, forward strandFMO2Diagram of PRRX1: 4 exons on the forward strand of chromosome 1Exon 1: 170,664,131–170,664,459, 329 basesExon 2: 170,719,726–170,719,901, 176 basesExon 3: 170,726,220–170,726,401, 182 basesExon 4: 170,736,048–170,739,421, 3,374 bases12345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.1 kb of the gene's 75.3 kb; 738 of those bases code for the protein.

Sequencing PRRX1

2Easy

How hard PRRX1 is to sequence with short reads, out of 100

Almost all of PRRX1's exons sit where short reads map cleanly.

What adds to it: the share of PRRX1's exons in each kind of hard region

  • Mappability0%
  • Homology0%
  • Repeats6.6%
  • GC content8.1%
  • Reference coverage0%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

Traits linked to PRRX1

The Human Phenotype Ontology lists these as features of the rare conditions PRRX1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). PRRX1 gene: paired related homeobox 1. Retrieved 18 October 2026, from https://dantelabs.com/genes/prrx1

Vancouver

Dante Labs. PRRX1 gene: paired related homeobox 1 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/prrx1

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