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Gene

ELMO2

engulfment and cell motility 2

Summary

Cytogenetic location
20q13.12
Coordinates
Chromosome 20: 46,366,050–46,406,615 (GRCh38)
Exons
22 exons across 40.6 kb
Protein
720 amino acids
Also known as
CED12, ELMO-2, CED-12, KIAA1834, FLJ11656
MANE Select transcript
ENST00000290246.11NM_133171.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ELMO2 yet. The test sequences your whole genome, so your data includes it all the same.

How ELMO2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 20, with a bracket where ELMO2 sits. ELMO2 and 18 genes near it on chromosome 20, from 45,886,333 to 46,886,332.Chromosome 2020q13.12p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.3346 Mb46.2 Mb46.4 Mb46.6 Mb46.8 MbSPATA25: 45,886,491–45,887,626, reverse strandNEURL2: 45,888,002–45,891,220, reverse strandNEURL2CTSA: 45,890,144–45,898,949, forward strandCTSAPLTP: 45,897,535–45,912,235, reverse strandPLTPPCIF1: 45,934,673–45,948,023, forward strandPCIF1ZNF335: 45,948,653–45,972,358, reverse strandZNF335MMP9: 46,008,869–46,016,561, forward strandMMP9SLC12A5: 46,021,675–46,060,150, forward strandSLC12A5NCOA5: 46,060,984–46,089,973, reverse strandNCOA5CD40: 46,118,240–46,130,378, forward strandCD40CDH22: 46,173,737–46,309,009, reverse strandCDH22SLC35H1: 46,345,980–46,364,460, reverse strandSLC35H1ELMO2: 46,366,050–46,406,615, reverse strandELMO2ZNF840P: 46,459,441–46,495,558, forward strandZNF840PZNF334: 46,499,630–46,513,596, reverse strandZNF334OCSTAMP: 46,540,946–46,550,654, reverse strandOCSTAMPSLC13A3: 46,557,823–46,684,467, reverse strandSLC13A3TP53RK: 46,684,344–46,689,664, reverse strandTP53RKSLC2A10: 46,709,577–46,737,312, forward strandSLC2A10Diagram of ELMO2: 22 exons on the reverse strand of chromosome 20Exon 17: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 22: 46,366,050–46,367,560, 1,511 basesExon 21: 46,368,891–46,368,968, 78 basesExon 20: 46,370,443–46,370,525, 83 basesExon 19: 46,371,352–46,371,459, 108 basesExon 18: 46,371,579–46,371,691, 113 basesExon 17: 46,371,806–46,371,969, 164 basesExon 16: 46,373,399–46,373,535, 137 basesExon 15: 46,374,332–46,374,440, 109 basesExon 14: 46,374,536–46,374,640, 105 basesExon 13: 46,375,236–46,375,370, 135 basesExon 12: 46,375,668–46,375,790, 123 basesExon 11: 46,380,253–46,380,303, 51 basesExon 10: 46,383,416–46,383,494, 79 basesExon 9: 46,386,124–46,386,275, 152 basesExon 8: 46,387,338–46,387,437, 100 basesExon 7: 46,389,039–46,389,220, 182 basesExon 6: 46,393,093–46,393,143, 51 basesExon 5: 46,393,529–46,393,601, 73 basesExon 4: 46,394,049–46,394,089, 41 basesExon 3: 46,394,405–46,394,532, 128 basesExon 2: 46,398,697–46,398,771, 75 basesExon 1: 46,406,548–46,406,615, 68 bases22201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 40.6 kb; 2,163 of those bases code for the protein.

How a genome test reads ELMO2

5

positions in ELMO2 where ClinVar classes a change as pathogenic or likely pathogenic

1 of them (20%) falls in a region short reads find hard.

  • Segmental duplications (1 site)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 40.6 kb of ELMO2, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ELMO2 gene: engulfment and cell motility 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/elmo2

Vancouver

Dante Labs. ELMO2 gene: engulfment and cell motility 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/elmo2

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