Gene
GMNN
geminin DNA replication inhibitor
- HGNC 17493↗(opens in a new tab)
- Ensembl gene ENSG00000112312↗(opens in a new tab)
- NCBI Gene 51053↗(opens in a new tab)
Summary
- Cytogenetic location
- 6p22.3
- Coordinates
- Chromosome 6: 24,774,937–24,786,099 (GRCh38)
- Exons
- 7 exons across 11.2 kb
- Protein
- 209 amino acids
- Also known as
- Gem
- MANE Select transcript
- ENST00000230056.8NM_015895.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
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No Genome Test report reads GMNN yet. The test sequences your whole genome, so your data includes it all the same.
How GMNN is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.3 kb of the gene's 11.2 kb; 630 of those bases code for the protein.
How a genome test reads GMNN
3
positions in GMNN where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 11.2 kb of GMNN, introns included, not only the 1.3 kb of exons.
Traits linked to GMNN
The Human Phenotype Ontology lists these as features of the rare conditions GMNN can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Frontal bossing
- Full lips
- Small retruded chin
- Underdeveloped tissue around nostril
- Abnormally small head
- Absence of lower jaw bones
- Little lower jaw
- Narrow mouth
Show 15 more traits
Abnormality of the ear
- Small ears
- Abnormal shape/structure of ear
- Abnormality of the outer ear
- Absent ear
- Absent ear canal
- Ears rotated toward back of head
- Low-set ears
- Hearing impairment
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). GMNN gene: geminin DNA replication inhibitor. Retrieved 17 October 2026, from https://dantelabs.com/genes/gmnn
Dante Labs. GMNN gene: geminin DNA replication inhibitor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gmnn
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