Požymis
Pins and needles feeling
Klinikinis pavadinimas: Paresthesia
Abnormal sensations such as tingling, pricking, or numbness of the skin with no apparent physical cause.
Santrauka
- Taip pat vadinama
- Tingling, Paresthesias
- Kūno sistema
- Abnormality of the nervous system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Pins and needles feeling, and the rest of your genome, with one test.
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Įsigyti savo Genome Test127 genų susiję su Pins and needles feeling
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Pins and needles feeling. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| LAMB1laminin subunit beta 1 | Visada | 1 ligoje |
| RAB32RAB32, member RAS oncogene family | Visada | 1 ligoje |
| APPamyloid beta precursor protein | Labai dažnai (80–99%) | 2 ligose |
| CALRcalreticulin | Labai dažnai (80–99%) | 1 ligoje |
| CASRcalcium sensing receptor | Labai dažnai (80–99%) | 2 ligose |
| CTDP1CTD phosphatase 1 | Labai dažnai (80–99%) | 1 ligoje |
| GNA11G protein subunit alpha 11 | Labai dažnai (80–99%) | 2 ligose |
| JAK2Janus kinase 2 | Labai dažnai (80–99%) | 3 ligose |
| LIFRLIF receptor subunit alpha | Labai dažnai (80–99%) | 1 ligoje |
| MPLMPL proto-oncogene, thrombopoietin receptor | Labai dažnai (80–99%) | 2 ligose |
| SERPING1serpin family G member 1 | Labai dažnai (80–99%) | 1 ligoje |
| SH2B3SH2B adaptor protein 3 | Labai dažnai (80–99%) | 1 ligoje |
| SLC19A2solute carrier family 19 member 2 | Labai dažnai (80–99%) | 1 ligoje |
| TET2tet methylcytosine dioxygenase 2 | Labai dažnai (80–99%) | 1 ligoje |
| TP53tumor protein p53 | Labai dažnai (80–99%) | 1 ligoje |
| AIPAHR interacting HSP90 co-chaperone | Dažnai (30–79%) | 1 ligoje |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Dažnai (30–79%) | 1 ligoje |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Dažnai (30–79%) | 2 ligose |
| CCM2CCM2 scaffold protein | Dažnai (30–79%) | 1 ligoje |
| GBE11,4-alpha-glucan branching enzyme 1 | Dažnai (30–79%) | 1 ligoje |
| GPR101G protein-coupled receptor 101 | Dažnai (30–79%) | 1 ligoje |
| KRIT1KRIT1 ankyrin repeat containing | Dažnai (30–79%) | 1 ligoje |
| KRT14keratin 14 | Dažnai (30–79%) | 1 ligoje |
| KRT5keratin 5 | Dažnai (30–79%) | 1 ligoje |
| LIG3DNA ligase 3 | Dažnai (30–79%) | 1 ligoje |
| LITAFlipopolysaccharide induced TNF factor | Dažnai (30–79%) | 1 ligoje |
| MFN2mitofusin 2 | Dažnai (30–79%) | 2 ligose |
| OPA3outer mitochondrial membrane lipid metabolism regulator OPA3 | Dažnai (30–79%) | 1 ligoje |
| PDCD10programmed cell death 10 | Dažnai (30–79%) | 1 ligoje |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Dažnai (30–79%) | 2 ligose |
| PMP22peripheral myelin protein 22 | Dažnai (30–79%) | 2 ligose |
| POLGDNA polymerase gamma, catalytic subunit | Dažnai (30–79%) | 2 ligose |
| PRNPprion protein (Kanno blood group) | Dažnai (30–79%) | 1 ligoje |
| PRRT2proline rich transmembrane protein 2 | Dažnai (30–79%) | 2 ligose |
| RRM1ribonucleotide reductase catalytic subunit M1 | Dažnai (30–79%) | 1 ligoje |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Dažnai (30–79%) | 1 ligoje |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Dažnai (30–79%) | 1 ligoje |
| SCYL1SCY1 like pseudokinase 1 | Dažnai (30–79%) | 2 ligose |
| SEPTIN9septin 9 | Dažnai (30–79%) | 1 ligoje |
| SLC2A1solute carrier family 2 member 1 | Dažnai (30–79%) | 3 ligose |
Rodyti dar 87 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| THPOthrombopoietin | Dažnai (30–79%) | 1 ligoje |
| TK2thymidine kinase 2 | Dažnai (30–79%) | 1 ligoje |
| TOP3ADNA topoisomerase III alpha | Dažnai (30–79%) | 1 ligoje |
| TRIM32tripartite motif containing 32 | Dažnai (30–79%) | 1 ligoje |
| TYMPthymidine phosphorylase | Dažnai (30–79%) | 1 ligoje |
| ATMATM serine/threonine kinase | Kartais (5–29%) | 1 ligoje |
| ATXN1ataxin 1 | Kartais (5–29%) | 1 ligoje |
| BMPR1Abone morphogenetic protein receptor type 1A | Kartais (5–29%) | 1 ligoje |
| BRCA2BRCA2 DNA repair associated | Kartais (5–29%) | 1 ligoje |
| C4Acomplement C4A (Chido/Rodgers blood group) | Kartais (5–29%) | 1 ligoje |
| CBLIFcobalamin binding intrinsic factor | Kartais (5–29%) | 2 ligose |
| CCND1cyclin D1 | Kartais (5–29%) | 1 ligoje |
| CCR1C-C motif chemokine receptor 1 | Kartais (5–29%) | 1 ligoje |
| CHEK2checkpoint kinase 2 | Kartais (5–29%) | 1 ligoje |
| COQ6coenzyme Q6, monooxygenase | Kartais (5–29%) | 1 ligoje |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Kartais (5–29%) | 1 ligoje |
| EPCAMepithelial cell adhesion molecule | Kartais (5–29%) | 1 ligoje |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Kartais (5–29%) | 1 ligoje |
| ERLIN2ER lipid raft associated 2 | Kartais (5–29%) | 1 ligoje |
| FASFas cell surface death receptor | Kartais (5–29%) | 1 ligoje |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Kartais (5–29%) | 1 ligoje |
| GNA14G protein subunit alpha 14 | Kartais (5–29%) | 1 ligoje |
| GNASGNAS complex locus | Kartais (5–29%) | 4 ligose |
| GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A | Kartais (5–29%) | 1 ligoje |
| HINT1histidine triad nucleotide binding protein 1 | Kartais (5–29%) | 1 ligoje |
| HLA-Bmajor histocompatibility complex, class I, B | Kartais (5–29%) | 2 ligose |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Kartais (5–29%) | 2 ligose |
| HPDL4-hydroxyphenylpyruvate dioxygenase like | Kartais (5–29%) | 1 ligoje |
| IFNGR1interferon gamma receptor 1 | Kartais (5–29%) | 1 ligoje |
| IL10interleukin 10 | Kartais (5–29%) | 1 ligoje |
| IL12Ainterleukin 12A | Kartais (5–29%) | 1 ligoje |
| IL12A-AS1IL12A antisense RNA 1 | Kartais (5–29%) | 1 ligoje |
| IL23Rinterleukin 23 receptor | Kartais (5–29%) | 1 ligoje |
| KIF5Akinesin family member 5A | Kartais (5–29%) | 1 ligoje |
| KLRC4killer cell lectin like receptor C4 | Kartais (5–29%) | 1 ligoje |
| KRASKRas proto-oncogene, GTPase | Kartais (5–29%) | 1 ligoje |
| LZTR1leucine zipper like post translational regulator 1 | Kartais (5–29%) | 1 ligoje |
| MEFVMEFV innate immunity regulator, pyrin | Kartais (5–29%) | 1 ligoje |
| MEN1menin 1 | Kartais (5–29%) | 1 ligoje |
| MLH1mutL homolog 1 | Kartais (5–29%) | 1 ligoje |
| MSH2mutS homolog 2 | Kartais (5–29%) | 1 ligoje |
| MSH6mutS homolog 6 | Kartais (5–29%) | 1 ligoje |
| MUTYHmutY DNA glycosylase | Kartais (5–29%) | 1 ligoje |
| NAGAalpha-N-acetylgalactosaminidase | Kartais (5–29%) | 1 ligoje |
| NEFLneurofilament light chain | Kartais (5–29%) | 1 ligoje |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Kartais (5–29%) | 1 ligoje |
| NPATnuclear protein, coactivator of histone transcription | Kartais (5–29%) | 1 ligoje |
| NPRL2NPR2 like, GATOR1 complex subunit | Kartais (5–29%) | 1 ligoje |
| NPRL3NPR3 like, GATOR1 complex subunit | Kartais (5–29%) | 1 ligoje |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Kartais (5–29%) | 1 ligoje |
| PMS1PMS1 homolog 1, mismatch repair system component | Kartais (5–29%) | 1 ligoje |
| PMS2PMS1 homolog 2, mismatch repair system component | Kartais (5–29%) | 1 ligoje |
| POLD1DNA polymerase delta 1, catalytic subunit | Kartais (5–29%) | 1 ligoje |
| POLEDNA polymerase epsilon, catalytic subunit | Kartais (5–29%) | 1 ligoje |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Kartais (5–29%) | 1 ligoje |
| RPS20ribosomal protein S20 | Kartais (5–29%) | 1 ligoje |
| SBF2SET binding factor 2 | Kartais (5–29%) | 1 ligoje |
| SCN3Asodium voltage-gated channel alpha subunit 3 | Kartais (5–29%) | 1 ligoje |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Kartais (5–29%) | 1 ligoje |
| SEMA4Asemaphorin 4A | Kartais (5–29%) | 1 ligoje |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Kartais (5–29%) | 1 ligoje |
| SRPX2sushi repeat containing protein X-linked 2 | Kartais (5–29%) | 1 ligoje |
| STAT4signal transducer and activator of transcription 4 | Kartais (5–29%) | 1 ligoje |
| STX16syntaxin 16 | Kartais (5–29%) | 1 ligoje |
| TGFBR2transforming growth factor beta receptor 2 | Kartais (5–29%) | 1 ligoje |
| TLR4toll like receptor 4 | Kartais (5–29%) | 1 ligoje |
| TNFRSF1ATNF receptor superfamily member 1A | Kartais (5–29%) | 1 ligoje |
| UBAC2UBA domain containing 2 | Kartais (5–29%) | 1 ligoje |
| VCPvalosin containing protein | Kartais (5–29%) | 1 ligoje |
| VWA1von Willebrand factor A domain containing 1 | Kartais (5–29%) | 1 ligoje |
| YY1YY1 transcription factor | Kartais (5–29%) | 1 ligoje |
| CLCNKBchloride voltage-gated channel Kb | Retai (1–4 %) | 1 ligoje |
| GATA1GATA binding protein 1 | Retai (1–4 %) | 1 ligoje |
| SLC12A3solute carrier family 12 member 3 | Retai (1–4 %) | 2 ligose |
| TRAPPC2trafficking protein particle complex subunit 2 | Retai (1–4 %) | 1 ligoje |
| URODuroporphyrinogen decarboxylase | Retai (1–4 %) | 1 ligoje |
| UROSuroporphyrinogen III synthase | Retai (1–4 %) | 1 ligoje |
| ALADaminolevulinate dehydratase | Neužfiksuota | 1 ligoje |
| ATL1atlastin GTPase 1 | Neužfiksuota | 1 ligoje |
| CUBNcubilin | Neužfiksuota | 1 ligoje |
| GLAgalactosidase alpha | Neužfiksuota | 1 ligoje |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Neužfiksuota | 1 ligoje |
| HMBShydroxymethylbilane synthase | Neužfiksuota | 1 ligoje |
| KCNJ1potassium inwardly rectifying channel subfamily J member 1 | Neužfiksuota | 1 ligoje |
| MTHFRmethylenetetrahydrofolate reductase | Neužfiksuota | 1 ligoje |
| NAGLUN-acetyl-alpha-glucosaminidase | Neužfiksuota | 1 ligoje |
| SLC12A1solute carrier family 12 member 1 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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