Požymis
Lazy eye
Klinikinis pavadinimas: Amblyopia
Reduced visual acuity that is uncorrectable by lenses in the absence of detectable anatomic defects in the eye or visual pathways.
Santrauka
- Taip pat vadinama
- Wandering eye, Wandering eyes
- Kūno sistema
- Abnormality of the eye
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
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Įsigyti savo Genome Test126 genų susiję su Lazy eye
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Lazy eye. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| AHDC1AT-hook DNA binding motif containing 1 | Visada | 1 ligoje |
| CFAP20cilia and flagella associated protein 20 | Visada | 1 ligoje |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Visada | 1 ligoje |
| ESAMendothelial cell adhesion molecule | Visada | 1 ligoje |
| FDXRferredoxin reductase | Visada | 1 ligoje |
| FEM1Bfem-1 homolog B | Visada | 1 ligoje |
| HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 | Visada | 1 ligoje |
| LIM2lens intrinsic membrane protein 2 | Visada | 1 ligoje |
| MICU1mitochondrial calcium uptake 1 | Visada | 1 ligoje |
| NR6A1nuclear receptor subfamily 6 group A member 1 | Visada | 1 ligoje |
| NRLneural retina leucine zipper | Visada | 1 ligoje |
| SCN8Asodium voltage-gated channel alpha subunit 8 | Visada | 1 ligoje |
| TMEM216transmembrane protein 216 | Visada | 1 ligoje |
| WARS2tryptophanyl tRNA synthetase 2, mitochondrial | Visada | 2 ligose |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Labai dažnai (80–99%) | 1 ligoje |
| PAX6paired box 6 | Labai dažnai (80–99%) | 1 ligoje |
| ARHGEF2Rho/Rac guanine nucleotide exchange factor 2 | Dažnai (30–79%) | 1 ligoje |
| CBScystathionine beta-synthase | Dažnai (30–79%) | 1 ligoje |
| CLCN6Cl-/H+ antiporter 6 | Dažnai (30–79%) | 1 ligoje |
| COL11A1collagen type XI alpha 1 chain | Dažnai (30–79%) | 1 ligoje |
| COL25A1collagen type XXV alpha 1 chain | Dažnai (30–79%) | 1 ligoje |
| DNMBPdynamin binding protein | Dažnai (30–79%) | 1 ligoje |
| DOT1LDOT1 like histone lysine methyltransferase | Dažnai (30–79%) | 1 ligoje |
| ELP4elongator acetyltransferase complex subunit 4 | Dažnai (30–79%) | 1 ligoje |
| FOXL2forkhead box L2 | Dažnai (30–79%) | 1 ligoje |
| H4C3H4 clustered histone 3 | Dažnai (30–79%) | 1 ligoje |
| KAT6Alysine acetyltransferase 6A | Dažnai (30–79%) | 1 ligoje |
| KIF21Akinesin family member 21A | Dažnai (30–79%) | 1 ligoje |
| LAMA1laminin subunit alpha 1 | Dažnai (30–79%) | 2 ligose |
| OGTO-linked N-acetylglucosamine (GlcNAc) transferase | Dažnai (30–79%) | 1 ligoje |
| PHOX2Apaired like homeobox 2A | Dažnai (30–79%) | 2 ligose |
| POLR3GLRNA polymerase III subunit GL | Dažnai (30–79%) | 1 ligoje |
| PRR12proline rich 12 | Dažnai (30–79%) | 1 ligoje |
| RIC1RIC1 partner of RAB6A GEF complex | Dažnai (30–79%) | 1 ligoje |
| SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1 | Dažnai (30–79%) | 1 ligoje |
| TFE3transcription factor binding to IGHM enhancer 3 | Dažnai (30–79%) | 1 ligoje |
| TUBA1Atubulin alpha 1a | Dažnai (30–79%) | 1 ligoje |
| TUBB2Btubulin beta 2B class IIb | Dažnai (30–79%) | 1 ligoje |
| TUBB3tubulin beta 3 class III | Dažnai (30–79%) | 2 ligose |
| XYLT2xylosyltransferase 2 | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 86 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| YME1L1YME1 like 1 ATPase | Dažnai (30–79%) | 1 ligoje |
| ADAMTSL4ADAMTS like 4 | Kartais (5–29%) | 1 ligoje |
| AFF4ALF transcription elongation factor 4 | Kartais (5–29%) | 1 ligoje |
| AP1G1adaptor related protein complex 1 subunit gamma 1 | Kartais (5–29%) | 1 ligoje |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Kartais (5–29%) | 2 ligose |
| ATOH7atonal bHLH transcription factor 7 | Kartais (5–29%) | 1 ligoje |
| ATXN7L3ataxin 7 like 3 | Kartais (5–29%) | 1 ligoje |
| C1QBPcomplement C1q binding protein | Kartais (5–29%) | 1 ligoje |
| CDC42BPBCDC42 binding protein kinase beta | Kartais (5–29%) | 1 ligoje |
| CHN1chimerin 1 | Kartais (5–29%) | 2 ligose |
| CLN3CLN3 lysosomal/endosomal transmembrane protein, battenin | Kartais (5–29%) | 1 ligoje |
| COL8A2collagen type VIII alpha 2 chain | Kartais (5–29%) | 1 ligoje |
| COX7Bcytochrome c oxidase subunit 7B | Kartais (5–29%) | 1 ligoje |
| CRYBB1crystallin beta B1 | Kartais (5–29%) | 1 ligoje |
| CYP1B1cytochrome P450 family 1 subfamily B member 1 | Kartais (5–29%) | 1 ligoje |
| DAGLAdiacylglycerol lipase alpha | Kartais (5–29%) | 1 ligoje |
| DPP6dipeptidyl peptidase like 6 | Kartais (5–29%) | 1 ligoje |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Kartais (5–29%) | 1 ligoje |
| ELNelastin | Kartais (5–29%) | 1 ligoje |
| EPRS1glutamyl-prolyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| FAM177A1family with sequence similarity 177 member A1 | Kartais (5–29%) | 1 ligoje |
| FBN1fibrillin 1 | Kartais (5–29%) | 1 ligoje |
| FGFR2fibroblast growth factor receptor 2 | Kartais (5–29%) | 3 ligose |
| FGFR3fibroblast growth factor receptor 3 | Kartais (5–29%) | 2 ligose |
| FLNAfilamin A | Kartais (5–29%) | 1 ligoje |
| FZD4frizzled class receptor 4 | Kartais (5–29%) | 2 ligose |
| GRHL2grainyhead like transcription factor 2 | Kartais (5–29%) | 1 ligoje |
| H1-4H1.4 linker histone, cluster member | Kartais (5–29%) | 1 ligoje |
| HCCSholocytochrome c synthase | Kartais (5–29%) | 1 ligoje |
| HDAC4histone deacetylase 4 | Kartais (5–29%) | 1 ligoje |
| HIVEP2HIVEP zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| KCNN2potassium calcium-activated channel subfamily N member 2 | Kartais (5–29%) | 1 ligoje |
| KIF11kinesin family member 11 | Kartais (5–29%) | 1 ligoje |
| KMT2Dlysine methyltransferase 2D | Kartais (5–29%) | 1 ligoje |
| LMBRD2LMBR1 domain containing 2 | Kartais (5–29%) | 1 ligoje |
| LRP5LDL receptor related protein 5 | Kartais (5–29%) | 1 ligoje |
| LTBP2latent transforming growth factor beta binding protein 2 | Kartais (5–29%) | 1 ligoje |
| MAFBMAF bZIP transcription factor B | Kartais (5–29%) | 1 ligoje |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Kartais (5–29%) | 1 ligoje |
| MED25mediator complex subunit 25 | Kartais (5–29%) | 1 ligoje |
| MLXIPLMLX interacting protein like | Kartais (5–29%) | 1 ligoje |
| MYOCmyocilin | Kartais (5–29%) | 1 ligoje |
| NDPnorrin cystine knot growth factor NDP | Kartais (5–29%) | 2 ligose |
| NDUFB11NADH:ubiquinone oxidoreductase subunit B11 | Kartais (5–29%) | 1 ligoje |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Kartais (5–29%) | 1 ligoje |
| NFIXnuclear factor I X | Kartais (5–29%) | 1 ligoje |
| NOGnoggin | Kartais (5–29%) | 1 ligoje |
| NR2F1nuclear receptor subfamily 2 group F member 1 | Kartais (5–29%) | 1 ligoje |
| OVOL2ovo like zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| PDZD8PDZ domain containing 8 | Kartais (5–29%) | 1 ligoje |
| PIGNphosphatidylinositol glycan anchor biosynthesis class N | Kartais (5–29%) | 2 ligose |
| PRSS56serine protease 56 | Kartais (5–29%) | 1 ligoje |
| PUF60poly(U) binding splicing factor 60 | Kartais (5–29%) | 1 ligoje |
| RORARAR related orphan receptor A | Kartais (5–29%) | 1 ligoje |
| RRAS2RAS related 2 | Kartais (5–29%) | 1 ligoje |
| SALL4spalt like transcription factor 4 | Kartais (5–29%) | 1 ligoje |
| SF3B2splicing factor 3b subunit 2 | Kartais (5–29%) | 1 ligoje |
| SMOsmoothened, frizzled class receptor | Kartais (5–29%) | 1 ligoje |
| SOBPsine oculis binding protein homolog | Kartais (5–29%) | 1 ligoje |
| TANGO2transport and golgi organization 2 homolog | Kartais (5–29%) | 1 ligoje |
| TASP1taspase 1 | Kartais (5–29%) | 1 ligoje |
| TEKTEK receptor tyrosine kinase | Kartais (5–29%) | 1 ligoje |
| TRIOtrio Rho guanine nucleotide exchange factor | Kartais (5–29%) | 1 ligoje |
| TWIST1twist family bHLH transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| UFC1ubiquitin-fold modifier conjugating enzyme 1 | Kartais (5–29%) | 1 ligoje |
| VSX1visual system homeobox 1 | Kartais (5–29%) | 1 ligoje |
| VWA8von Willebrand factor A domain containing 8 | Kartais (5–29%) | 1 ligoje |
| WACWW domain containing adaptor with coiled-coil | Kartais (5–29%) | 1 ligoje |
| WDR26WD repeat domain 26 | Kartais (5–29%) | 2 ligose |
| ZEB1zinc finger E-box binding homeobox 1 | Kartais (5–29%) | 1 ligoje |
| ZFXzinc finger protein X-linked | Kartais (5–29%) | 1 ligoje |
| ADNPactivity dependent neuroprotector homeobox | Retai (1–4 %) | 1 ligoje |
| AP4B1adaptor related protein complex 4 subunit beta 1 | Retai (1–4 %) | 1 ligoje |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Retai (1–4 %) | 1 ligoje |
| AP4S1adaptor related protein complex 4 subunit sigma 1 | Retai (1–4 %) | 1 ligoje |
| PTBP1polypyrimidine tract binding protein 1 | Retai (1–4 %) | 1 ligoje |
| B3GAT3beta-1,3-glucuronyltransferase 3 | Neužfiksuota | 1 ligoje |
| CHST3carbohydrate sulfotransferase 3 | Neužfiksuota | 1 ligoje |
| COL4A1collagen type IV alpha 1 chain | Neužfiksuota | 1 ligoje |
| CRYAAcrystallin alpha A | Neužfiksuota | 1 ligoje |
| CRYGCcrystallin gamma C | Neužfiksuota | 1 ligoje |
| GPR143G protein-coupled receptor 143 | Neužfiksuota | 1 ligoje |
| NPHP4nephrocystin 4 | Neužfiksuota | 1 ligoje |
| PITX2paired like homeodomain 2 | Neužfiksuota | 1 ligoje |
| TBX1T-box transcription factor 1 | Neužfiksuota | 1 ligoje |
| ZMIZ1zinc finger MIZ-type containing 1 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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