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Požymis
Degenerative joint disease
Klinikinis pavadinimas: Osteoarthritis
Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.
Santrauka
- Kūno sistema
- Abnormality of the musculoskeletal system
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Ši puslapis kaip duomenys
Norėdami perskaityti jį kaip JSON, pridėkite .json prie puslapio adreso arba nurodykite application/json.
library(jsonlite)
url <- "https://dantelabs.com/traits/osteoarthritis.json"
page <- fromJSON(url)
page$trait$nameDegenerative joint diseaseHP:0002758
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Vienu tyrimu sužinokite genus, susijusius su Degenerative joint disease, ir kitą jūsų genomo dalį.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test49 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Epiphyseal and Spondyloepiphyseal DysplasiasReads 6 of these genesCOL9A1COL2A1COMPCOL9A2COL9A3MATN3About this report →
- Familial Isolated Pituitary Adenoma (FIPA / X-LAG)Reads 2 of these genesAIPGPR101About this report →
- Otospondylomegaepiphyseal Dysplasia (OSMED)Reads 2 of these genesCOL2A1COL11A2About this report →
- Loeys-Dietz SyndromeReads 3 of these genesSMAD2SMAD3TGFB3About this report →
Show 45 more reports
- HaemophiliaReads 2 of these genesF8F9About this report →
- Familial Paget Disease of BoneReads 2 of these genesTNFRSF11BZNF687About this report →
- ACAN-Related Short StatureReads 1 of these genesACANAbout this report →
- AlkaptonuriaReads 1 of these genesHGDAbout this report →
- Caffey DiseaseReads 1 of these genesCOL1A1About this report →
- CLCN7-Related Hypopigmentation, Organomegaly and Delayed Myelination (HOD)Reads 1 of these genesCLCN7About this report →
- Desbuquois Dysplasia 1Reads 1 of these genesCANT1About this report →
- Familial Mediterranean FeverReads 1 of these genesMEFVAbout this report →
- FGFR3-Related Chondrodysplasias (Achondroplasia and Related Conditions)Reads 1 of these genesFGFR3About this report →
- Gaucher DiseaseReads 1 of these genesGBA1About this report →
- Progressive Pseudorheumatoid DysplasiaReads 1 of these genesCCN6About this report →
- Restrictive Dermopathy (ZMPSTE24)Reads 1 of these genesZMPSTE24About this report →
- Wilson DiseaseReads 1 of these genesATP7BAbout this report →
- VitreoretinopathyReads 5 of these genesCOL9A1COL2A1COL11A1COL9A2COL9A3About this report →
- Marfan Like SyndromesReads 3 of these genesSMAD2SMAD3TGFB3About this report →
- Ehlers-Danlos SyndromeReads 4 of these genesAEBP1COL1A1COL5A1COL5A2About this report →
- Fibrodysplasia Ossificans ProgressivaReads 1 of these genesGNASAbout this report →
- Inherited ArthropathiesReads 1 of these genesANKHAbout this report →
- LipodystrophyReads 2 of these genesLMNAZMPSTE24About this report →
- Disorder of Copper MetabolismReads 1 of these genesATP7BAbout this report →
- Achondrogenesis panelReads 1 of these genesCOL2A1About this report →
- Pseudohypoparathyroidism & GNAS-Inactivation DisordersReads 1 of these genesGNASAbout this report →
- Growth Hormone Insensitivity & IGF-1 Axis DisordersReads 1 of these genesGHRAbout this report →
- HemochromatosisReads 1 of these genesSLC40A1About this report →
- Hereditary Rickets (Hypophosphatemic and Vitamin D-Dependent)Reads 1 of these genesPHEXAbout this report →
- Progressive Cardiac Conduction Disease & Sick Sinus SyndromeReads 1 of these genesLMNAAbout this report →
- ThrombophiliaReads 1 of these genesF9About this report →
- OsteopetrosisReads 1 of these genesCLCN7About this report →
- Parkinson DiseaseReads 1 of these genesGBA1About this report →
- Cutis LaxaReads 1 of these genesEMILIN1About this report →
- Charcot-Marie-Tooth DiseaseReads 2 of these genesEMILIN1LMNAAbout this report →
- Hereditary Sensory and Autonomic Neuropathies (incl. Familial Dysautonomia)Reads 1 of these genesNGFAbout this report →
- Syndromic CraniosynostosisReads 1 of these genesFGFR3About this report →
- Hearing Loss and DeafnessReads 2 of these genesCOL11A1COL11A2About this report →
- Rare Hereditary Peripheral NeuropathiesReads 3 of these genesEMILIN1NGFLMNAAbout this report →
- Spinal Muscular AtrophyReads 1 of these genesEMILIN1About this report →
- Amyotrophic Lateral Sclerosis (ALS)Reads 1 of these genesPFN1About this report →
- Thyroid CancerReads 1 of these genesGNASAbout this report →
- Limb-Girdle Muscular DystrophyReads 1 of these genesLMNAAbout this report →
- Osteogenesis ImperfectaReads 1 of these genesCOL1A1About this report →
- Epilepsy (Full Panel)Reads 2 of these genesUFSP2SCARB2About this report →
- Dilated CardiomyopathyReads 1 of these genesLMNAAbout this report →
- Lysosomal Storage DiseaseReads 1 of these genesGBA1About this report →
- Inherited Neurodegenerative DisordersReads 2 of these genesPFN1EMILIN1About this report →
- Congenital Disorders of GlycosylationReads 1 of these genesSTT3AAbout this report →
Vienu tyrimu sužinokite genus, susijusius su Degenerative joint disease, ir kitą jūsų genomo dalį.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test47 genų susiję su Degenerative joint disease
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Degenerative joint disease. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| AEBP1AE binding protein 1 | Visada | 1 ligoje |
| ANKHANKH inorganic pyrophosphate transport regulator | Visada | 2 ligose |
| COL9A1collagen type IX alpha 1 chain | Visada | 2 ligose |
| PFN1profilin 1 | Visada | 1 ligoje |
| SMAD2SMAD family member 2 | Visada | 1 ligoje |
| ACANaggrecan | Labai dažnai (80–99%) | 2 ligose |
| AIPAHR interacting HSP90 co-chaperone | Labai dažnai (80–99%) | 1 ligoje |
| CLCN7Cl-/H+ antiporter 7 | Labai dažnai (80–99%) | 1 ligoje |
| COL2A1collagen type II alpha 1 chain | Labai dažnai (80–99%) | 4 ligose |
| GPR101G protein-coupled receptor 101 | Labai dažnai (80–99%) | 1 ligoje |
| HGDhomogentisate 1,2-dioxygenase | Labai dažnai (80–99%) | 1 ligoje |
| UFSP2UFM1 specific peptidase 2 | Labai dažnai (80–99%) | 2 ligose |
| COL11A1collagen type XI alpha 1 chain | Dažnai (30–79%) | 1 ligoje |
| COL11A2collagen type XI alpha 2 chain | Dažnai (30–79%) | 2 ligose |
| COMPcartilage oligomeric matrix protein | Dažnai (30–79%) | 3 ligose |
| EMILIN1elastin microfibril interfacer 1 | Dažnai (30–79%) | 1 ligoje |
| HPGD15-hydroxyprostaglandin dehydrogenase | Dažnai (30–79%) | 1 ligoje |
| NGFnerve growth factor | Dažnai (30–79%) | 1 ligoje |
| SMAD3SMAD family member 3 | Dažnai (30–79%) | 2 ligose |
| TNFRSF11BTNF receptor superfamily member 11b | Dažnai (30–79%) | 1 ligoje |
| COL1A1collagen type I alpha 1 chain | Kartais (5–29%) | 1 ligoje |
| COL5A1collagen type V alpha 1 chain | Kartais (5–29%) | 2 ligose |
| COL5A2collagen type V alpha 2 chain | Kartais (5–29%) | 1 ligoje |
| COL9A2collagen type IX alpha 2 chain | Kartais (5–29%) | 1 ligoje |
| COL9A3collagen type IX alpha 3 chain | Kartais (5–29%) | 2 ligose |
| FGFR3fibroblast growth factor receptor 3 | Kartais (5–29%) | 1 ligoje |
| GBA1glucosylceramidase beta 1 | Kartais (5–29%) | 1 ligoje |
| GHRgrowth hormone receptor | Kartais (5–29%) | 1 ligoje |
| GNASGNAS complex locus | Kartais (5–29%) | 1 ligoje |
| LMNAlamin A/C | Kartais (5–29%) | 1 ligoje |
| MEFVMEFV innate immunity regulator, pyrin | Kartais (5–29%) | 1 ligoje |
| SCARB2scavenger receptor class B member 2 | Kartais (5–29%) | 1 ligoje |
| SLC40A1solute carrier family 40 member 1 | Kartais (5–29%) | 1 ligoje |
| STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A | Kartais (5–29%) | 1 ligoje |
| ZMPSTE24zinc metallopeptidase STE24 | Kartais (5–29%) | 1 ligoje |
| TGFB3transforming growth factor beta 3 | Retai (1–4 %) | 1 ligoje |
| ASPNasporin | Neužfiksuota | 1 ligoje |
| ATP7BATPase copper transporting beta | Neužfiksuota | 1 ligoje |
| CANT1calcium activated nucleotidase 1 | Neužfiksuota | 1 ligoje |
| CCN6cellular communication network factor 6 | Neužfiksuota | 1 ligoje |
Rodyti dar 7 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| F8coagulation factor VIII | Neužfiksuota | 1 ligoje |
| F9coagulation factor IX | Neužfiksuota | 1 ligoje |
| MATN3matrilin 3 | Neužfiksuota | 1 ligoje |
| MMP13matrix metallopeptidase 13 | Neužfiksuota | 1 ligoje |
| PHEXphosphate regulating endopeptidase X-linked | Neužfiksuota | 1 ligoje |
| TRPS1transcriptional repressor GATA binding 1 | Neužfiksuota | 1 ligoje |
| ZNF687zinc finger protein 687 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Siauresni požymiai
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Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.19-9814e911.
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
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Read the genes behind these traits in your own DNA.
The Genome Test sequences nearly all of your DNA, not a preset panel, so every gene on these pages is in your data. Premium adds 810+ physician-ready reports.
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