Požymis
Bone pain
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone.
Santrauka
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Bone pain, and the rest of your genome, with one test.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test90 genų susiję su Bone pain
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Bone pain. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| CYP27B1cytochrome P450 family 27 subfamily B member 1 | Visada | 2 ligose |
| GNASGNAS complex locus | Visada | 4 ligose |
| IL1R1interleukin 1 receptor type 1 | Visada | 1 ligoje |
| LPIN2lipin 2 | Visada | 2 ligose |
| PSAPprosaposin | Visada | 1 ligoje |
| SLC34A1solute carrier family 34 member 1 | Visada | 3 ligose |
| ATP7BATPase copper transporting beta | Labai dažnai (80–99%) | 1 ligoje |
| CLCN7Cl-/H+ antiporter 7 | Labai dažnai (80–99%) | 2 ligose |
| CYP19A1cytochrome P450 family 19 subfamily A member 1 | Labai dažnai (80–99%) | 1 ligoje |
| CYP2R1cytochrome P450 family 2 subfamily R member 1 | Labai dažnai (80–99%) | 2 ligose |
| DKK1dickkopf Wnt signaling pathway inhibitor 1 | Labai dažnai (80–99%) | 1 ligoje |
| DMP1dentin matrix acidic phosphoprotein 1 | Labai dažnai (80–99%) | 1 ligoje |
| ELANEelastase, neutrophil expressed | Labai dažnai (80–99%) | 1 ligoje |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Labai dažnai (80–99%) | 1 ligoje |
| EXT1exostosin glycosyltransferase 1 | Labai dažnai (80–99%) | 1 ligoje |
| GBA1glucosylceramidase beta 1 | Labai dažnai (80–99%) | 3 ligose |
| HPGD15-hydroxyprostaglandin dehydrogenase | Labai dažnai (80–99%) | 2 ligose |
| MAP2K1mitogen-activated protein kinase kinase 1 | Labai dažnai (80–99%) | 1 ligoje |
| NRASNRAS proto-oncogene, GTPase | Labai dažnai (80–99%) | 1 ligoje |
| OSTM1osteoclastogenesis associated transmembrane protein 1 | Labai dažnai (80–99%) | 1 ligoje |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Labai dažnai (80–99%) | 1 ligoje |
| RAD21RAD21 cohesin complex component | Labai dažnai (80–99%) | 1 ligoje |
| SCARB2scavenger receptor class B member 2 | Labai dažnai (80–99%) | 1 ligoje |
| SLCO2A1solute carrier organic anion transporter family member 2A1 | Labai dažnai (80–99%) | 1 ligoje |
| SNX10sorting nexin 10 | Labai dažnai (80–99%) | 1 ligoje |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Labai dažnai (80–99%) | 1 ligoje |
| TEKTEK receptor tyrosine kinase | Labai dažnai (80–99%) | 1 ligoje |
| TGFB1transforming growth factor beta 1 | Labai dažnai (80–99%) | 1 ligoje |
| TNFSF11TNF superfamily member 11 | Labai dažnai (80–99%) | 1 ligoje |
| TREM2triggering receptor expressed on myeloid cells 2 | Labai dažnai (80–99%) | 1 ligoje |
| TRPS1transcriptional repressor GATA binding 1 | Labai dažnai (80–99%) | 1 ligoje |
| TYROBPtransmembrane immune signaling adaptor TYROBP | Labai dažnai (80–99%) | 1 ligoje |
| VCPvalosin containing protein | Labai dažnai (80–99%) | 1 ligoje |
| VDRvitamin D receptor | Labai dažnai (80–99%) | 2 ligose |
| WNT1Wnt family member 1 | Labai dažnai (80–99%) | 1 ligoje |
| WNT3AWnt family member 3A | Labai dažnai (80–99%) | 1 ligoje |
| ASXL1ASXL transcriptional regulator 1 | Dažnai (30–79%) | 2 ligose |
| CBLCbl proto-oncogene | Dažnai (30–79%) | 1 ligoje |
| CCND1cyclin D1 | Dažnai (30–79%) | 1 ligoje |
| EHHADHenoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 50 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| FGF23fibroblast growth factor 23 | Dažnai (30–79%) | 2 ligose |
| GATMglycine amidinotransferase | Dažnai (30–79%) | 1 ligoje |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Dažnai (30–79%) | 1 ligoje |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Dažnai (30–79%) | 2 ligose |
| IDH2isocitrate dehydrogenase (NADP(+)) 2 | Dažnai (30–79%) | 2 ligose |
| NDUFAF6NADH:ubiquinone oxidoreductase complex assembly factor 6 | Dažnai (30–79%) | 1 ligoje |
| NOTCH2notch receptor 2 | Dažnai (30–79%) | 1 ligoje |
| PFN1profilin 1 | Dažnai (30–79%) | 1 ligoje |
| PHEXphosphate regulating endopeptidase X-linked | Dažnai (30–79%) | 2 ligose |
| PTH1Rparathyroid hormone 1 receptor | Dažnai (30–79%) | 1 ligoje |
| RUNX1RUNX family transcription factor 1 | Dažnai (30–79%) | 1 ligoje |
| SLC34A3solute carrier family 34 member 3 | Dažnai (30–79%) | 2 ligose |
| SRSF2serine and arginine rich splicing factor 2 | Dažnai (30–79%) | 2 ligose |
| TET2tet methylcytosine dioxygenase 2 | Dažnai (30–79%) | 2 ligose |
| ALKALK receptor tyrosine kinase | Kartais (5–29%) | 1 ligoje |
| BCORBCL6 corepressor | Kartais (5–29%) | 1 ligoje |
| CDC73cell division cycle 73 | Kartais (5–29%) | 2 ligose |
| FIP1L1factor interacting with PAPOLA and CPSF1 | Kartais (5–29%) | 1 ligoje |
| FOXE1forkhead box E1 | Kartais (5–29%) | 1 ligoje |
| HABP2hyaluronan binding protein 2 | Kartais (5–29%) | 1 ligoje |
| HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | Kartais (5–29%) | 1 ligoje |
| IRF2BP2interferon regulatory factor 2 binding protein 2 | Kartais (5–29%) | 1 ligoje |
| KITKIT proto-oncogene, receptor tyrosine kinase | Kartais (5–29%) | 1 ligoje |
| LEMD3LEM domain containing 3 | Kartais (5–29%) | 1 ligoje |
| LIN28Blin-28 RNA binding posttranscriptional regulator B | Kartais (5–29%) | 1 ligoje |
| LMO1LIM domain only 1 | Kartais (5–29%) | 1 ligoje |
| MINPP1multiple inositol-polyphosphate phosphatase 1 | Kartais (5–29%) | 1 ligoje |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Kartais (5–29%) | 1 ligoje |
| NABP1nucleic acid binding protein 1 | Kartais (5–29%) | 1 ligoje |
| NPM1nucleophosmin 1 | Kartais (5–29%) | 1 ligoje |
| NUMA1nuclear mitotic apparatus protein 1 | Kartais (5–29%) | 1 ligoje |
| PHOX2Bpaired like homeobox 2B | Kartais (5–29%) | 1 ligoje |
| PMLPML nuclear body scaffold | Kartais (5–29%) | 1 ligoje |
| POLEDNA polymerase epsilon, catalytic subunit | Kartais (5–29%) | 1 ligoje |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Kartais (5–29%) | 1 ligoje |
| PSMB8proteasome 20S subunit beta 8 | Kartais (5–29%) | 1 ligoje |
| RARAretinoic acid receptor alpha | Kartais (5–29%) | 1 ligoje |
| SERPINF2serpin family F member 2 | Kartais (5–29%) | 1 ligoje |
| STAT3signal transducer and activator of transcription 3 | Kartais (5–29%) | 1 ligoje |
| STAT5Bsignal transducer and activator of transcription 5B | Kartais (5–29%) | 1 ligoje |
| TBL1XR1TBL1X/Y related 1 | Kartais (5–29%) | 1 ligoje |
| ZBTB16zinc finger and BTB domain containing 16 | Kartais (5–29%) | 1 ligoje |
| TNFRSF1ATNF receptor superfamily member 1A | Retai (1–4 %) | 1 ligoje |
| AGXTalanine--glyoxylate aminotransferase | Neužfiksuota | 1 ligoje |
| AP2S1adaptor related protein complex 2 subunit sigma 1 | Neužfiksuota | 1 ligoje |
| CLCN5Cl-/H+ antiporter 5 | Neužfiksuota | 2 ligose |
| KIF1Bkinesin family member 1B | Neužfiksuota | 1 ligoje |
| SQSTM1sequestosome 1 | Neužfiksuota | 1 ligoje |
| TNFRSF11ATNF receptor superfamily member 11a | Neužfiksuota | 2 ligose |
| ZNF687zinc finger protein 687 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites