Egenskap
Lack of feeling, emotion, interest
Klinisk navn: Apathy
Apathy is a quantitative reduction of interest, motivation and the initiation and persistence of goal-directed behavior, where often the accompanying emotions, thoughts, and social interactions are also diminished. The individual is typically non-reactive to provocations, positive or negative, and appears to not care. Distinguished from lethargy which involves lack of physical or mental energy.
Sammendrag
- Også kalt
- Lack of feeling, emotion, interest, motivation, initiation, State of indifference
- Kroppssystem
- Abnormality of the nervous system
ReferansegenomGRCh38hg38
Posisjoner på gen- og variantsidene følger dette valget i denne nettleseren.
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Få mitt Genome Test94 gener knyttet til Lack of feeling, emotion, interest
Endringer i disse genene forårsaker sjeldne tilstander der Lack of feeling, emotion, interest forekommer. De fleste med denne egenskapen har ingen av disse tilstandene, og et gen på denne listen sier ingenting om noens eget genom.
| Gen | Hvor ofte den forekommer | Tilstander |
|---|---|---|
| APOEapolipoprotein E | Alltid | I 1 tilstand |
| GFAPglial fibrillary acidic protein | Alltid | I 1 tilstand |
| LAMB1laminin subunit beta 1 | Alltid | I 1 tilstand |
| PLP1proteolipid protein 1 | Alltid | I 1 tilstand |
| PSEN2presenilin 2 | Alltid | I 1 tilstand |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Alltid | I 1 tilstand |
| SCO2synthesis of cytochrome C oxidase 2 | Alltid | I 1 tilstand |
| VPS13Avacuolar protein sorting 13 homolog A | Alltid | I 2 tilstander |
| DCTN1dynactin subunit 1 | Svært ofte (80–99 %) | I 2 tilstander |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Svært ofte (80–99 %) | I 1 tilstand |
| ACAT1acetyl-CoA acetyltransferase 1 | Ofte (30–79 %) | I 1 tilstand |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Ofte (30–79 %) | I 2 tilstander |
| CDONcell adhesion associated, oncogene regulated | Ofte (30–79 %) | I 4 tilstander |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Ofte (30–79 %) | I 1 tilstand |
| COQ2coenzyme Q2, polyprenyltransferase | Ofte (30–79 %) | I 2 tilstander |
| CRIPTOcripto, EGF-CFC family member | Ofte (30–79 %) | I 4 tilstander |
| DISP1dispatched RND transporter family member 1 | Ofte (30–79 %) | I 4 tilstander |
| DLL1delta like canonical Notch ligand 1 | Ofte (30–79 %) | I 4 tilstander |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Ofte (30–79 %) | I 1 tilstand |
| FGF8fibroblast growth factor 8 | Ofte (30–79 %) | I 4 tilstander |
| FGFR1fibroblast growth factor receptor 1 | Ofte (30–79 %) | I 2 tilstander |
| FOXH1forkhead box H1 | Ofte (30–79 %) | I 4 tilstander |
| FUSFUS RNA binding protein | Ofte (30–79 %) | I 1 tilstand |
| GAS1growth arrest specific 1 | Ofte (30–79 %) | I 4 tilstander |
| GDAP2ganglioside induced differentiation associated protein 2 | Ofte (30–79 %) | I 1 tilstand |
| GLI2GLI family zinc finger 2 | Ofte (30–79 %) | I 4 tilstander |
| HMGCL3-hydroxy-3-methylglutaryl-CoA lyase | Ofte (30–79 %) | I 2 tilstander |
| HTRA2HtrA serine peptidase 2 | Ofte (30–79 %) | I 1 tilstand |
| HTThuntingtin | Ofte (30–79 %) | I 1 tilstand |
| LRRK2leucine rich repeat kinase 2 | Ofte (30–79 %) | I 2 tilstander |
| MAPTmicrotubule associated protein tau | Ofte (30–79 %) | I 6 tilstander |
| MRPL39mitochondrial ribosomal protein L39 | Ofte (30–79 %) | I 1 tilstand |
| NODALnodal growth differentiation factor | Ofte (30–79 %) | I 4 tilstander |
| NOTCH3notch receptor 3 | Ofte (30–79 %) | I 1 tilstand |
| PARK7Parkinsonism associated deglycase | Ofte (30–79 %) | I 1 tilstand |
| PINK1PTEN induced kinase 1 | Ofte (30–79 %) | I 1 tilstand |
| PLCH1phospholipase C eta 1 | Ofte (30–79 %) | I 1 tilstand |
| PODXLpodocalyxin like | Ofte (30–79 %) | I 1 tilstand |
| PRKAR1Bprotein kinase cAMP-dependent type I regulatory subunit beta | Ofte (30–79 %) | I 1 tilstand |
| PRKNparkin RBR E3 ubiquitin protein ligase | Ofte (30–79 %) | I 1 tilstand |
Vis 54 gener til
| Gen | Hvor ofte den forekommer | Tilstander |
|---|---|---|
| PRNPprion protein (Kanno blood group) | Ofte (30–79 %) | I 2 tilstander |
| PTCH1patched 1 | Ofte (30–79 %) | I 4 tilstander |
| SHHsonic hedgehog signaling molecule | Ofte (30–79 %) | I 4 tilstander |
| SIX3SIX homeobox 3 | Ofte (30–79 %) | I 4 tilstander |
| SLC2A3solute carrier family 2 member 3 | Ofte (30–79 %) | I 1 tilstand |
| SMC1Astructural maintenance of chromosomes 1A | Ofte (30–79 %) | I 1 tilstand |
| SNCAsynuclein alpha | Ofte (30–79 %) | I 2 tilstander |
| SQSTM1sequestosome 1 | Ofte (30–79 %) | I 3 tilstander |
| STAG2STAG2 cohesin complex component | Ofte (30–79 %) | I 2 tilstander |
| STILSTIL centriolar assembly protein | Ofte (30–79 %) | I 4 tilstander |
| SYNJ1synaptojanin 1 | Ofte (30–79 %) | I 1 tilstand |
| TARDBPTAR DNA binding protein | Ofte (30–79 %) | I 2 tilstander |
| TBK1TANK binding kinase 1 | Ofte (30–79 %) | I 2 tilstander |
| TGIF1TGFB induced factor homeobox 1 | Ofte (30–79 %) | I 4 tilstander |
| TRANK1tetratricopeptide repeat and ankyrin repeat containing 1 | Ofte (30–79 %) | I 1 tilstand |
| TSFMTs translation elongation factor, mitochondrial | Ofte (30–79 %) | I 1 tilstand |
| UCHL1ubiquitin C-terminal hydrolase L1 | Ofte (30–79 %) | I 1 tilstand |
| VCPvalosin containing protein | Ofte (30–79 %) | I 2 tilstander |
| VPS13Cvacuolar protein sorting 13 homolog C | Ofte (30–79 %) | I 2 tilstander |
| ZIC2Zic family zinc finger 2 | Ofte (30–79 %) | I 4 tilstander |
| ALADaminolevulinate dehydratase | Noen ganger (5–29 %) | I 1 tilstand |
| ATP13A2ATPase cation transporting 13A2 | Noen ganger (5–29 %) | I 1 tilstand |
| ATXN10ataxin 10 | Noen ganger (5–29 %) | I 1 tilstand |
| CHD2chromodomain helicase DNA binding protein 2 | Noen ganger (5–29 %) | I 1 tilstand |
| CHMP2Bcharged multivesicular body protein 2B | Noen ganger (5–29 %) | I 2 tilstander |
| CPceruloplasmin | Noen ganger (5–29 %) | I 1 tilstand |
| CUX2cut like homeobox 2 | Noen ganger (5–29 %) | I 1 tilstand |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Noen ganger (5–29 %) | I 1 tilstand |
| DNM1dynamin 1 | Noen ganger (5–29 %) | I 1 tilstand |
| EHMT1euchromatic histone lysine methyltransferase 1 | Noen ganger (5–29 %) | I 2 tilstander |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Noen ganger (5–29 %) | I 1 tilstand |
| GABRB3gamma-aminobutyric acid type A receptor subunit beta3 | Noen ganger (5–29 %) | I 1 tilstand |
| GBA1glucosylceramidase beta 1 | Noen ganger (5–29 %) | I 2 tilstander |
| GIGYF2GRB10 interacting GYF protein 2 | Noen ganger (5–29 %) | I 1 tilstand |
| GRNgranulin precursor | Noen ganger (5–29 %) | I 2 tilstander |
| HTRA1HtrA serine peptidase 1 | Noen ganger (5–29 %) | I 1 tilstand |
| MAPK10mitogen-activated protein kinase 10 | Noen ganger (5–29 %) | I 1 tilstand |
| PSEN1presenilin 1 | Noen ganger (5–29 %) | I 3 tilstander |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Noen ganger (5–29 %) | I 1 tilstand |
| TMEM106Btransmembrane protein 106B | Noen ganger (5–29 %) | I 1 tilstand |
| TREM2triggering receptor expressed on myeloid cells 2 | Noen ganger (5–29 %) | I 1 tilstand |
| TREX1three prime repair exonuclease 1 | Noen ganger (5–29 %) | I 1 tilstand |
| VPS35VPS35 retromer complex component | Noen ganger (5–29 %) | I 1 tilstand |
| BMP6bone morphogenetic protein 6 | Sjelden (1–4%) | I 1 tilstand |
| HFEhomeostatic iron regulator | Sjelden (1–4%) | I 1 tilstand |
| PDGFBplatelet derived growth factor subunit B | Sjelden (1–4%) | I 1 tilstand |
| C9orf72C9orf72-SMCR8 complex subunit | Ikke registrert | I 1 tilstand |
| DNMT1DNA methyltransferase 1 | Ikke registrert | I 1 tilstand |
| GM2Aganglioside GM2 activator | Ikke registrert | I 1 tilstand |
| HEXAhexosaminidase subunit alpha | Ikke registrert | I 1 tilstand |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Ikke registrert | I 1 tilstand |
| JPH3junctophilin 3 | Ikke registrert | I 1 tilstand |
| SPASTspastin | Ikke registrert | I 1 tilstand |
| TMEM240transmembrane protein 240 | Ikke registrert | I 1 tilstand |
Hvor ofte dette forekommer hos personer med en av genets tilstander, oppgitt som den hyppigste forekomsten blant dem, slik Human Phenotype Ontology registrerer den. Disse sidene beskriver egenskaper og forskningen bak dem. De er ikke en diagnose, og om symptomer bør du spørre lege eller genetisk rådgiver.
Bredere egenskaper
Slik er informasjonen samlet
- Human Phenotype Ontology, versjon 2026-09-01: egenskapen, navnene på den, definisjonen og genene som er knyttet til den. Les mer på hpo.jax.org.
- Datautgave 2026.10.16-c6eea6bf.
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