Požymis
Gum enlargement
Klinikinis pavadinimas: Gingival overgrowth
Hyperplasia of the gingiva (that is, a thickening of the soft tissue overlying the alveolar ridge. The degree of thickening ranges from involvement of the interdental papillae alone to gingival overgrowth covering the entire tooth crown.
Santrauka
- Taip pat vadinama
- Gingival enlargement, Gingival hyperplasia, Gum hypertrophy, Hypertrophic gingivitis
- Kūno sistema
- Abnormality of head or neck
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
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Įsigyti savo Genome Test124 genų susiję su Gum enlargement
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Gum enlargement. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ANKHANKH inorganic pyrophosphate transport regulator | Visada | 1 ligoje |
| ARID2AT-rich interaction domain 2 | Visada | 1 ligoje |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Visada | 2 ligose |
| DVL3dishevelled segment polarity protein 3 | Visada | 2 ligose |
| FBXO28F-box protein 28 | Visada | 1 ligoje |
| FGFR2fibroblast growth factor receptor 2 | Visada | 3 ligose |
| GCSHglycine cleavage system protein H | Visada | 1 ligoje |
| GLB1galactosidase beta 1 | Visada | 3 ligose |
| GPC3glypican 3 | Visada | 1 ligoje |
| KCNK4potassium two pore domain channel subfamily K member 4 | Visada | 1 ligoje |
| LBRlamin B receptor | Visada | 1 ligoje |
| MAP1Bmicrotubule associated protein 1B | Visada | 1 ligoje |
| NXNnucleoredoxin | Visada | 2 ligose |
| RIN2Ras and Rab interactor 2 | Visada | 2 ligose |
| SATB2SATB homeobox 2 | Visada | 1 ligoje |
| TBC1D24TBC1 domain family member 24 | Visada | 2 ligose |
| TMCO1transmembrane and coiled-coil domains 1 | Visada | 1 ligoje |
| AGAaspartylglucosaminidase | Labai dažnai (80–99%) | 1 ligoje |
| ANTXR2ANTXR cell adhesion molecule 2 | Labai dažnai (80–99%) | 3 ligose |
| CD96CD96 molecule | Labai dažnai (80–99%) | 1 ligoje |
| DVL1dishevelled segment polarity protein 1 | Labai dažnai (80–99%) | 3 ligose |
| FAM20AFAM20A golgi associated secretory pathway pseudokinase | Labai dažnai (80–99%) | 2 ligose |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Labai dažnai (80–99%) | 3 ligose |
| HYMAIhydatidiform mole associated and imprinted | Labai dažnai (80–99%) | 1 ligoje |
| KCNH1potassium voltage-gated channel subfamily H member 1 | Labai dažnai (80–99%) | 2 ligose |
| MMP2matrix metallopeptidase 2 | Labai dažnai (80–99%) | 1 ligoje |
| PLAGL1PLAG1 like zinc finger 1 | Labai dažnai (80–99%) | 1 ligoje |
| RESTRE1 silencing transcription factor | Labai dažnai (80–99%) | 1 ligoje |
| SOS1SOS Ras/Rac guanine nucleotide exchange factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| VPS13Bvacuolar protein sorting 13 homolog B | Labai dažnai (80–99%) | 1 ligoje |
| ABCA5ATP binding cassette subfamily A member 5 | Dažnai (30–79%) | 1 ligoje |
| ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif 2 | Dažnai (30–79%) | 2 ligose |
| ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3 | Dažnai (30–79%) | 1 ligoje |
| ADAMTSL2ADAMTS like 2 | Dažnai (30–79%) | 1 ligoje |
| AIMP2aminoacyl tRNA synthetase complex interacting multifunctional protein 2 | Dažnai (30–79%) | 1 ligoje |
| BGNbiglycan | Dažnai (30–79%) | 1 ligoje |
| CCBE1collagen and calcium binding EGF domains 1 | Dažnai (30–79%) | 2 ligose |
| DHCR77-dehydrocholesterol reductase | Dažnai (30–79%) | 1 ligoje |
| DNM1dynamin 1 | Dažnai (30–79%) | 1 ligoje |
| EMC1ER membrane protein complex subunit 1 | Dažnai (30–79%) | 2 ligose |
Rodyti dar 84 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| FAM20CFAM20C golgi associated secretory pathway kinase | Dažnai (30–79%) | 2 ligose |
| FAT4FAT atypical cadherin 4 | Dažnai (30–79%) | 1 ligoje |
| FGF3fibroblast growth factor 3 | Dažnai (30–79%) | 1 ligoje |
| FZD2frizzled class receptor 2 | Dažnai (30–79%) | 1 ligoje |
| GUSBglucuronidase beta | Dažnai (30–79%) | 1 ligoje |
| HIVEP2HIVEP zinc finger 2 | Dažnai (30–79%) | 1 ligoje |
| KCNJ6potassium inwardly rectifying channel subfamily J member 6 | Dažnai (30–79%) | 2 ligose |
| KCNMA1potassium calcium-activated channel subfamily M alpha 1 | Dažnai (30–79%) | 1 ligoje |
| KCNN3potassium calcium-activated channel subfamily N member 3 | Dažnai (30–79%) | 1 ligoje |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Dažnai (30–79%) | 1 ligoje |
| NFIXnuclear factor I X | Dažnai (30–79%) | 3 ligose |
| OSTM1osteoclastogenesis associated transmembrane protein 1 | Dažnai (30–79%) | 1 ligoje |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Dažnai (30–79%) | 2 ligose |
| PIGSphosphatidylinositol glycan anchor biosynthesis class S | Dažnai (30–79%) | 1 ligoje |
| PLGplasminogen | Dažnai (30–79%) | 2 ligose |
| PRMT7protein arginine methyltransferase 7 | Dažnai (30–79%) | 1 ligoje |
| RALGAPA1Ral GTPase activating protein catalytic subunit alpha 1 | Dažnai (30–79%) | 1 ligoje |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Dažnai (30–79%) | 1 ligoje |
| ROR2ROR family WNT receptor 2 | Dažnai (30–79%) | 2 ligose |
| SC5Dsterol-C5-desaturase | Dažnai (30–79%) | 1 ligoje |
| SH3PXD2BSH3 and PX domains 2B | Dažnai (30–79%) | 2 ligose |
| TBC1D2BTBC1 domain family member 2B | Dažnai (30–79%) | 1 ligoje |
| TBCKTBC1 domain containing kinase | Dažnai (30–79%) | 1 ligoje |
| WNT5AWnt family member 5A | Dažnai (30–79%) | 2 ligose |
| ZNHIT3zinc finger HIT-type containing 3 | Dažnai (30–79%) | 1 ligoje |
| AFF3ALF transcription elongation factor 3 | Kartais (5–29%) | 1 ligoje |
| ASXL3ASXL transcriptional regulator 3 | Kartais (5–29%) | 1 ligoje |
| ATG7autophagy related 7 | Kartais (5–29%) | 1 ligoje |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Kartais (5–29%) | 1 ligoje |
| BCORBCL6 corepressor | Kartais (5–29%) | 1 ligoje |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Kartais (5–29%) | 1 ligoje |
| CLIP2CAP-Gly domain containing linker protein 2 | Kartais (5–29%) | 1 ligoje |
| DDR2discoidin domain receptor tyrosine kinase 2 | Kartais (5–29%) | 1 ligoje |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Kartais (5–29%) | 1 ligoje |
| EIF4Heukaryotic translation initiation factor 4H | Kartais (5–29%) | 1 ligoje |
| ELNelastin | Kartais (5–29%) | 1 ligoje |
| EXTL3exostosin like glycosyltransferase 3 | Kartais (5–29%) | 1 ligoje |
| FBXO22F-box protein 22 | Kartais (5–29%) | 1 ligoje |
| FIP1L1factor interacting with PAPOLA and CPSF1 | Kartais (5–29%) | 1 ligoje |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Kartais (5–29%) | 1 ligoje |
| GNAQG protein subunit alpha q | Kartais (5–29%) | 1 ligoje |
| GTF2Igeneral transcription factor IIi | Kartais (5–29%) | 1 ligoje |
| GTF2IRD1GTF2I repeat domain containing 1 | Kartais (5–29%) | 1 ligoje |
| GTF2IRD2GTF2I repeat domain containing 2 | Kartais (5–29%) | 1 ligoje |
| IER3IP1immediate early response 3 interacting protein 1 | Kartais (5–29%) | 1 ligoje |
| INSRinsulin receptor | Kartais (5–29%) | 2 ligose |
| IRF2BP2interferon regulatory factor 2 binding protein 2 | Kartais (5–29%) | 1 ligoje |
| LIMK1LIM domain kinase 1 | Kartais (5–29%) | 1 ligoje |
| LMNB1lamin B1 | Kartais (5–29%) | 1 ligoje |
| METTL27methyltransferase like 27 | Kartais (5–29%) | 1 ligoje |
| MYSM1Myb like, SWIRM and MPN domains 1 | Kartais (5–29%) | 1 ligoje |
| NABP1nucleic acid binding protein 1 | Kartais (5–29%) | 1 ligoje |
| NCF1neutrophil cytosolic factor 1 | Kartais (5–29%) | 1 ligoje |
| NEU1neuraminidase 1 | Kartais (5–29%) | 2 ligose |
| NKX6-2NK6 homeobox 2 | Kartais (5–29%) | 1 ligoje |
| NPM1nucleophosmin 1 | Kartais (5–29%) | 1 ligoje |
| NUMA1nuclear mitotic apparatus protein 1 | Kartais (5–29%) | 1 ligoje |
| PIGNphosphatidylinositol glycan anchor biosynthesis class N | Kartais (5–29%) | 1 ligoje |
| PMLPML nuclear body scaffold | Kartais (5–29%) | 1 ligoje |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Kartais (5–29%) | 1 ligoje |
| RARAretinoic acid receptor alpha | Kartais (5–29%) | 1 ligoje |
| RFC2replication factor C subunit 2 | Kartais (5–29%) | 1 ligoje |
| SLC29A3solute carrier family 29 member 3 | Kartais (5–29%) | 1 ligoje |
| SLC35C1solute carrier family 35 member C1 | Kartais (5–29%) | 1 ligoje |
| STAT3signal transducer and activator of transcription 3 | Kartais (5–29%) | 1 ligoje |
| STAT5Bsignal transducer and activator of transcription 5B | Kartais (5–29%) | 1 ligoje |
| STX1Asyntaxin 1A | Kartais (5–29%) | 1 ligoje |
| TBL1XR1TBL1X/Y related 1 | Kartais (5–29%) | 1 ligoje |
| TBL2transducin beta like 2 | Kartais (5–29%) | 1 ligoje |
| TMEM270transmembrane protein 270 | Kartais (5–29%) | 1 ligoje |
| TRIM8tripartite motif containing 8 | Kartais (5–29%) | 1 ligoje |
| TWIST2twist family bHLH transcription factor 2 | Kartais (5–29%) | 1 ligoje |
| USP9Xubiquitin specific peptidase 9 X-linked | Kartais (5–29%) | 1 ligoje |
| VPS37DVPS37D subunit of ESCRT-I | Kartais (5–29%) | 1 ligoje |
| WDR26WD repeat domain 26 | Kartais (5–29%) | 1 ligoje |
| ZBTB16zinc finger and BTB domain containing 16 | Kartais (5–29%) | 1 ligoje |
| ZEB2zinc finger E-box binding homeobox 2 | Kartais (5–29%) | 2 ligose |
| KIF7kinesin family member 7 | Retai (1–4 %) | 1 ligoje |
| ABCC9ATP binding cassette subfamily C member 9 | Neužfiksuota | 1 ligoje |
| CNTNAP1contactin associated protein 1 | Neužfiksuota | 1 ligoje |
| IDUAalpha-L-iduronidase | Neužfiksuota | 1 ligoje |
| MAN2B1mannosidase alpha class 2B member 1 | Neužfiksuota | 1 ligoje |
| MMP14matrix metallopeptidase 14 | Neužfiksuota | 1 ligoje |
| SLC17A5solute carrier family 17 member 5 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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