Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Trait
Sparse hair
Reduced density of hairs.
Summary
- Also called
- Thin, sparse hair, Decreased hair growth, Decreased hair growth on body, Hypotrichosis, Marked hypotrichosis, Sparse hair since birth
- Body system
- Abnormality of the integument
Sparse hairHP:0008070
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Read the genes linked to Sparse hair, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test229 genes linked to Sparse hair
Changes in these genes cause rare conditions in which Sparse hair is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ALDH6A1aldehyde dehydrogenase 6 family member A1 | Always | In 1 condition |
| ANTXR1ANTXR cell adhesion molecule 1 | Always | In 1 condition |
| AP1B1adaptor related protein complex 1 subunit beta 1 | Always | In 1 condition |
| APCDD1APC down-regulated 1 | Always | In 2 conditions |
| C18orf32chromosome 18 open reading frame 32 | Always | In 1 condition |
| CDH3cadherin 3 | Always | In 1 condition |
| CEP57centrosomal protein 57 | Always | In 1 condition |
| CILK1ciliogenesis associated kinase 1 | Always | In 1 condition |
| CST6cystatin E/M | Always | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Always | In 1 condition |
| DSC3desmocollin 3 | Always | In 1 condition |
| DSG4desmoglein 4 | Always | In 3 conditions |
| EDAectodysplasin A | Always | In 2 conditions |
| EDARectodysplasin A receptor | Always | In 3 conditions |
| EDARADDEDAR associated via death domain | Always | In 5 conditions |
| EEFSECeukaryotic elongation factor, selenocysteine-tRNA specific | Always | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Always | In 2 conditions |
| FEM1Bfem-1 homolog B | Always | In 1 condition |
| GATAD2BGATA zinc finger domain containing 2B | Always | In 1 condition |
| GJA1gap junction protein alpha 1 | Always | In 4 conditions |
| GTPBP1GTP binding protein 1 | Always | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Always | In 3 conditions |
| IRX5iroquois homeobox 5 | Always | In 1 condition |
| KMT2Blysine methyltransferase 2B | Always | In 1 condition |
| KRT71keratin 71 | Always | In 1 condition |
| LIFRLIF receptor subunit alpha | Always | In 1 condition |
| LIPHlipase H | Always | In 2 conditions |
| LSSlanosterol synthase | Always | In 3 conditions |
| MAP2K2mitogen-activated protein kinase kinase 2 | Always | In 3 conditions |
| MARS1methionyl-tRNA synthetase 1 | Always | In 1 condition |
| MED25mediator complex subunit 25 | Always | In 1 condition |
| PERPp53 apoptosis effector related to PMP22 | Always | In 2 conditions |
| PKP1plakophilin 1 | Always | In 2 conditions |
| PLCB4phospholipase C beta 4 | Always | In 1 condition |
| PNPLA6patatin like domain 6, lysophospholipase | Always | In 2 conditions |
| PPP1CBprotein phosphatase 1 catalytic subunit beta | Always | In 1 condition |
| PRMT7protein arginine methyltransferase 7 | Always | In 1 condition |
| PRPS1phosphoribosyl pyrophosphate synthetase 1 | Always | In 1 condition |
| PTDSS1phosphatidylserine synthase 1 | Always | In 1 condition |
| PYCR1pyrroline-5-carboxylate reductase 1 | Always | In 1 condition |
Show 189 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| RAG1recombination activating 1 | Always | In 1 condition |
| RAG2recombination activating 2 | Always | In 1 condition |
| RIN2Ras and Rab interactor 2 | Always | In 1 condition |
| RNF113Aring finger protein 113A | Always | In 1 condition |
| SEC23ASEC23 homolog A, COPII component | Always | In 2 conditions |
| SHOC2SHOC2 leucine rich repeat scaffold protein | Always | In 1 condition |
| SNRPEsmall nuclear ribonucleoprotein polypeptide E | Always | In 2 conditions |
| SREBF1sterol regulatory element binding transcription factor 1 | Always | In 2 conditions |
| ST14ST14 transmembrane serine protease matriptase | Always | In 2 conditions |
| SUPT7LSPT7 like, STAGA complex subunit gamma | Always | In 1 condition |
| TOMM7translocase of outer mitochondrial membrane 7 | Always | In 1 condition |
| TRPS1transcriptional repressor GATA binding 1 | Always | In 2 conditions |
| UBE3Bubiquitin protein ligase E3B | Always | In 1 condition |
| WNT10AWnt family member 10A | Always | In 2 conditions |
| ZMPSTE24zinc metallopeptidase STE24 | Always | In 2 conditions |
| ARHGAP31Rho GTPase activating protein 31 | Very often (80–99%) | In 1 condition |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Very often (80–99%) | In 3 conditions |
| ATP6V1AATPase H+ transporting V1 subunit A | Very often (80–99%) | In 1 condition |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Very often (80–99%) | In 1 condition |
| ATP7AATPase copper transporting alpha | Very often (80–99%) | In 2 conditions |
| BRF1BRF1 general transcription factor IIIB subunit | Very often (80–99%) | In 1 condition |
| CDH1cadherin 1 | Very often (80–99%) | In 1 condition |
| CHD6chromodomain helicase DNA binding protein 6 | Very often (80–99%) | In 1 condition |
| DLL4delta like canonical Notch ligand 4 | Very often (80–99%) | In 1 condition |
| DOCK6dedicator of cytokinesis 6 | Very often (80–99%) | In 1 condition |
| EDA2Rectodysplasin A2 receptor | Very often (80–99%) | In 1 condition |
| EOGTEGF domain specific O-linked N-acetylglucosamine transferase | Very often (80–99%) | In 1 condition |
| ESCO2establishment of sister chromatid cohesion N-acetyltransferase 2 | Very often (80–99%) | In 2 conditions |
| GTPBP2GTP binding protein 2 | Very often (80–99%) | In 1 condition |
| HPD4-hydroxyphenylpyruvate dioxygenase | Very often (80–99%) | In 2 conditions |
| IFT122intraflagellar transport 122 | Very often (80–99%) | In 2 conditions |
| IFT43intraflagellar transport 43 | Very often (80–99%) | In 2 conditions |
| IFT52intraflagellar transport 52 | Very often (80–99%) | In 1 condition |
| KCTD1potassium channel tetramerization domain containing 1 | Very often (80–99%) | In 2 conditions |
| KDF1keratinocyte differentiation factor 1 | Very often (80–99%) | In 1 condition |
| KRT81keratin 81 | Very often (80–99%) | In 1 condition |
| KRT83keratin 83 | Very often (80–99%) | In 1 condition |
| KRT86keratin 86 | Very often (80–99%) | In 2 conditions |
| LMNAlamin A/C | Very often (80–99%) | In 2 conditions |
| LRP6LDL receptor related protein 6 | Very often (80–99%) | In 1 condition |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Very often (80–99%) | In 2 conditions |
| NFKBIANFKB inhibitor alpha | Very often (80–99%) | In 2 conditions |
| NOTCH1notch receptor 1 | Very often (80–99%) | In 1 condition |
| PHF6PHD finger protein 6 | Very often (80–99%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Very often (80–99%) | In 2 conditions |
| RBPJrecombination signal binding protein for immunoglobulin kappa J region | Very often (80–99%) | In 1 condition |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Very often (80–99%) | In 2 conditions |
| RNU4ATACRNA, U4atac small nuclear | Very often (80–99%) | In 2 conditions |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Very often (80–99%) | In 2 conditions |
| SPINK5serine peptidase inhibitor Kazal type 5 | Very often (80–99%) | In 1 condition |
| TRAF6TNF receptor associated factor 6 | Very often (80–99%) | In 1 condition |
| TRPV3transient receptor potential cation channel subfamily V member 3 | Very often (80–99%) | In 2 conditions |
| TWIST2twist family bHLH transcription factor 2 | Very often (80–99%) | In 4 conditions |
| WDR19WD repeat domain 19 | Very often (80–99%) | In 1 condition |
| WDR35WD repeat domain 35 | Very often (80–99%) | In 3 conditions |
| AARS1alanyl-tRNA synthetase 1 | Often (30–79%) | In 1 condition |
| ABCA12ATP binding cassette subfamily A member 12 | Often (30–79%) | In 1 condition |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Often (30–79%) | In 1 condition |
| AHSGalpha 2-HS glycoprotein | Often (30–79%) | In 1 condition |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Often (30–79%) | In 1 condition |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Often (30–79%) | In 1 condition |
| ALX4ALX homeobox 4 | Often (30–79%) | In 1 condition |
| ANAPC1anaphase promoting complex subunit 1 | Often (30–79%) | In 2 conditions |
| ASPRV1aspartic peptidase retroviral like 1 | Often (30–79%) | In 1 condition |
| BCORL1BCL6 corepressor like 1 | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 2 conditions |
| CANT1calcium activated nucleotidase 1 | Often (30–79%) | In 1 condition |
| CAV1caveolin 1 | Often (30–79%) | In 1 condition |
| CBLCbl proto-oncogene | Often (30–79%) | In 1 condition |
| CLMPCXADR like cell adhesion molecule | Often (30–79%) | In 1 condition |
| COL11A1collagen type XI alpha 1 chain | Often (30–79%) | In 1 condition |
| CSGALNACT1chondroitin sulfate N-acetylgalactosaminyltransferase 1 | Often (30–79%) | In 1 condition |
| CTC1CST telomere replication complex component 1 | Often (30–79%) | In 2 conditions |
| CYP4F22cytochrome P450 family 4 subfamily F member 22 | Often (30–79%) | In 1 condition |
| DKC1dyskerin pseudouridine synthase 1 | Often (30–79%) | In 1 condition |
| DSG1desmoglein 1 | Often (30–79%) | In 1 condition |
| EXOSC2exosome component 2 | Often (30–79%) | In 1 condition |
| FLNAfilamin A | Often (30–79%) | In 1 condition |
| GJB2gap junction protein beta 2 | Often (30–79%) | In 1 condition |
| GJB6gap junction protein beta 6 | Often (30–79%) | In 2 conditions |
| IFT140intraflagellar transport 140 | Often (30–79%) | In 1 condition |
| ITGB6integrin subunit beta 6 | Often (30–79%) | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Often (30–79%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Often (30–79%) | In 4 conditions |
| LIPNlipase family member N | Often (30–79%) | In 1 condition |
| LPAR6lysophosphatidic acid receptor 6 | Often (30–79%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Often (30–79%) | In 2 conditions |
| MAPKAPK5MAPK activated protein kinase 5 | Often (30–79%) | In 1 condition |
| MTX2metaxin 2 | Often (30–79%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Often (30–79%) | In 1 condition |
| NFIXnuclear factor I X | Often (30–79%) | In 1 condition |
| NHP2NHP2 ribonucleoprotein | Often (30–79%) | In 1 condition |
| NIPAL4NIPA like domain containing 4 | Often (30–79%) | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Often (30–79%) | In 1 condition |
| NPM1nucleophosmin 1 | Often (30–79%) | In 1 condition |
| PARNpoly(A)-specific ribonuclease | Often (30–79%) | In 2 conditions |
| PI4KAphosphatidylinositol 4-kinase alpha | Often (30–79%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 1 condition |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 2 conditions |
| RECQL4RecQ like helicase 4 | Often (30–79%) | In 2 conditions |
| RPL21ribosomal protein L21 | Often (30–79%) | In 1 condition |
| RTEL1regulator of telomere elongation helicase 1 | Often (30–79%) | In 1 condition |
| SATB2SATB homeobox 2 | Often (30–79%) | In 3 conditions |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Often (30–79%) | In 1 condition |
| STING1stimulator of interferon response cGAMP interactor 1 | Often (30–79%) | In 1 condition |
| SULT2B1sulfotransferase family 2B member 1 | Often (30–79%) | In 1 condition |
| TERCtelomerase RNA component | Often (30–79%) | In 2 conditions |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 2 conditions |
| TGM1transglutaminase 1 | Often (30–79%) | In 3 conditions |
| TINF2TERF1 interacting nuclear factor 2 | Often (30–79%) | In 4 conditions |
| TSHZ3teashirt zinc finger homeobox 3 | Often (30–79%) | In 1 condition |
| TTC7Atetratricopeptide repeat domain 7A | Often (30–79%) | In 1 condition |
| TYMSthymidylate synthetase | Often (30–79%) | In 1 condition |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Often (30–79%) | In 1 condition |
| WNT10BWnt family member 10B | Often (30–79%) | In 1 condition |
| WRAP53WD repeat containing antisense to TP53 | Often (30–79%) | In 1 condition |
| XYLT1xylosyltransferase 1 | Often (30–79%) | In 1 condition |
| ASXL3ASXL transcriptional regulator 3 | Sometimes (5–29%) | In 1 condition |
| ATP2B1ATPase plasma membrane Ca2+ transporting 1 | Sometimes (5–29%) | In 1 condition |
| CACHD1cache domain containing 1 | Sometimes (5–29%) | In 1 condition |
| CACNA1Gcalcium voltage-gated channel subunit alpha1 G | Sometimes (5–29%) | In 1 condition |
| CAMK2Bcalcium/calmodulin dependent protein kinase II beta | Sometimes (5–29%) | In 1 condition |
| CDC42BPBCDC42 binding protein kinase beta | Sometimes (5–29%) | In 1 condition |
| CKAP2Lcytoskeleton associated protein 2L | Sometimes (5–29%) | In 1 condition |
| CREBBPCREB binding lysine acetyltransferase | Sometimes (5–29%) | In 1 condition |
| CWC27CWC27 spliceosome associated cyclophilin | Sometimes (5–29%) | In 1 condition |
| FOSL2FOS like 2, AP-1 transcription factor subunit | Sometimes (5–29%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Sometimes (5–29%) | In 1 condition |
| GSNgelsolin | Sometimes (5–29%) | In 1 condition |
| H3-3BH3.3 histone B | Sometimes (5–29%) | In 1 condition |
| KDM4Blysine demethylase 4B | Sometimes (5–29%) | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Sometimes (5–29%) | In 1 condition |
| LEF1lymphoid enhancer binding factor 1 | Sometimes (5–29%) | In 1 condition |
| MED16mediator complex subunit 16 | Sometimes (5–29%) | In 1 condition |
| MESDmesoderm development LRP chaperone | Sometimes (5–29%) | In 1 condition |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Sometimes (5–29%) | In 1 condition |
| NDUFA6NADH:ubiquinone oxidoreductase subunit A6 | Sometimes (5–29%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Sometimes (5–29%) | In 1 condition |
| NSRP1nuclear speckle splicing regulatory protein 1 | Sometimes (5–29%) | In 1 condition |
| NSUN2NOP2/Sun RNA methyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Sometimes (5–29%) | In 2 conditions |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Sometimes (5–29%) | In 1 condition |
| PDGFRBplatelet derived growth factor receptor beta | Sometimes (5–29%) | In 1 condition |
| POGZpogo transposable element derived with ZNF domain | Sometimes (5–29%) | In 1 condition |
| POP1POP1 ribonuclease P/MRP subunit | Sometimes (5–29%) | In 1 condition |
| PPP1R15Bprotein phosphatase 1 regulatory subunit 15B | Sometimes (5–29%) | In 2 conditions |
| PRIM1DNA primase subunit 1 | Sometimes (5–29%) | In 1 condition |
| SLC32A1solute carrier family 32 member 1 | Sometimes (5–29%) | In 1 condition |
| SPRED2sprouty related EVH1 domain containing 2 | Sometimes (5–29%) | In 1 condition |
| TAF1TATA-box binding protein associated factor 1 | Sometimes (5–29%) | In 1 condition |
| TFAP2Atranscription factor AP-2 alpha | Sometimes (5–29%) | In 1 condition |
| TMEM147transmembrane protein 147 | Sometimes (5–29%) | In 1 condition |
| TOGARAM1TOG array regulator of axonemal microtubules 1 | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 2 conditions |
| TRMT10AtRNA methyltransferase 10A | Sometimes (5–29%) | In 1 condition |
| ADAM17ADAM metallopeptidase domain 17 | Not recorded | In 1 condition |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Not recorded | In 1 condition |
| AXIN2axin 2 | Not recorded | In 1 condition |
| B3GALT6beta-1,3-galactosyltransferase 6 | Not recorded | In 1 condition |
| BRCA1BRCA1 DNA repair associated | Not recorded | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Not recorded | In 1 condition |
| CLDN1claudin 1 | Not recorded | In 1 condition |
| DCAF17DDB1 and CUL4 associated factor 17 | Not recorded | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Not recorded | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Not recorded | In 1 condition |
| EBPEBP cholestenol delta-isomerase | Not recorded | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Not recorded | In 1 condition |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Not recorded | In 1 condition |
| EXT2exostosin glycosyltransferase 2 | Not recorded | In 1 condition |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Not recorded | In 1 condition |
| FRMD4AFERM domain containing 4A | Not recorded | In 1 condition |
| HOXC13homeobox C13 | Not recorded | In 1 condition |
| HRHR lysine demethylase and nuclear receptor corepressor | Not recorded | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Not recorded | In 1 condition |
| HSPA9heat shock protein family A (Hsp70) member 9 | Not recorded | In 1 condition |
| KIFBPkinesin family binding protein | Not recorded | In 1 condition |
| KRT25keratin 25 | Not recorded | In 1 condition |
| MED12mediator complex subunit 12 | Not recorded | In 1 condition |
| MPLKIPM-phase specific PLK1 interacting protein | Not recorded | In 1 condition |
| POC1APOC1 centriolar protein A | Not recorded | In 1 condition |
| PQBP1polyglutamine binding protein 1 | Not recorded | In 1 condition |
| SKIC2SKI2 subunit of superkiller complex | Not recorded | In 1 condition |
| SKIC3SKI3 subunit of superkiller complex | Not recorded | In 1 condition |
| SLC7A7solute carrier family 7 member 7 | Not recorded | In 1 condition |
| SMAD4SMAD family member 4 | Not recorded | In 1 condition |
| THUMPD1THUMP domain 1 NAT10 acetyltransferase adaptor | Not recorded | In 1 condition |
| XRCC4X-ray repair cross complementing 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks