Skip to content
Use your HSA or FSA funds

Gene

POGZ

pogo transposable element derived with ZNF domain

Summary

Cytogenetic location
1q21.3
Coordinates
Chromosome 1: 151,402,724–151,459,494 (GRCh38)
Exons
19 exons across 56.8 kb
Protein
1,410 amino acids
Also known as
KIAA0461, ZNF635, ZNF280E
MANE Select transcript
ENST00000271715.7NM_015100.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Intellectual Disability

      • One of 233 genes linked to it

        • ClinGen rates the link definitive
        • 5 GenCC submitters rate it definitive or strong

    How POGZ is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    • Stretches short reads find hard
    Chromosome 1, with a bracket where POGZ sits. POGZ and 36 genes near it on chromosome 1, from 150,931,109 to 151,931,108.Chromosome 11q21.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44151 Mb151.2 Mb151.4 Mb151.6 Mb151.8 MbSETDB1: 150,926,263–150,964,748, forward strandSETDB1CERS2: 150,959,099–150,977,396, reverse strandCERS2ANXA9: 150,981,321–150,996,077, forward strandANXA9MINDY1: 150,995,125–151,008,376, reverse strandPRUNE1: 151,008,408–151,035,714, forward strandBNIPL: 151,036,321–151,047,720, forward strandC1orf56: 151,047,746–151,051,986, forward strandC1orf56CDC42SE1: 151,050,242–151,070,325, reverse strandCDC42SE1MLLT11: 151,054,177–151,069,544, forward strandMLLT11GABPB2: 151,070,514–151,130,109, forward strandGABPB2SEMA6C: 151,131,685–151,147,813, reverse strandTIPE2: 151,156,621–151,160,255, forward strandSCNM1: 151,156,664–151,179,006, forward strandSCNM1LYSMD1: 151,159,748–151,165,948, reverse strandTMOD4: 151,169,984–151,176,284, reverse strandTMOD4VPS72: 151,176,304–151,195,321, reverse strandVPS72PIP5K1A: 151,197,949–151,249,538, forward strandPIP5K1APSMD4: 151,254,709–151,279,502, forward strandPSMD4ZNF687: 151,281,502–151,292,180, forward strandZNF687PI4KB: 151,291,792–151,328,394, reverse strandPI4KBRFX5: 151,340,640–151,347,339, reverse strandRFX5SELENBP1: 151,364,157–151,372,716, reverse strandSELENBP1PSMB4: 151,399,556–151,401,941, forward strandPSMB4POGZ: 151,402,724–151,459,494, reverse strandPOGZCGN: 151,510,139–151,538,692, forward strandCGNTUFT1: 151,540,305–151,583,583, forward strandTUFT1SNX27: 151,611,985–151,699,091, forward strandSNX27CELF3: 151,700,058–151,716,803, reverse strandCELF3RIIAD1: 151,710,433–151,729,805, forward strandRIIAD1MRPL9: 151,759,643–151,763,522, reverse strandMRPL9OAZ3: 151,762,899–151,771,334, forward strandOAZ3TDRKH: 151,769,799–151,791,416, reverse strandTDRKHLINGO4: 151,800,264–151,805,419, reverse strandLINGO4RORC: 151,806,021–151,831,845, reverse strandRORCC2CD4D: 151,837,818–151,840,557, reverse strandC2CD4DTHEM5: 151,847,101–151,853,712, reverse strandTHEM5THEM4: 151,870,866–151,909,879, reverse strandTHEM4Diagram of POGZ: 19 exons on the reverse strand of chromosome 1Exon 19: 44 known disease-causing sitesExon 18: 1 known disease-causing siteExon 17: 4 known disease-causing sitesExon 16: 2 known disease-causing sitesExon 15: 5 known disease-causing sitesExon 14: 6 known disease-causing sitesExon 13: 5 known disease-causing sitesExon 12: 3 known disease-causing sitesExon 11: 1 known disease-causing siteExon 10: 5 known disease-causing sitesExon 9: 6 known disease-causing sitesExon 8: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 6: 4 known disease-causing sitesExon 5: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 4 known disease-causing sitesExon 19: 151,402,724–151,406,464, 3,741 basesExon 18: 151,406,607–151,406,631, 25 basesExon 17: 151,406,911–151,407,023, 113 basesExon 16: 151,407,235–151,407,291, 57 basesExon 15: 151,408,100–151,408,240, 141 basesExon 14: 151,408,409–151,408,581, 173 basesExon 13: 151,408,694–151,408,828, 135 basesExon 12: 151,411,625–151,411,771, 147 basesExon 11: 151,412,296–151,412,396, 101 basesExon 10: 151,423,397–151,423,551, 155 basesExon 9: 151,423,949–151,424,286, 338 basesExon 8: 151,424,955–151,425,061, 107 basesExon 7: 151,427,823–151,428,041, 219 basesExon 6: 151,428,123–151,428,413, 291 basesExon 5: 151,429,603–151,429,711, 109 basesExon 4: 151,430,666–151,430,841, 176 basesExon 3: 151,440,928–151,441,086, 159 basesExon 2: 151,442,081–151,442,205, 125 basesExon 1: 151,459,152–151,459,494, 343 bases191510515′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 6.7 kb of the gene's 56.8 kb; 4,233 of those bases code for the protein.

    How a genome test reads POGZ

    110

    positions in POGZ where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 56.8 kb of POGZ, introns included, not only the 6.7 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). POGZ gene: pogo transposable element derived with ZNF domain. Retrieved 17 October 2026, from https://dantelabs.com/genes/pogz

    Vancouver

    Dante Labs. POGZ gene: pogo transposable element derived with ZNF domain [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pogz

    One test. A lifetime of answers.

    From $449Free shipping · Results in 6–8 weeks

    Get my Genome Test