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Gene

NSRP1

nuclear speckle splicing regulatory protein 1

Summary

Cytogenetic location
17q11.2
Coordinates
Chromosome 17: 30,116,816–30,186,475 (GRCh38)
Exons
7 exons across 69.7 kb
Protein
558 amino acids
Also known as
DKFZP434K1421, NSrp70
Previous symbols
CCDC55
MANE Select transcript
ENST00000247026.10NM_032141.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads NSRP1 yet. The test sequences your whole genome, so your data includes it all the same.

How NSRP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where NSRP1 sits. NSRP1 and 7 genes near it on chromosome 17, from 29,651,646 to 30,651,645.Chromosome 1717q11.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.329.8 Mb30 Mb30.2 Mb30.4 Mb30.6 MbSSH2: 29,625,938–29,930,276, reverse strandSSH2EFCAB5: 29,929,200–30,108,452, forward strandEFCAB5NSRP1: 30,116,816–30,186,475, forward strandNSRP1SLC6A4: 30,194,258–30,238,482, reverse strandSLC6A4BLMH: 30,248,193–30,292,152, reverse strandBLMHTMIGD1: 30,310,988–30,334,098, reverse strandTMIGD1CPD: 30,378,545–30,469,989, forward strandCPDGOSR1: 30,477,362–30,528,309, forward strandGOSR1Diagram of NSRP1: 7 exons on the forward strand of chromosome 17Exon 7: 2 known disease-causing sitesExon 1: 30,116,816–30,116,863, 48 basesExon 2: 30,118,080–30,118,173, 94 basesExon 3: 30,172,542–30,172,598, 57 basesExon 4: 30,178,071–30,178,199, 129 basesExon 5: 30,179,090–30,179,297, 208 basesExon 6: 30,180,908–30,181,016, 109 basesExon 7: 30,184,615–30,186,475, 1,861 bases124675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 69.7 kb; 1,677 of those bases code for the protein.

How a genome test reads NSRP1

2

positions in NSRP1 where ClinVar classes a change as pathogenic or likely pathogenic

2 of them (100%) fall in regions short reads find hard.

  • Segmental duplications (2 sites)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 69.7 kb of NSRP1, introns included, not only the 2.5 kb of exons.

Traits linked to NSRP1

The Human Phenotype Ontology lists these as features of the rare conditions NSRP1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NSRP1 gene: nuclear speckle splicing regulatory protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/nsrp1

Vancouver

Dante Labs. NSRP1 gene: nuclear speckle splicing regulatory protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nsrp1

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