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Gene

CLMP

CXADR like cell adhesion molecule

Summary

Cytogenetic location
11q24.1
Coordinates
Chromosome 11: 123,069,872–123,195,248 (GRCh38)
Exons
7 exons across 125.4 kb
Protein
373 amino acids
Inheritance
Autosomal recessive
Also known as
ASAM, FLJ22415, ACAM
MANE Select transcript
ENST00000448775.4NM_024769.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated report relevant to this gene

  • Congenital Intestinal Atresia & Short Bowel

    • Congenital short bowel syndrome, autosomal recessiveAutosomal recessive

      A markedly shortened small intestine at birth, caused by CLMP variants, leading to poor absorption of nutrients.

      • 2 GenCC submitters rate it definitive or strong
      What knowing changes

      Early diagnosis supports nutritional planning, including parenteral nutrition where needed.

Inheritance

Autosomal recessive
It takes a changed copy from each parent. With one, you are a carrier and usually unaffected; when both parents are carriers, each child has a one-in-four chance of inheriting two.

How CLMP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where CLMP sits. CLMP and 7 genes near it on chromosome 11, from 122,632,560 to 123,632,559.Chromosome 1111q24.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25122.8 Mb123 Mb123.2 Mb123.4 Mb123.6 MbUBASH3B: 122,655,722–122,814,473, forward strandUBASH3BCRTAM: 122,829,482–122,872,643, forward strandCRTAMJHY: 122,882,683–122,963,865, forward strandJHYBSX: 122,977,570–122,981,834, reverse strandBSXHSPA8: 123,057,485–123,063,230, reverse strandHSPA8CLMP: 123,069,872–123,195,248, reverse strandCLMPGRAMD1B: 123,358,251–123,627,774, forward strandGRAMD1BSCN3B: 123,629,187–123,655,244, reverse strandSCN3BDiagram of CLMP: 7 exons on the reverse strand of chromosome 11Exon 5: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 1: 1 known disease-causing siteExon 7: 123,069,872–123,073,774, 3,903 basesExon 6: 123,074,702–123,074,843, 142 basesExon 5: 123,083,085–123,083,207, 123 basesExon 4: 123,083,680–123,083,847, 168 basesExon 3: 123,084,512–123,084,713, 202 basesExon 2: 123,097,795–123,097,952, 158 basesExon 1: 123,194,913–123,195,248, 336 bases764215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5 kb of the gene's 125.4 kb; 1,122 of those bases code for the protein.

How a genome test reads CLMP

5

positions in CLMP where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 125.4 kb of CLMP, introns included, not only the 5 kb of exons.

Traits linked to CLMP

The Human Phenotype Ontology lists these as features of the rare conditions CLMP can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CLMP gene: CXADR like cell adhesion molecule. Retrieved 17 October 2026, from https://dantelabs.com/genes/clmp

Vancouver

Dante Labs. CLMP gene: CXADR like cell adhesion molecule [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/clmp

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