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Gene

APCDD1

APC down-regulated 1

Summary

Cytogenetic location
18p11.22
Coordinates
Chromosome 18: 10,454,635–10,489,949 (GRCh38)
Exons
5 exons across 35.3 kb
Protein
514 amino acids
Also known as
B7323
MANE Select transcript
ENST00000355285.10NM_153000.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

How APCDD1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 18, with a bracket where APCDD1 sits. APCDD1 and 2 genes near it on chromosome 18, from 9,972,292 to 10,972,291.Chromosome 1818p11.22p11.32p11.31p11.23p11.22p11.21p11.1q11.1q11.2q12.1q12.2q12.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q2310 Mb10.2 Mb10.4 Mb10.6 Mb10.8 MbAPCDD1: 10,454,635–10,489,949, forward strandAPCDD1NAPG: 10,525,905–10,553,249, forward strandNAPGPIEZO2: 10,666,483–11,149,591, reverse strandPIEZO2Diagram of APCDD1: 5 exons on the forward strand of chromosome 18Exon 1: 10,454,635–10,455,039, 405 basesExon 2: 10,468,469–10,468,652, 184 basesExon 3: 10,471,530–10,472,061, 532 basesExon 4: 10,485,462–10,485,783, 322 basesExon 5: 10,487,590–10,489,949, 2,360 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.8 kb of the gene's 35.3 kb; 1,545 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). APCDD1 gene: APC down-regulated 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/apcdd1

Vancouver

Dante Labs. APCDD1 gene: APC down-regulated 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/apcdd1

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