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Gene

TRMT10A

tRNA methyltransferase 10A

Summary

Cytogenetic location
4q23
Coordinates
Chromosome 4: 99,546,711–99,564,039 (GRCh38)
Exons
8 exons across 17.3 kb
Protein
339 amino acids
Also known as
MGC27034, TRM10
Previous symbols
RG9MTD2
MANE Select transcript
ENST00000394876.7NM_001134665.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TRMT10A yet. The test sequences your whole genome, so your data includes it all the same.

How TRMT10A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 4, with a bracket where TRMT10A sits. TRMT10A and 15 genes near it on chromosome 4, from 99,055,375 to 100,055,374.Chromosome 44q23p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.299.2 Mb99.4 Mb99.6 Mb99.8 Mb100 MbMETAP1: 98,995,359–99,065,059, forward strandMETAP1ADH5: 99,070,978–99,088,822, reverse strandADH5ADH4: 99,123,502–99,157,792, reverse strandADH4ADH6: 99,202,424–99,219,537, reverse strandADH6ADH1A: 99,275,958–99,291,552, reverse strandADH1AADH1B: 99,304,971–99,321,659, reverse strandADH1BADH1C: 99,336,093–99,382,896, reverse strandADH1CADH7: 99,412,261–99,435,698, reverse strandADH7C4orf17: 99,511,012–99,542,303, forward strandC4orf17TRMT10A: 99,546,711–99,564,039, reverse strandTRMT10AMTTP: 99,564,081–99,623,997, forward strandMTTPC4orf54: 99,636,529–99,657,828, reverse strandC4orf54DAPP1: 99,816,729–99,872,335, forward strandDAPP1LAMTOR3: 99,874,948–99,894,428, reverse strandLAMTOR3DNAJB14: 99,896,248–99,946,726, reverse strandDNAJB14H2AZ1: 99,948,051–99,950,540, reverse strandH2AZ1Diagram of TRMT10A: 8 exons on the reverse strand of chromosome 4Exon 7: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 4: 2 known disease-causing sitesExon 3: 4 known disease-causing sitesExon 2: 4 known disease-causing sitesExon 8: 99,546,711–99,549,356, 2,646 basesExon 7: 99,550,885–99,550,990, 106 basesExon 6: 99,553,785–99,553,934, 150 basesExon 5: 99,556,146–99,556,220, 75 basesExon 4: 99,557,345–99,557,416, 72 basesExon 3: 99,558,049–99,558,211, 163 basesExon 2: 99,559,154–99,559,361, 208 basesExon 1: 99,563,913–99,564,039, 127 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 17.3 kb; 1,020 of those bases code for the protein.

How a genome test reads TRMT10A

14

positions in TRMT10A where ClinVar classes a change as pathogenic or likely pathogenic

2 of them (14%) fall in regions short reads find hard.

  • Low mappability (2 sites)Regions where 100 bp or 250 bp reads cannot be placed uniquely.

A whole genome covers all 17.3 kb of TRMT10A, introns included, not only the 3.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TRMT10A gene: tRNA methyltransferase 10A. Retrieved 16 October 2026, from https://dantelabs.com/genes/trmt10a

Vancouver

Dante Labs. TRMT10A gene: tRNA methyltransferase 10A [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/trmt10a

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