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Gene

SNRPE

small nuclear ribonucleoprotein polypeptide E

Summary

Cytogenetic location
1q32.1
Coordinates
Chromosome 1: 203,861,599–203,871,152 (GRCh38)
Exons
5 exons across 9.6 kb
Protein
92 amino acids
Also known as
Sm-E
MANE Select transcript
ENST00000414487.7NM_003094.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

How SNRPE is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where SNRPE sits. SNRPE and 13 genes near it on chromosome 1, from 203,366,376 to 204,366,375.Chromosome 11q32.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44203.4 Mb203.6 Mb203.8 Mb204 Mb204.2 MbPRELP: 203,475,760–203,491,352, forward strandPRELPOPTC: 203,494,118–203,509,238, forward strandOPTCATP2B4: 203,626,664–203,744,081, forward strandATP2B4LAX1: 203,765,169–203,778,175, forward strandLAX1ZC3H11A: 203,795,562–203,854,999, forward strandZC3H11AZBED6: 203,795,623–203,854,999, forward strandZBED6: 203,802,094–203,802,192, forward strandSNRPE: 203,861,599–203,871,152, forward strandSNRPESOX13: 204,073,106–204,127,744, forward strandSOX13ETNK2: 204,131,062–204,152,184, reverse strandETNK2REN: 204,154,815–204,190,324, reverse strandRENKISS1: 204,190,337–204,196,638, reverse strandKISS1GOLT1A: 204,198,157–204,214,121, reverse strandGOLT1APLEKHA6: 204,218,851–204,378,391, reverse strandPLEKHA6Diagram of SNRPE: 5 exons on the forward strand of chromosome 1Exon 1: 1 known disease-causing siteExon 1: 203,861,599–203,861,713, 115 basesExon 2: 203,862,196–203,862,222, 27 basesExon 3: 203,863,663–203,863,725, 63 basesExon 4: 203,865,041–203,865,119, 79 basesExon 5: 203,869,877–203,871,152, 1,276 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 9.6 kb; 279 of those bases code for the protein.

How a genome test reads SNRPE

1

position in SNRPE where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.6 kb of SNRPE, introns included, not only the 1.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SNRPE gene: small nuclear ribonucleoprotein polypeptide E. Retrieved 16 October 2026, from https://dantelabs.com/genes/snrpe

Vancouver

Dante Labs. SNRPE gene: small nuclear ribonucleoprotein polypeptide E [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/snrpe

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