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Gene

PAN2

poly(A) specific ribonuclease subunit PAN2

Summary

Cytogenetic location
12q13.3
Coordinates
Chromosome 12: 56,316,936–56,334,000 (GRCh38)
Exons
26 exons across 17.1 kb
Protein
1,198 amino acids
Also known as
KIAA0710, hPAN2
Previous symbols
USP52
MANE Select transcript
ENST00000440411.8NM_014871.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PAN2 yet. The test sequences your whole genome, so your data includes it all the same.

How PAN2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where PAN2 sits. PAN2 and 44 genes near it on chromosome 12, from 55,825,468 to 56,825,467.Chromosome 1212q13.3p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3356 Mb56.2 Mb56.4 Mb56.6 Mb56.8 Mb: 55,757,275–55,827,546, reverse strandDNAJC14: 55,818,839–55,830,824, reverse strandDNAJC14MMP19: 55,835,433–55,843,005, reverse strandMMP19PYM1: 55,901,413–55,932,618, reverse strandPYM1DGKA: 55,927,319–55,954,027, forward strandDGKAPMEL: 55,954,104–55,973,317, reverse strandPMELCDK2: 55,966,781–55,972,789, forward strandCDK2RAB5B: 55,973,859–55,996,683, forward strandRAB5BSUOX: 55,996,855–56,006,641, forward strandSUOXIKZF4: 56,007,392–56,038,435, forward strandIKZF4RPS26: 56,041,351–56,044,697, forward strandRPS26ERBB3: 56,076,799–56,103,505, forward strand: 56,101,331–56,109,289, forward strandPA2G4: 56,104,349–56,116,329, forward strandPA2G4RPL41: 56,116,585–56,117,967, forward strandZC3H10: 56,118,243–56,127,514, forward strandESYT1: 56,118,250–56,150,107, forward strandESYT1MYL6B: 56,151,966–56,159,647, forward strandMYL6BMYL6: 56,158,322–56,166,572, forward strandMYL6SMARCC2: 56,162,359–56,189,587, reverse strandSMARCC2RNF41: 56,202,179–56,224,275, reverse strandNABP2: 56,221,978–56,229,860, forward strandNABP2SLC39A5: 56,230,039–56,238,214, forward strandSLC39A5ANKRD52: 56,237,807–56,258,665, reverse strandANKRD52COQ10A: 56,266,846–56,271,736, forward strandCOQ10ACS: 56,271,699–56,300,395, reverse strandCS: 56,285,916–56,316,059, reverse strandCNPY2: 56,308,024–56,316,363, reverse strandCNPY2PAN2: 56,316,936–56,334,000, reverse strandPAN2IL23A: 56,334,174–56,340,410, forward strandIL23ASTAT2: 56,338,356–56,360,283, reverse strandSTAT2APOF: 56,360,565–56,362,862, reverse strandAPOFTIMELESS: 56,416,363–56,449,457, reverse strandTIMELESSMIP: 56,449,502–56,469,166, reverse strandMIP: 56,449,700–56,488,170, reverse strandSPRYD4: 56,468,537–56,479,708, forward strandSPRYD4GLS2: 56,470,945–56,488,414, reverse strandRBMS2: 56,521,807–56,617,037, forward strandRBMS2BAZ2A: 56,595,596–56,636,914, reverse strandBAZ2AATP5F1B: 56,637,490–56,646,079, reverse strandATP5F1BPTGES3: 56,651,663–56,688,408, reverse strandPTGES3NACA: 56,712,305–56,731,628, reverse strandNACA: 56,714,612–56,741,535, reverse strandPRIM1: 56,730,438–56,752,384, reverse strandPRIM1HSD17B6: 56,751,817–56,788,409, forward strandHSD17B6Diagram of PAN2: 26 exons on the reverse strand of chromosome 12Exon 24: 1 known disease-causing siteExon 26: 56,316,936–56,317,643, 708 basesExon 25: 56,318,237–56,318,434, 198 basesExon 24: 56,319,088–56,319,181, 94 basesExon 23: 56,319,308–56,319,487, 180 basesExon 22: 56,319,621–56,319,764, 144 basesExon 21: 56,319,864–56,320,021, 158 basesExon 20: 56,322,078–56,322,168, 91 basesExon 19: 56,322,423–56,322,482, 60 basesExon 18: 56,322,615–56,322,758, 144 basesExon 17: 56,323,062–56,323,209, 148 basesExon 16: 56,323,311–56,323,384, 74 basesExon 15: 56,323,500–56,323,598, 99 basesExon 14: 56,323,807–56,323,913, 107 basesExon 13: 56,324,049–56,324,185, 137 basesExon 12: 56,324,294–56,324,493, 200 basesExon 11: 56,324,581–56,324,709, 129 basesExon 10: 56,325,009–56,325,128, 120 basesExon 9: 56,325,335–56,325,454, 120 basesExon 8: 56,326,313–56,326,409, 97 basesExon 7: 56,326,617–56,326,959, 343 basesExon 6: 56,327,364–56,327,631, 268 basesExon 5: 56,327,995–56,328,072, 78 basesExon 4: 56,328,238–56,328,358, 121 basesExon 3: 56,328,472–56,328,641, 170 basesExon 2: 56,332,813–56,333,208, 396 basesExon 1: 56,333,862–56,334,000, 139 bases262422201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.5 kb of the gene's 17.1 kb; 3,597 of those bases code for the protein.

How a genome test reads PAN2

1

position in PAN2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 17.1 kb of PAN2, introns included, not only the 4.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PAN2 gene: poly(A) specific ribonuclease subunit PAN2. Retrieved 16 October 2026, from https://dantelabs.com/genes/pan2

Vancouver

Dante Labs. PAN2 gene: poly(A) specific ribonuclease subunit PAN2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/pan2

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