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Gene

CDC42BPB

CDC42 binding protein kinase beta

Summary

Cytogenetic location
14q32.32
Coordinates
Chromosome 14: 102,932,380–103,057,549 (GRCh38)
Exons
37 exons across 125.2 kb
Protein
1,711 amino acids
Also known as
MRCKB, KIAA1124
MANE Select transcript
ENST00000361246.7NM_006035.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CDC42BPB yet. The test sequences your whole genome, so your data includes it all the same.

How CDC42BPB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where CDC42BPB sits. CDC42BPB and 11 genes near it on chromosome 14, from 102,494,965 to 103,494,964.Chromosome 1414q32.32p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.33102.6 Mb102.8 Mb103 Mb103.2 Mb103.4 MbTECPR2: 102,362,933–102,502,477, forward strandTECPR2ANKRD9: 102,501,767–102,509,824, reverse strandANKRD9RCOR1: 102,592,649–102,743,672, forward strandRCOR1TRAF3: 102,777,326–102,911,500, forward strandTRAF3AMN: 102,922,639–102,933,596, forward strandAMNCDC42BPB: 102,932,380–103,057,549, reverse strandCDC42BPBLBHD2: 103,084,174–103,090,031, forward strandLBHD2EXOC3L4: 103,094,538–103,110,571, forward strandEXOC3L4TNFAIP2: 103,121,265–103,137,441, forward strandTNFAIP2EIF5: 103,333,544–103,345,025, forward strandEIF5: 103,334,237–103,335,932, forward strandMARK3: 103,385,361–103,503,835, forward strandMARK3Diagram of CDC42BPB: 37 exons on the reverse strand of chromosome 14Exon 33: 1 known disease-causing siteExon 32: 2 known disease-causing sitesExon 30: 1 known disease-causing siteExon 28: 2 known disease-causing sitesExon 25: 1 known disease-causing siteExon 24: 1 known disease-causing siteExon 20: 1 known disease-causing siteExon 19: 2 known disease-causing sitesExon 10: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 4: 2 known disease-causing sitesExon 1: 1 known disease-causing siteExon 37: 102,932,380–102,933,843, 1,464 basesExon 36: 102,938,104–102,938,174, 71 basesExon 35: 102,938,306–102,938,411, 106 basesExon 34: 102,939,610–102,939,727, 118 basesExon 33: 102,939,830–102,939,947, 118 basesExon 32: 102,940,046–102,940,130, 85 basesExon 31: 102,940,227–102,940,324, 98 basesExon 30: 102,943,891–102,944,487, 597 basesExon 29: 102,945,662–102,945,724, 63 basesExon 28: 102,946,468–102,946,684, 217 basesExon 27: 102,947,721–102,947,802, 82 basesExon 26: 102,949,765–102,949,904, 140 basesExon 25: 102,950,466–102,950,602, 137 basesExon 24: 102,952,498–102,952,603, 106 basesExon 23: 102,954,198–102,954,275, 78 basesExon 22: 102,954,602–102,954,688, 87 basesExon 21: 102,959,631–102,959,710, 80 basesExon 20: 102,963,061–102,963,155, 95 basesExon 19: 102,964,502–102,964,650, 149 basesExon 18: 102,966,282–102,966,387, 106 basesExon 17: 102,967,046–102,967,170, 125 basesExon 16: 102,968,253–102,968,358, 106 basesExon 15: 102,968,472–102,968,716, 245 basesExon 14: 102,970,151–102,970,261, 111 basesExon 13: 102,971,919–102,972,161, 243 basesExon 12: 102,974,016–102,974,149, 134 basesExon 11: 102,975,684–102,975,803, 120 basesExon 10: 102,975,883–102,976,049, 167 basesExon 9: 102,978,126–102,978,205, 80 basesExon 8: 102,980,773–102,981,021, 249 basesExon 7: 102,983,556–102,983,756, 201 basesExon 6: 102,986,487–102,986,580, 94 basesExon 5: 102,999,565–102,999,713, 149 basesExon 4: 103,003,928–103,004,023, 96 basesExon 3: 103,008,472–103,008,555, 84 basesExon 2: 103,012,097–103,012,188, 92 basesExon 1: 103,056,999–103,057,549, 551 bases37353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.8 kb of the gene's 125.2 kb; 5,136 of those bases code for the protein.

How a genome test reads CDC42BPB

23

positions in CDC42BPB where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 125.2 kb of CDC42BPB, introns included, not only the 6.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CDC42BPB gene: CDC42 binding protein kinase beta. Retrieved 17 October 2026, from https://dantelabs.com/genes/cdc42bpb

Vancouver

Dante Labs. CDC42BPB gene: CDC42 binding protein kinase beta [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cdc42bpb

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