Požymis
Autoimmunity
The occurrence of an immune reaction against the organism's own cells or tissues.
Santrauka
- Taip pat vadinama
- Autoimmune disease, Autoimmune disorder, Autoimmune condition
- Kūno sistema
- Abnormality of the immune system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Autoimmunity, and the rest of your genome, with one test.
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Įsigyti savo Genome Test128 genų susiję su Autoimmunity
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Autoimmunity. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| LCKLCK proto-oncogene, Src family tyrosine kinase | Visada | 1 ligoje |
| TBK1TANK binding kinase 1 | Visada | 1 ligoje |
| TRACT cell receptor alpha constant | Visada | 1 ligoje |
| AIREautoimmune regulator | Labai dažnai (80–99%) | 1 ligoje |
| CASP10caspase 10 | Labai dažnai (80–99%) | 1 ligoje |
| CAV1caveolin 1 | Labai dažnai (80–99%) | 2 ligose |
| CCN2cellular communication network factor 2 | Labai dažnai (80–99%) | 2 ligose |
| CCR6C-C motif chemokine receptor 6 | Labai dažnai (80–99%) | 2 ligose |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Labai dažnai (80–99%) | 1 ligoje |
| FASFas cell surface death receptor | Labai dažnai (80–99%) | 1 ligoje |
| FASLGFas ligand | Labai dažnai (80–99%) | 1 ligoje |
| FOXP3forkhead box P3 | Labai dažnai (80–99%) | 1 ligoje |
| GPR35G protein-coupled receptor 35 | Labai dažnai (80–99%) | 1 ligoje |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Labai dažnai (80–99%) | 1 ligoje |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Labai dažnai (80–99%) | 1 ligoje |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Labai dažnai (80–99%) | 1 ligoje |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Labai dažnai (80–99%) | 4 ligose |
| IL6interleukin 6 | Labai dažnai (80–99%) | 2 ligose |
| IRF5interferon regulatory factor 5 | Labai dažnai (80–99%) | 3 ligose |
| KIAA0319LKIAA0319 like | Labai dažnai (80–99%) | 1 ligoje |
| LACC1laccase domain multifunctional purine nucleosidase 1 | Labai dažnai (80–99%) | 1 ligoje |
| MIFmacrophage migration inhibitory factor | Labai dažnai (80–99%) | 1 ligoje |
| MST1macrophage stimulating 1 | Labai dažnai (80–99%) | 1 ligoje |
| PGM3phosphoglucomutase 3 | Labai dažnai (80–99%) | 1 ligoje |
| PRTN3proteinase 3 | Labai dažnai (80–99%) | 1 ligoje |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Labai dažnai (80–99%) | 2 ligose |
| SEMA4Dsemaphorin 4D | Labai dažnai (80–99%) | 1 ligoje |
| TCF4transcription factor 4 | Labai dažnai (80–99%) | 1 ligoje |
| ACP5acid phosphatase 5, tartrate resistant | Dažnai (30–79%) | 2 ligose |
| ADAadenosine deaminase | Dažnai (30–79%) | 2 ligose |
| ADARadenosine deaminase RNA specific | Dažnai (30–79%) | 1 ligoje |
| ANKRD55ankyrin repeat domain 55 | Dažnai (30–79%) | 1 ligoje |
| CD247CD247 molecule | Dažnai (30–79%) | 1 ligoje |
| DNASE1L3deoxyribonuclease 1L3 | Dažnai (30–79%) | 1 ligoje |
| FOXN1forkhead box N1 | Dažnai (30–79%) | 1 ligoje |
| IFIH1interferon induced with helicase C domain 1 | Dažnai (30–79%) | 1 ligoje |
| IGHG2immunoglobulin heavy constant gamma 2 (G2m marker) | Dažnai (30–79%) | 1 ligoje |
| IGKCimmunoglobulin kappa constant | Dažnai (30–79%) | 1 ligoje |
| IL12Ainterleukin 12A | Dažnai (30–79%) | 1 ligoje |
| IL12RB1interleukin 12 receptor subunit beta 1 | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 88 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| IL2RAinterleukin 2 receptor subunit alpha | Dažnai (30–79%) | 1 ligoje |
| IL2RBinterleukin 2 receptor subunit beta | Dažnai (30–79%) | 2 ligose |
| ITCHitchy E3 ubiquitin protein ligase | Dažnai (30–79%) | 2 ligose |
| LMNB2lamin B2 | Dažnai (30–79%) | 1 ligoje |
| LSM11LSM11, U7 small nuclear RNA associated | Dažnai (30–79%) | 1 ligoje |
| MMEL1membrane metalloendopeptidase like 1 | Dažnai (30–79%) | 1 ligoje |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Dažnai (30–79%) | 1 ligoje |
| PNPpurine nucleoside phosphorylase | Dažnai (30–79%) | 1 ligoje |
| POU2AF1POU class 2 homeobox associating factor 1 | Dažnai (30–79%) | 1 ligoje |
| PTPN2protein tyrosine phosphatase non-receptor type 2 | Dažnai (30–79%) | 1 ligoje |
| RNASEH2Aribonuclease H2 subunit A | Dažnai (30–79%) | 1 ligoje |
| RNASEH2Bribonuclease H2 subunit B | Dažnai (30–79%) | 1 ligoje |
| RNASEH2Cribonuclease H2 subunit C | Dažnai (30–79%) | 1 ligoje |
| RNU7-1RNA, U7 small nuclear 1 | Dažnai (30–79%) | 1 ligoje |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Dažnai (30–79%) | 1 ligoje |
| SPIBSpi-B transcription factor | Dažnai (30–79%) | 1 ligoje |
| STAT4signal transducer and activator of transcription 4 | Dažnai (30–79%) | 1 ligoje |
| TNFSF15TNF superfamily member 15 | Dažnai (30–79%) | 1 ligoje |
| TNPO3transportin 3 | Dažnai (30–79%) | 1 ligoje |
| TPP2tripeptidyl peptidase 2 | Dažnai (30–79%) | 1 ligoje |
| TREX1three prime repair exonuclease 1 | Dažnai (30–79%) | 1 ligoje |
| WASWASP actin nucleation promoting factor | Dažnai (30–79%) | 1 ligoje |
| ARVCFARVCF delta catenin family member | Kartais (5–29%) | 1 ligoje |
| BTKBruton tyrosine kinase | Kartais (5–29%) | 1 ligoje |
| CHD7chromodomain helicase DNA binding protein 7 | Kartais (5–29%) | 1 ligoje |
| CIITAclass II major histocompatibility complex transactivator | Kartais (5–29%) | 1 ligoje |
| COMTcatechol-O-methyltransferase | Kartais (5–29%) | 1 ligoje |
| DCLRE1CDNA cross-link repair 1C | Kartais (5–29%) | 2 ligose |
| DOCK8dedicator of cytokinesis 8 | Kartais (5–29%) | 1 ligoje |
| GP1BBglycoprotein Ib platelet subunit beta | Kartais (5–29%) | 1 ligoje |
| HIRAhistone cell cycle regulator | Kartais (5–29%) | 1 ligoje |
| HRHR lysine demethylase and nuclear receptor corepressor | Kartais (5–29%) | 1 ligoje |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Kartais (5–29%) | 1 ligoje |
| IL2RGinterleukin 2 receptor subunit gamma | Kartais (5–29%) | 1 ligoje |
| IL7Rinterleukin 7 receptor | Kartais (5–29%) | 1 ligoje |
| JMJD1Cjumonji domain containing 1C | Kartais (5–29%) | 1 ligoje |
| NFKBIANFKB inhibitor alpha | Kartais (5–29%) | 1 ligoje |
| NHEJ1non-homologous end joining factor 1 | Kartais (5–29%) | 1 ligoje |
| NUDCD3NudC domain containing 3 | Kartais (5–29%) | 1 ligoje |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Kartais (5–29%) | 2 ligose |
| PSMB10proteasome 20S subunit beta 10 | Kartais (5–29%) | 1 ligoje |
| RAG1recombination activating 1 | Kartais (5–29%) | 3 ligose |
| RAG2recombination activating 2 | Kartais (5–29%) | 2 ligose |
| RFX5regulatory factor X5 | Kartais (5–29%) | 1 ligoje |
| RFXANKregulatory factor X associated ankyrin containing protein | Kartais (5–29%) | 1 ligoje |
| RFXAPregulatory factor X associated protein | Kartais (5–29%) | 1 ligoje |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Kartais (5–29%) | 1 ligoje |
| RREB1ras responsive element binding protein 1 | Kartais (5–29%) | 1 ligoje |
| SEC24CSEC24 homolog C, COPII component | Kartais (5–29%) | 1 ligoje |
| TBX1T-box transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| TTC7Atetratricopeptide repeat domain 7A | Kartais (5–29%) | 2 ligose |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Kartais (5–29%) | 1 ligoje |
| CORINcorin, serine peptidase | Retai (1–4 %) | 1 ligoje |
| FLT1fms related receptor tyrosine kinase 1 | Retai (1–4 %) | 1 ligoje |
| HAVCR2hepatitis A virus cellular receptor 2 | Retai (1–4 %) | 1 ligoje |
| LEMD3LEM domain containing 3 | Retai (1–4 %) | 1 ligoje |
| MTHFD1methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 | Retai (1–4 %) | 1 ligoje |
| PI4KAphosphatidylinositol 4-kinase alpha | Retai (1–4 %) | 1 ligoje |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Retai (1–4 %) | 1 ligoje |
| STOX1storkhead box 1 | Retai (1–4 %) | 1 ligoje |
| ABCB11ATP binding cassette subfamily B member 11 | Neužfiksuota | 1 ligoje |
| ABCB4ATP binding cassette subfamily B member 4 | Neužfiksuota | 1 ligoje |
| AKT2AKT serine/threonine kinase 2 | Neužfiksuota | 1 ligoje |
| ATP8B1ATPase phospholipid transporting 8B1 | Neužfiksuota | 1 ligoje |
| C1GALT1C1C1GALT1 specific chaperone 1 | Neužfiksuota | 1 ligoje |
| C1QAcomplement C1q A chain | Neužfiksuota | 1 ligoje |
| C1Rcomplement C1r | Neužfiksuota | 1 ligoje |
| CD19CD19 molecule | Neužfiksuota | 1 ligoje |
| CR2complement C3d receptor 2 | Neužfiksuota | 1 ligoje |
| HNF1AHNF1 homeobox A | Neužfiksuota | 1 ligoje |
| ICOSinducible T cell costimulator | Neužfiksuota | 1 ligoje |
| ITKIL2 inducible T cell kinase | Neužfiksuota | 1 ligoje |
| MC2Rmelanocortin 2 receptor | Neužfiksuota | 1 ligoje |
| MRAPmelanocortin 2 receptor accessory protein | Neužfiksuota | 1 ligoje |
| NNTnicotinamide nucleotide transhydrogenase | Neužfiksuota | 1 ligoje |
| NR1H4nuclear receptor subfamily 1 group H member 4 | Neužfiksuota | 1 ligoje |
| NRASNRAS proto-oncogene, GTPase | Neužfiksuota | 1 ligoje |
| PAX4paired box 4 | Neužfiksuota | 1 ligoje |
| PRG4proteoglycan 4 | Neužfiksuota | 1 ligoje |
| PRKCDprotein kinase C delta | Neužfiksuota | 1 ligoje |
| SERPING1serpin family G member 1 | Neužfiksuota | 1 ligoje |
| STARsteroidogenic acute regulatory protein | Neužfiksuota | 1 ligoje |
| STAT3signal transducer and activator of transcription 3 | Neužfiksuota | 1 ligoje |
| TNFRSF13BTNF receptor superfamily member 13B | Neužfiksuota | 2 ligose |
| TNFRSF13CTNF receptor superfamily member 13C | Neužfiksuota | 1 ligoje |
| TRAPPC2trafficking protein particle complex subunit 2 | Neužfiksuota | 1 ligoje |
| TXNRD2thioredoxin reductase 2 | Neužfiksuota | 1 ligoje |
| ZAP70zeta chain of T cell receptor associated protein kinase 70 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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