Požymis
Chronic constipation
Constipation for longer than three months with fewer than 3 bowel movements per week, straining, lumpy or hard stools, and a sensation of anorectal obstruction or incomplete defecation.
Santrauka
- Taip pat vadinama
- Infrequent bowel movements
- Kūno sistema
- Abnormality of the digestive system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Chronic constipation, and the rest of your genome, with one test.
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Įsigyti savo Genome Test140 genų susiję su Chronic constipation
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Chronic constipation. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| AMOTL1angiomotin like 1 | Visada | 1 ligoje |
| ARID2AT-rich interaction domain 2 | Visada | 1 ligoje |
| ASH1LASH1 like histone lysine methyltransferase | Visada | 1 ligoje |
| B2Mbeta-2-microglobulin | Visada | 1 ligoje |
| BAIAP2BAR/IMD domain containing adaptor protein 2 | Visada | 1 ligoje |
| CCT3chaperonin containing TCP1 subunit 3 | Visada | 1 ligoje |
| CILK1ciliogenesis associated kinase 1 | Visada | 1 ligoje |
| CRNKL1crooked neck pre-mRNA splicing factor 1 | Visada | 1 ligoje |
| DCPSdecapping enzyme, scavenger | Visada | 1 ligoje |
| DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit | Visada | 1 ligoje |
| DOT1LDOT1 like histone lysine methyltransferase | Visada | 1 ligoje |
| ELF4E74 like ETS transcription factor 4 | Visada | 1 ligoje |
| ERBB2erb-b2 receptor tyrosine kinase 2 | Visada | 1 ligoje |
| FBXO28F-box protein 28 | Visada | 1 ligoje |
| FEM1Bfem-1 homolog B | Visada | 1 ligoje |
| GRIA1glutamate ionotropic receptor AMPA type subunit 1 | Visada | 1 ligoje |
| GTF3C3general transcription factor IIIC subunit 3 | Visada | 1 ligoje |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Visada | 1 ligoje |
| LBX1ladybird homeobox 1 | Visada | 1 ligoje |
| MYO1Hmyosin IH | Visada | 1 ligoje |
| NAA80N-alpha-acetyltransferase 80, NatH catalytic subunit | Visada | 1 ligoje |
| PACSIN3protein kinase C and casein kinase substrate in neurons 3 | Visada | 1 ligoje |
| PLCB4phospholipase C beta 4 | Visada | 1 ligoje |
| PPP2R5Cprotein phosphatase 2 regulatory subunit B'gamma | Visada | 1 ligoje |
| PRKG2protein kinase cGMP-dependent 2 | Visada | 1 ligoje |
| RNU6ATACRNA, U6atac small nuclear | Visada | 1 ligoje |
| RTN2reticulon 2 | Visada | 1 ligoje |
| SLC12A2solute carrier family 12 member 2 | Visada | 1 ligoje |
| SLC25A36solute carrier family 25 member 36 | Visada | 1 ligoje |
| SPARTspartin | Visada | 1 ligoje |
| SPINK5serine peptidase inhibitor Kazal type 5 | Visada | 1 ligoje |
| TM2D3TM2 domain containing 3 | Visada | 1 ligoje |
| TRIM8tripartite motif containing 8 | Visada | 1 ligoje |
| WASF1WASP family member 1 | Labai dažnai (80–99%) | 1 ligoje |
| ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase | Dažnai (30–79%) | 1 ligoje |
| ADNPactivity dependent neuroprotector homeobox | Dažnai (30–79%) | 1 ligoje |
| AFF3ALF transcription elongation factor 3 | Dažnai (30–79%) | 1 ligoje |
| BICRABRD4 interacting chromatin remodeling complex associated protein | Dažnai (30–79%) | 1 ligoje |
| CAMK2Bcalcium/calmodulin dependent protein kinase II beta | Dažnai (30–79%) | 1 ligoje |
| CAMTA1calmodulin binding transcription activator 1 | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 100 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| COL1A1collagen type I alpha 1 chain | Dažnai (30–79%) | 1 ligoje |
| COL5A1collagen type V alpha 1 chain | Dažnai (30–79%) | 1 ligoje |
| COL5A2collagen type V alpha 2 chain | Dažnai (30–79%) | 1 ligoje |
| CREBBPCREB binding lysine acetyltransferase | Dažnai (30–79%) | 1 ligoje |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Dažnai (30–79%) | 1 ligoje |
| EHMT1euchromatic histone lysine methyltransferase 1 | Dažnai (30–79%) | 1 ligoje |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Dažnai (30–79%) | 1 ligoje |
| EP300EP300 lysine acetyltransferase | Dažnai (30–79%) | 1 ligoje |
| FAR1fatty acyl-CoA reductase 1 | Dažnai (30–79%) | 1 ligoje |
| GBA1glucosylceramidase beta 1 | Dažnai (30–79%) | 1 ligoje |
| GIGYF2GRB10 interacting GYF protein 2 | Dažnai (30–79%) | 1 ligoje |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Dažnai (30–79%) | 1 ligoje |
| HIVEP2HIVEP zinc finger 2 | Dažnai (30–79%) | 1 ligoje |
| IGBP1immunoglobulin binding protein 1 | Dažnai (30–79%) | 1 ligoje |
| KLHL20kelch like family member 20 | Dažnai (30–79%) | 1 ligoje |
| LMNB2lamin B2 | Dažnai (30–79%) | 1 ligoje |
| LRRK2leucine rich repeat kinase 2 | Dažnai (30–79%) | 1 ligoje |
| MADDMAP kinase activating death domain | Dažnai (30–79%) | 2 ligose |
| MAGEL2MAGE family member L2 | Dažnai (30–79%) | 2 ligose |
| MARS2methionyl-tRNA synthetase 2, mitochondrial | Dažnai (30–79%) | 1 ligoje |
| MECP2methyl-CpG binding protein 2 | Dažnai (30–79%) | 1 ligoje |
| MED13mediator complex subunit 13 | Dažnai (30–79%) | 1 ligoje |
| MKRN3makorin ring finger protein 3 | Dažnai (30–79%) | 1 ligoje |
| MNX1motor neuron and pancreas homeobox 1 | Dažnai (30–79%) | 2 ligose |
| MSL3MSL complex subunit 3 | Dažnai (30–79%) | 1 ligoje |
| NGLY1N-glycanase 1 | Dažnai (30–79%) | 1 ligoje |
| NPAP1nuclear pore associated protein 1 | Dažnai (30–79%) | 1 ligoje |
| NSD2nuclear receptor binding SET domain protein 2 | Dažnai (30–79%) | 1 ligoje |
| OPA1OPA1 mitochondrial dynamin like GTPase | Dažnai (30–79%) | 1 ligoje |
| PAK2p21 (RAC1) activated kinase 2 | Dažnai (30–79%) | 1 ligoje |
| PPFIA3PPFI scaffold protein A3 | Dažnai (30–79%) | 1 ligoje |
| PPP1R21protein phosphatase 1 regulatory subunit 21 | Dažnai (30–79%) | 1 ligoje |
| PWAR1Prader Willi/Angelman region RNA 1 | Dažnai (30–79%) | 1 ligoje |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Dažnai (30–79%) | 1 ligoje |
| RAI1retinoic acid induced 1 | Dažnai (30–79%) | 1 ligoje |
| SETD1ASET domain containing 1A, histone lysine methyltransferase | Dažnai (30–79%) | 1 ligoje |
| SH2B1SH2B adaptor protein 1 | Dažnai (30–79%) | 1 ligoje |
| SLC38A3solute carrier family 38 member 3 | Dažnai (30–79%) | 1 ligoje |
| SMOsmoothened, frizzled class receptor | Dažnai (30–79%) | 1 ligoje |
| SNCAsynuclein alpha | Dažnai (30–79%) | 1 ligoje |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Dažnai (30–79%) | 1 ligoje |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Dažnai (30–79%) | 1 ligoje |
| SOX17SRY-box transcription factor 17 | Dažnai (30–79%) | 1 ligoje |
| SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit | Dažnai (30–79%) | 1 ligoje |
| TANC2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | Dažnai (30–79%) | 1 ligoje |
| TCEAL1transcription elongation factor A like 1 | Dažnai (30–79%) | 1 ligoje |
| TFE3transcription factor binding to IGHM enhancer 3 | Dažnai (30–79%) | 1 ligoje |
| TMCO1transmembrane and coiled-coil domains 1 | Dažnai (30–79%) | 1 ligoje |
| TRA2Btransformer 2 beta homolog | Dažnai (30–79%) | 1 ligoje |
| TRIOtrio Rho guanine nucleotide exchange factor | Dažnai (30–79%) | 3 ligose |
| UBE2Aubiquitin conjugating enzyme E2 A | Dažnai (30–79%) | 1 ligoje |
| UGP2UDP-glucose pyrophosphorylase 2 | Dažnai (30–79%) | 1 ligoje |
| USP7ubiquitin specific peptidase 7 | Dažnai (30–79%) | 1 ligoje |
| VPS35VPS35 retromer complex component | Dažnai (30–79%) | 1 ligoje |
| AFG2AAAA ATPase AFG2A | Kartais (5–29%) | 1 ligoje |
| ARSBarylsulfatase B | Kartais (5–29%) | 1 ligoje |
| CTCFCCCTC-binding factor | Kartais (5–29%) | 1 ligoje |
| EIF5Aeukaryotic translation initiation factor 5A | Kartais (5–29%) | 1 ligoje |
| GATAD2BGATA zinc finger domain containing 2B | Kartais (5–29%) | 1 ligoje |
| GNB2G protein subunit beta 2 | Kartais (5–29%) | 1 ligoje |
| H1-4H1.4 linker histone, cluster member | Kartais (5–29%) | 1 ligoje |
| H3-3AH3.3 histone A | Kartais (5–29%) | 1 ligoje |
| H3-3BH3.3 histone B | Kartais (5–29%) | 1 ligoje |
| H4C5H4 clustered histone 5 | Kartais (5–29%) | 1 ligoje |
| HNRNPH2heterogeneous nuclear ribonucleoprotein H2 | Kartais (5–29%) | 1 ligoje |
| HS2ST1heparan sulfate 2-O-sulfotransferase 1 | Kartais (5–29%) | 1 ligoje |
| IPO8importin 8 | Kartais (5–29%) | 1 ligoje |
| KMT5Blysine methyltransferase 5B | Kartais (5–29%) | 1 ligoje |
| LMNB1lamin B1 | Kartais (5–29%) | 1 ligoje |
| LRRC7leucine rich repeat containing 7 | Kartais (5–29%) | 1 ligoje |
| MOGSmannosyl-oligosaccharide glucosidase | Kartais (5–29%) | 1 ligoje |
| MYH11myosin heavy chain 11 | Kartais (5–29%) | 1 ligoje |
| ODC1ornithine decarboxylase 1 | Kartais (5–29%) | 1 ligoje |
| OTUD6BOTU deubiquitinase 6B | Kartais (5–29%) | 2 ligose |
| PHOX2Bpaired like homeobox 2B | Kartais (5–29%) | 1 ligoje |
| POGZpogo transposable element derived with ZNF domain | Kartais (5–29%) | 1 ligoje |
| POU4F1POU class 4 homeobox 1 | Kartais (5–29%) | 1 ligoje |
| PPP1CBprotein phosphatase 1 catalytic subunit beta | Kartais (5–29%) | 1 ligoje |
| PPP2R1Aprotein phosphatase 2 scaffold subunit Aalpha | Kartais (5–29%) | 1 ligoje |
| PSMB8proteasome 20S subunit beta 8 | Kartais (5–29%) | 1 ligoje |
| RORARAR related orphan receptor A | Kartais (5–29%) | 1 ligoje |
| SEC61A1SEC61 translocon subunit alpha 1 | Kartais (5–29%) | 1 ligoje |
| SGSM3small G protein signaling modulator 3 | Kartais (5–29%) | 1 ligoje |
| SLC32A1solute carrier family 32 member 1 | Kartais (5–29%) | 1 ligoje |
| SPOPspeckle type BTB/POZ protein | Kartais (5–29%) | 1 ligoje |
| TAOK1TAO kinase 1 | Kartais (5–29%) | 1 ligoje |
| TBCDtubulin folding cofactor D | Kartais (5–29%) | 1 ligoje |
| TNFRSF1ATNF receptor superfamily member 1A | Kartais (5–29%) | 1 ligoje |
| UFC1ubiquitin-fold modifier conjugating enzyme 1 | Kartais (5–29%) | 1 ligoje |
| UPF3BUPF3B regulator of nonsense mediated mRNA decay | Kartais (5–29%) | 1 ligoje |
| USP9Xubiquitin specific peptidase 9 X-linked | Kartais (5–29%) | 1 ligoje |
| ZNF292zinc finger protein 292 | Kartais (5–29%) | 1 ligoje |
| ADAT3adenosine deaminase tRNA specific 3 | Retai (1–4 %) | 1 ligoje |
| MARK2microtubule affinity regulating kinase 2 | Retai (1–4 %) | 1 ligoje |
| MEFVMEFV innate immunity regulator, pyrin | Retai (1–4 %) | 1 ligoje |
| ELNelastin | Neužfiksuota | 1 ligoje |
| FGF12fibroblast growth factor 12 | Neužfiksuota | 1 ligoje |
| MLXIPLMLX interacting protein like | Neužfiksuota | 1 ligoje |
| MLYCDmalonyl-CoA decarboxylase | Neužfiksuota | 1 ligoje |
| PCGF2polycomb group ring finger 2 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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