Požymis
Extra finger
Klinikinis pavadinimas: Hand polydactyly
A kind of polydactyly characterized by the presence of a supernumerary finger or fingers.
Santrauka
- Taip pat vadinama
- Finger polydactyly, Polydactyly of the hand, Supernumerary finger
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Extra finger, and the rest of your genome, with one test.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test86 genų susiję su Extra finger
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Extra finger. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| DYNC2LI1dynein cytoplasmic 2 light intermediate chain 1 | Labai dažnai (80–99%) | 1 ligoje |
| EVCEvC ciliary complex subunit 1 | Labai dažnai (80–99%) | 1 ligoje |
| EVC2EvC ciliary complex subunit 2 | Labai dažnai (80–99%) | 1 ligoje |
| GLI1GLI family zinc finger 1 | Labai dažnai (80–99%) | 1 ligoje |
| LMBR1limb development membrane protein 1 | Labai dažnai (80–99%) | 2 ligose |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Labai dažnai (80–99%) | 1 ligoje |
| PNPLA6patatin like domain 6, lysophospholipase | Labai dažnai (80–99%) | 1 ligoje |
| PRKACAprotein kinase cAMP-activated catalytic subunit alpha | Labai dažnai (80–99%) | 1 ligoje |
| PRKACBprotein kinase cAMP-activated catalytic subunit beta | Labai dažnai (80–99%) | 1 ligoje |
| PTENphosphatase and tensin homolog | Labai dažnai (80–99%) | 1 ligoje |
| SHHsonic hedgehog signaling molecule | Labai dažnai (80–99%) | 1 ligoje |
| EBPEBP cholestenol delta-isomerase | Dažnai (30–79%) | 1 ligoje |
| EFNB1ephrin B1 | Dažnai (30–79%) | 1 ligoje |
| OFD1OFD1 centriole and centriolar satellite protein | Dažnai (30–79%) | 3 ligose |
| ABCA12ATP binding cassette subfamily A member 12 | Kartais (5–29%) | 1 ligoje |
| ACOX1acyl-CoA oxidase 1 | Kartais (5–29%) | 1 ligoje |
| AHI1Abelson helper integration site 1 | Kartais (5–29%) | 2 ligose |
| ARL13BARF like GTPase 13B | Kartais (5–29%) | 1 ligoje |
| ARL3ARF like GTPase 3 | Kartais (5–29%) | 1 ligoje |
| ARMC9armadillo repeat containing 9 | Kartais (5–29%) | 1 ligoje |
| ARVCFARVCF delta catenin family member | Kartais (5–29%) | 1 ligoje |
| B9D1B9 domain containing 1 | Kartais (5–29%) | 1 ligoje |
| B9D2B9 domain containing 2 | Kartais (5–29%) | 1 ligoje |
| CBY1chibby 1, beta catenin antagonist | Kartais (5–29%) | 1 ligoje |
| CC2D2Acoiled-coil and C2 domain containing 2A | Kartais (5–29%) | 1 ligoje |
| CCDC22CCC complex scaffolding subunit CCDC22 | Kartais (5–29%) | 1 ligoje |
| CD96CD96 molecule | Kartais (5–29%) | 1 ligoje |
| CEP104centrosomal protein 104 | Kartais (5–29%) | 1 ligoje |
| CEP120centrosomal protein 120 | Kartais (5–29%) | 2 ligose |
| CEP290centrosomal protein 290 | Kartais (5–29%) | 1 ligoje |
| CEP41centrosomal protein 41 | Kartais (5–29%) | 2 ligose |
| COMTcatechol-O-methyltransferase | Kartais (5–29%) | 1 ligoje |
| CPLANE1ciliogenesis and planar polarity effector complex subunit 1 | Kartais (5–29%) | 2 ligose |
| CSPP1centrosome and spindle pole associated protein 1 | Kartais (5–29%) | 1 ligoje |
| DPYSL5dihydropyrimidinase like 5 | Kartais (5–29%) | 1 ligoje |
| FAM149B1family with sequence similarity 149 member B1 | Kartais (5–29%) | 1 ligoje |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Kartais (5–29%) | 1 ligoje |
| GJA1gap junction protein alpha 1 | Kartais (5–29%) | 1 ligoje |
| GP1BBglycoprotein Ib platelet subunit beta | Kartais (5–29%) | 1 ligoje |
| HESX1HESX homeobox 1 | Kartais (5–29%) | 1 ligoje |
Rodyti dar 46 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| HIRAhistone cell cycle regulator | Kartais (5–29%) | 1 ligoje |
| HYLS1HYLS1 centriolar and ciliogenesis associated | Kartais (5–29%) | 1 ligoje |
| IFT74intraflagellar transport 74 | Kartais (5–29%) | 1 ligoje |
| INPP5Einositol polyphosphate-5-phosphatase E | Kartais (5–29%) | 2 ligose |
| JMJD1Cjumonji domain containing 1C | Kartais (5–29%) | 1 ligoje |
| KATNIPkatanin interacting protein | Kartais (5–29%) | 1 ligoje |
| KIAA0586KIAA0586 | Kartais (5–29%) | 1 ligoje |
| KIAA0753KIAA0753 | Kartais (5–29%) | 2 ligose |
| KIF7kinesin family member 7 | Kartais (5–29%) | 1 ligoje |
| LHX3LIM homeobox 3 | Kartais (5–29%) | 1 ligoje |
| LHX4LIM homeobox 4 | Kartais (5–29%) | 1 ligoje |
| MKS1MKS transition zone complex subunit 1 | Kartais (5–29%) | 2 ligose |
| NEK1NIMA related kinase 1 | Kartais (5–29%) | 1 ligoje |
| NPHP1nephrocystin 1 | Kartais (5–29%) | 1 ligoje |
| PDE6Dphosphodiesterase 6D | Kartais (5–29%) | 2 ligose |
| PIBF1progesterone immunomodulatory binding factor 1 | Kartais (5–29%) | 1 ligoje |
| POU1F1POU class 1 homeobox 1 | Kartais (5–29%) | 1 ligoje |
| PROP1PROP paired-like homeobox 1 | Kartais (5–29%) | 1 ligoje |
| RAI1retinoic acid induced 1 | Kartais (5–29%) | 1 ligoje |
| RBM10RNA binding motif protein 10 | Kartais (5–29%) | 1 ligoje |
| RPGRIP1LRPGRIP1 like | Kartais (5–29%) | 1 ligoje |
| RREB1ras responsive element binding protein 1 | Kartais (5–29%) | 1 ligoje |
| SEC24CSEC24 homolog C, COPII component | Kartais (5–29%) | 1 ligoje |
| SUFUSUFU negative regulator of hedgehog signaling | Kartais (5–29%) | 1 ligoje |
| TBX1T-box transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| TCTN1tectonic family member 1 | Kartais (5–29%) | 1 ligoje |
| TCTN2tectonic family member 2 | Kartais (5–29%) | 1 ligoje |
| TCTN3tectonic family member 3 | Kartais (5–29%) | 3 ligose |
| TFAP2Btranscription factor AP-2 beta | Kartais (5–29%) | 1 ligoje |
| TMEM138transmembrane protein 138 | Kartais (5–29%) | 1 ligoje |
| TMEM216transmembrane protein 216 | Kartais (5–29%) | 2 ligose |
| TMEM218transmembrane protein 218 | Kartais (5–29%) | 1 ligoje |
| TMEM231transmembrane protein 231 | Kartais (5–29%) | 2 ligose |
| TMEM237transmembrane protein 237 | Kartais (5–29%) | 3 ligose |
| TMEM67transmembrane protein 67 | Kartais (5–29%) | 1 ligoje |
| TOGARAM1TOG array regulator of axonemal microtubules 1 | Kartais (5–29%) | 1 ligoje |
| TOPORSTOP1 binding arginine/serine rich protein, E3 ubiquitin ligase | Kartais (5–29%) | 1 ligoje |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Kartais (5–29%) | 1 ligoje |
| VPS35LVPS35 endosomal protein sorting factor like | Kartais (5–29%) | 1 ligoje |
| WASHC5WASH complex subunit 5 | Kartais (5–29%) | 1 ligoje |
| ZNF423zinc finger protein 423 | Kartais (5–29%) | 1 ligoje |
| SH2B1SH2B adaptor protein 1 | Retai (1–4 %) | 1 ligoje |
| BLMBLM RecQ like helicase | Neužfiksuota | 1 ligoje |
| CHD7chromodomain helicase DNA binding protein 7 | Neužfiksuota | 1 ligoje |
| TBC1D32TBC1 domain family member 32 | Neužfiksuota | 1 ligoje |
| ZIC3Zic family zinc finger 3 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Siauresni požymiai
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites