Tunnus
Overlapping toe
Describes a foot digit resting on the dorsal surface of an adjacent digit when the foot is at rest. Initially clawing may be dynamic and only noticeable on walking. Over time the plantar plate tears, subluxation occurs at the metatarsophalangeal joint (MTPJ), and the deformity becomes permanent.
Kokkuvõte
- Teised nimetused
- Crossover toe, Overlapping toes, Overriding toes
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Overlapping toe, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test91 geeni on seotud tunnusega Overlapping toe
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Overlapping toe. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| ALPK3alpha kinase 3 | Alati | Esineb 1 haiguses |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Alati | Esineb 1 haiguses |
| ATXN7L3ataxin 7 like 3 | Alati | Esineb 1 haiguses |
| CCDC22CCC complex scaffolding subunit CCDC22 | Alati | Esineb 1 haiguses |
| CCDC47coiled-coil domain containing 47 | Alati | Esineb 1 haiguses |
| EBPEBP cholestenol delta-isomerase | Alati | Esineb 2 haiguses |
| ERI1exoribonuclease 1 | Alati | Esineb 1 haiguses |
| FGFR2fibroblast growth factor receptor 2 | Alati | Esineb 1 haiguses |
| GNPNAT1glucosamine-phosphate N-acetyltransferase 1 | Alati | Esineb 1 haiguses |
| INTS8integrator complex subunit 8 | Alati | Esineb 1 haiguses |
| MED16mediator complex subunit 16 | Alati | Esineb 1 haiguses |
| MYH3myosin heavy chain 3 | Alati | Esineb 1 haiguses |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Alati | Esineb 1 haiguses |
| PTBP1polypyrimidine tract binding protein 1 | Alati | Esineb 1 haiguses |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Alati | Esineb 2 haiguses |
| RSPRY1ring finger and SPRY domain containing 1 | Alati | Esineb 2 haiguses |
| SOD1superoxide dismutase 1 | Alati | Esineb 1 haiguses |
| TBCKTBC1 domain containing kinase | Alati | Esineb 1 haiguses |
| TOP2BDNA topoisomerase II beta | Alati | Esineb 1 haiguses |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Alati | Esineb 1 haiguses |
| ZNF407zinc finger protein 407 | Alati | Esineb 1 haiguses |
| ATN1atrophin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| CHST11carbohydrate sulfotransferase 11 | Sageli (30–79%) | Esineb 1 haiguses |
| CPLX1complexin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| CTU2cytosolic thiouridylase subunit 2 | Sageli (30–79%) | Esineb 1 haiguses |
| DDX6DEAD-box helicase 6 | Sageli (30–79%) | Esineb 1 haiguses |
| EP300EP300 lysine acetyltransferase | Sageli (30–79%) | Esineb 1 haiguses |
| EXT2exostosin glycosyltransferase 2 | Sageli (30–79%) | Esineb 2 haiguses |
| HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | Sageli (30–79%) | Esineb 1 haiguses |
| IFT140intraflagellar transport 140 | Sageli (30–79%) | Esineb 1 haiguses |
| INTS1integrator complex subunit 1 | Sageli (30–79%) | Esineb 1 haiguses |
| MYOD1myogenic differentiation 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NEK9NIMA related kinase 9 | Sageli (30–79%) | Esineb 1 haiguses |
| OTUD6BOTU deubiquitinase 6B | Sageli (30–79%) | Esineb 2 haiguses |
| WSB2WD repeat and SOCS box containing 2 | Sageli (30–79%) | Esineb 1 haiguses |
| XYLT2xylosyltransferase 2 | Sageli (30–79%) | Esineb 1 haiguses |
| ACTBactin beta | Mõnikord (5–29%) | Esineb 1 haiguses |
| BORCS8BLOC-1 related complex subunit 8 | Mõnikord (5–29%) | Esineb 1 haiguses |
| BPTFbromodomain PHD finger transcription factor | Mõnikord (5–29%) | Esineb 1 haiguses |
| CDC42cell division cycle 42 | Mõnikord (5–29%) | Esineb 2 haiguses |
Näita veel 51 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| CREBBPCREB binding lysine acetyltransferase | Mõnikord (5–29%) | Esineb 1 haiguses |
| DLK1delta like non-canonical Notch ligand 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DOT1LDOT1 like histone lysine methyltransferase | Mõnikord (5–29%) | Esineb 1 haiguses |
| FEM1Bfem-1 homolog B | Mõnikord (5–29%) | Esineb 1 haiguses |
| GLI3GLI family zinc finger 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GTF3C3general transcription factor IIIC subunit 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| KAT8lysine acetyltransferase 8 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAPK1mitogen-activated protein kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MED12mediator complex subunit 12 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MED25mediator complex subunit 25 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MEG3maternally expressed 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| PDZD8PDZ domain containing 8 | Mõnikord (5–29%) | Esineb 1 haiguses |
| PPP1R21protein phosphatase 1 regulatory subunit 21 | Mõnikord (5–29%) | Esineb 1 haiguses |
| PUF60poly(U) binding splicing factor 60 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RAB11BRAB11B, member RAS oncogene family | Mõnikord (5–29%) | Esineb 1 haiguses |
| RNU5B-1RNA, U5B small nuclear 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RTL1retrotransposon Gag like 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SETBP1SET binding protein 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SIN3ASIN3 transcription regulator family member A | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLC35C1solute carrier family 35 member C1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLC6A1solute carrier family 6 member 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLC6A11solute carrier family 6 member 11 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Mõnikord (5–29%) | Esineb 1 haiguses |
| SOX5SRY-box transcription factor 5 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TCF4transcription factor 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TELO2telomere maintenance 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| THOC6THO complex subunit 6 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TMCO1transmembrane and coiled-coil domains 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TMEM260transmembrane protein 260 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TMEM94transmembrane protein 94 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TRAF7TNF receptor associated factor 7 | Mõnikord (5–29%) | Esineb 1 haiguses |
| UBE2Aubiquitin conjugating enzyme E2 A | Mõnikord (5–29%) | Esineb 1 haiguses |
| USP9Xubiquitin specific peptidase 9 X-linked | Mõnikord (5–29%) | Esineb 1 haiguses |
| ZFXzinc finger protein X-linked | Mõnikord (5–29%) | Esineb 1 haiguses |
| GJA5gap junction protein alpha 5 | Harva (1–4%) | Esineb 1 haiguses |
| GJA8gap junction protein alpha 8 | Harva (1–4%) | Esineb 1 haiguses |
| ARXaristaless related homeobox | Pole registreeritud | Esineb 1 haiguses |
| ASXL1ASXL transcriptional regulator 1 | Pole registreeritud | Esineb 1 haiguses |
| BLTP1bridge-like lipid transfer protein family member 1 | Pole registreeritud | Esineb 1 haiguses |
| DHCR77-dehydrocholesterol reductase | Pole registreeritud | Esineb 1 haiguses |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Pole registreeritud | Esineb 1 haiguses |
| GDF6growth differentiation factor 6 | Pole registreeritud | Esineb 1 haiguses |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Pole registreeritud | Esineb 1 haiguses |
| PCGF2polycomb group ring finger 2 | Pole registreeritud | Esineb 1 haiguses |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Pole registreeritud | Esineb 1 haiguses |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Pole registreeritud | Esineb 1 haiguses |
| SF3B4splicing factor 3b subunit 4 | Pole registreeritud | Esineb 1 haiguses |
| SLC6A9solute carrier family 6 member 9 | Pole registreeritud | Esineb 1 haiguses |
| SMAD4SMAD family member 4 | Pole registreeritud | Esineb 1 haiguses |
| TPM2tropomyosin 2 | Pole registreeritud | Esineb 1 haiguses |
| WIPI2WD repeat domain, phosphoinositide interacting 2 | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast