Požymis
Obstructive sleep apnea
Obstructive Sleep Apnea is a condition characterized by the obstruction of the airway and pauses in breathing during sleep, which occur multiple times throughout the night. It is related to the relaxation of muscle tone that typically happens during sleep, leading to a partial collapse of the soft tissues in the airway and causing airflow obstruction.
Santrauka
- Kūno sistema
- Abnormality of the nervous system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Obstructive sleep apnea, and the rest of your genome, with one test.
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Įsigyti savo Genome Test92 genų susiję su Obstructive sleep apnea
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Obstructive sleep apnea. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ALPK3alpha kinase 3 | Visada | 1 ligoje |
| AMOTL1angiomotin like 1 | Visada | 1 ligoje |
| ATXN7L3ataxin 7 like 3 | Visada | 1 ligoje |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Visada | 1 ligoje |
| DMDdystrophin | Visada | 1 ligoje |
| DOT1LDOT1 like histone lysine methyltransferase | Visada | 1 ligoje |
| FBXO28F-box protein 28 | Visada | 1 ligoje |
| FLNAfilamin A | Visada | 1 ligoje |
| FLVCR1FLVCR choline and heme transporter 1 | Visada | 1 ligoje |
| FXR1FMR1 autosomal homolog 1 | Visada | 2 ligose |
| MED16mediator complex subunit 16 | Visada | 1 ligoje |
| MSL2MSL complex subunit 2 | Visada | 1 ligoje |
| RFC4replication factor C subunit 4 | Visada | 1 ligoje |
| RNU2-2RNA, U2 small nuclear 2 | Visada | 1 ligoje |
| SOX17SRY-box transcription factor 17 | Visada | 1 ligoje |
| WSB2WD repeat and SOCS box containing 2 | Visada | 1 ligoje |
| AHDC1AT-hook DNA binding motif containing 1 | Labai dažnai (80–99%) | 2 ligose |
| ADRA2Aadrenoceptor alpha 2A | Dažnai (30–79%) | 1 ligoje |
| ASXL1ASXL transcriptional regulator 1 | Dažnai (30–79%) | 1 ligoje |
| ATN1atrophin 1 | Dažnai (30–79%) | 1 ligoje |
| BMP2bone morphogenetic protein 2 | Dažnai (30–79%) | 1 ligoje |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Dažnai (30–79%) | 1 ligoje |
| CCDC47coiled-coil domain containing 47 | Dažnai (30–79%) | 1 ligoje |
| CHAMP1chromosome alignment maintaining phosphoprotein 1 | Dažnai (30–79%) | 1 ligoje |
| CREBBPCREB binding lysine acetyltransferase | Dažnai (30–79%) | 3 ligose |
| CTSKcathepsin K | Dažnai (30–79%) | 1 ligoje |
| DNA2DNA replication helicase/nuclease 2 | Dažnai (30–79%) | 2 ligose |
| DVL1dishevelled segment polarity protein 1 | Dažnai (30–79%) | 1 ligoje |
| EDN1endothelin 1 | Dažnai (30–79%) | 1 ligoje |
| EP300EP300 lysine acetyltransferase | Dažnai (30–79%) | 2 ligose |
| EXOC2exocyst complex component 2 | Dažnai (30–79%) | 1 ligoje |
| FGFR3fibroblast growth factor receptor 3 | Dažnai (30–79%) | 1 ligoje |
| GNAI3G protein subunit alpha i3 | Dažnai (30–79%) | 1 ligoje |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Dažnai (30–79%) | 1 ligoje |
| GRHL3grainyhead like transcription factor 3 | Dažnai (30–79%) | 1 ligoje |
| GUSBglucuronidase beta | Dažnai (30–79%) | 1 ligoje |
| KCNK3potassium two pore domain channel subfamily K member 3 | Dažnai (30–79%) | 1 ligoje |
| MOGmyelin oligodendrocyte glycoprotein | Dažnai (30–79%) | 1 ligoje |
| NFIXnuclear factor I X | Dažnai (30–79%) | 1 ligoje |
| NGLY1N-glycanase 1 | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 52 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| NOTCH3notch receptor 3 | Dažnai (30–79%) | 1 ligoje |
| PLCB4phospholipase C beta 4 | Dažnai (30–79%) | 1 ligoje |
| POGZpogo transposable element derived with ZNF domain | Dažnai (30–79%) | 2 ligose |
| PRKAR1Bprotein kinase cAMP-dependent type I regulatory subunit beta | Dažnai (30–79%) | 1 ligoje |
| PRR12proline rich 12 | Dažnai (30–79%) | 1 ligoje |
| PTH1Rparathyroid hormone 1 receptor | Dažnai (30–79%) | 1 ligoje |
| RNH1ribonuclease/angiogenin inhibitor 1 | Dažnai (30–79%) | 1 ligoje |
| TGFBR1transforming growth factor beta receptor 1 | Dažnai (30–79%) | 1 ligoje |
| UBBubiquitin B | Dažnai (30–79%) | 1 ligoje |
| ADAMTSL2ADAMTS like 2 | Kartais (5–29%) | 1 ligoje |
| ARCN1archain 1 coat protein complex I subunit delta | Kartais (5–29%) | 1 ligoje |
| BICD2BICD cargo adaptor 2 | Kartais (5–29%) | 1 ligoje |
| CAPRIN1cell cycle associated protein 1 | Kartais (5–29%) | 1 ligoje |
| CDC42BPBCDC42 binding protein kinase beta | Kartais (5–29%) | 1 ligoje |
| CNBPCCHC-type zinc finger nucleic acid binding protein | Kartais (5–29%) | 1 ligoje |
| CRELD1CRELD disulfide isomerase 1 | Kartais (5–29%) | 1 ligoje |
| DDB1damage specific DNA binding protein 1 | Kartais (5–29%) | 1 ligoje |
| DHRSXdehydrogenase/reductase X-linked | Kartais (5–29%) | 1 ligoje |
| DPH5diphthamide biosynthesis 5 | Kartais (5–29%) | 1 ligoje |
| FBN1fibrillin 1 | Kartais (5–29%) | 1 ligoje |
| GRB10growth factor receptor bound protein 10 | Kartais (5–29%) | 1 ligoje |
| GRIN1glutamate ionotropic receptor NMDA type subunit 1 | Kartais (5–29%) | 1 ligoje |
| H4C5H4 clustered histone 5 | Kartais (5–29%) | 1 ligoje |
| HNRNPCheterogeneous nuclear ribonucleoprotein C | Kartais (5–29%) | 1 ligoje |
| LRPPRCleucine rich pentatricopeptide repeat containing | Kartais (5–29%) | 1 ligoje |
| LTBP3latent transforming growth factor beta binding protein 3 | Kartais (5–29%) | 1 ligoje |
| MAGEL2MAGE family member L2 | Kartais (5–29%) | 4 ligose |
| MCM3APminichromosome maintenance complex component 3 associated protein | Kartais (5–29%) | 1 ligoje |
| NACC1nucleus accumbens associated 1 | Kartais (5–29%) | 1 ligoje |
| NDNnecdin, MAGE family member | Kartais (5–29%) | 3 ligose |
| NONOnon-POU domain containing octamer binding | Kartais (5–29%) | 1 ligoje |
| OCA2OCA2 melanosomal transmembrane protein | Kartais (5–29%) | 3 ligose |
| PIGTphosphatidylinositol glycan anchor biosynthesis class T | Kartais (5–29%) | 1 ligoje |
| RAB11BRAB11B, member RAS oncogene family | Kartais (5–29%) | 1 ligoje |
| RECQL4RecQ like helicase 4 | Kartais (5–29%) | 1 ligoje |
| SATB2SATB homeobox 2 | Kartais (5–29%) | 1 ligoje |
| SH3BP2SH3 domain binding protein 2 | Kartais (5–29%) | 1 ligoje |
| SIM1SIM bHLH transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| SKISKI proto-oncogene | Kartais (5–29%) | 1 ligoje |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Kartais (5–29%) | 3 ligose |
| TERTtelomerase reverse transcriptase | Kartais (5–29%) | 1 ligoje |
| TNNT1troponin T1, slow skeletal type | Kartais (5–29%) | 1 ligoje |
| ZFXzinc finger protein X-linked | Kartais (5–29%) | 1 ligoje |
| ZMYM2zinc finger MYM-type containing 2 | Kartais (5–29%) | 1 ligoje |
| ZNF462zinc finger protein 462 | Kartais (5–29%) | 1 ligoje |
| ACBD6acyl-CoA binding domain containing 6 | Retai (1–4 %) | 1 ligoje |
| CA2carbonic anhydrase 2 | Retai (1–4 %) | 1 ligoje |
| HRASHRas proto-oncogene, GTPase | Neužfiksuota | 1 ligoje |
| IDSiduronate 2-sulfatase | Neužfiksuota | 1 ligoje |
| IDUAalpha-L-iduronidase | Neužfiksuota | 2 ligose |
| PCGF2polycomb group ring finger 2 | Neužfiksuota | 1 ligoje |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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