Traits

Traits linked to FOXG1

forkhead box G1

The Human Phenotype Ontology links 101 traits to FOXG1, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	Cât de frecvent apare
Absent speech development	Întotdeauna
Delayed ability to sit	Întotdeauna
Delayed ability to walk	Întotdeauna
Delayed speech and language development	Întotdeauna
Global developmental delay	Întotdeauna
Intellectual disability, severe	Întotdeauna
Poor social interactions	Întotdeauna
Seizure affecting one half of brain	Întotdeauna
Simplified gyral pattern	Întotdeauna
Underdeveloped frontal lobe	Întotdeauna
Encephalopathy	Foarte des (80–99%)
Epilepsy	Foarte des (80–99%)
Loss of developmental milestones	Foarte des (80–99%)
Repetitive movements	Foarte des (80–99%)
Underdevelopment of part of brain called corpus callosum	Foarte des (80–99%)
Abnormality of coordination	Des (30–79%)
Agenesis of corpus callosum	Des (30–79%)
Decreased reflex response	Des (30–79%)
Difficulty sleeping	Des (30–79%)
EEG abnormality	Des (30–79%)
EEG with multifocal slow activity	Des (30–79%)
Inappropriate crying	Des (30–79%)
Intellectual disability	Des (30–79%)
Irritability	Des (30–79%)
Teeth grinding	Des (30–79%)
Abnormal corpus callosum morphology	Uneori (5–29%)
Abnormal gait	Uneori (5–29%)
Abnormal myelination	Uneori (5–29%)
Ataxia	Uneori (5–29%)
Attention deficit	Uneori (5–29%)
Autism	Uneori (5–29%)
Behavioral abnormality	Uneori (5–29%)
Brain degeneration	Uneori (5–29%)
Degeneration of cerebrum	Uneori (5–29%)
Delayed CNS myelination	Uneori (5–29%)
Diminished deep tendon reflex	Uneori (5–29%)
Disorder of involuntary muscle movements	Uneori (5–29%)
Fewer and broader ridges in brain	Uneori (5–29%)
Hypsarrhythmia	Uneori (5–29%)
Impulsivity	Uneori (5–29%)
Involuntary movements	Uneori (5–29%)
Jerking	Uneori (5–29%)
Mental deterioration	Uneori (5–29%)
Tremor	Uneori (5–29%)
Unsteady walk	Uneori (5–29%)
Repeated seizures without recovery between them	Rar (1–4%)
Apraxia	Neînregistrat
Chorea	Neînregistrat
Dystonia	Neînregistrat
Involuntary writhing movements in fingers, hands, toes, and feet	Neînregistrat
Motor delay	Neînregistrat
Poor eye contact	Neînregistrat
Tongue thrusting	Neînregistrat

Abnormality of head or neck

Trait	Cât de frecvent apare
Progressively abnormally small cranium	Întotdeauna
Abnormally small head	Foarte des (80–99%)
Bulbous nose	Foarte des (80–99%)
Depressed nasal bridge	Foarte des (80–99%)
Drooping lower lip	Foarte des (80–99%)
Eye folds	Foarte des (80–99%)
Tented mouth	Foarte des (80–99%)
Abnormally large tongue	Des (30–79%)
Big lower jaw	Des (30–79%)
Downward slanting of the opening between the eyelids	Des (30–79%)
Excessive salivation	Des (30–79%)
Fullness of eyelids	Des (30–79%)
Narrow opening between the eyelids	Des (30–79%)
Prominent metopic ridge	Des (30–79%)
Short nose	Des (30–79%)
Smooth philtrum	Des (30–79%)
Failure of development of between one and six teeth	Uneori (5–29%)
High forehead	Uneori (5–29%)
Drooling	Neînregistrat
Midface retrusion	Neînregistrat
Thin red part of the upper lip	Neînregistrat

Abnormality of the musculoskeletal system

Trait	Cât de frecvent apare
Generalized decreased muscle tone	Întotdeauna
Low muscle tone	Întotdeauna
Hunched back	Des (30–79%)
Involuntary muscle stiffness, contraction, or spasm	Des (30–79%)
Scoliosis	Des (30–79%)
Poor head control	Uneori (5–29%)
Rigidity	Uneori (5–29%)
Low muscle tone, in neonatal onset	Neînregistrat

Abnormality of the eye

Trait	Cât de frecvent apare
Drooping upper eyelid	Uneori (5–29%)
Involuntary, rapid, rhythmic eye movements	Uneori (5–29%)
Abnormal involuntary eye movements	Rar (1–4%)
Abnormality of vision	Rar (1–4%)
Optic atrophy	Rar (1–4%)
Retina degeneration	Rar (1–4%)

Abnormality of limbs

Trait	Cât de frecvent apare
Increased muscle tone of arm or leg	Rar (1–4%)
Club feet	Neînregistrat
Dropped arches	Neînregistrat

Abnormality of the digestive system

Trait	Cât de frecvent apare
Acid reflux	Foarte des (80–99%)
Feeding difficulties	Foarte des (80–99%)
Constipation	Neînregistrat

Growth abnormality

Trait	Cât de frecvent apare
Growth delay	Foarte des (80–99%)
Faltering weight	Des (30–79%)
Short stature	Uneori (5–29%)

Abnormality of the ear

Trait	Cât de frecvent apare
Abnormal antihelix morphology	Foarte des (80–99%)
Prominent ear	Foarte des (80–99%)

Abnormality of prenatal development or birth

Trait	Cât de frecvent apare
Less than 10 fetal movements in 12 hours	Uneori (5–29%)

Abnormality of the respiratory system

Trait	Cât de frecvent apare
Aspiration	Des (30–79%)

Cât de frecvent apare în rândul persoanelor cu una dintre afecțiunile asociate genei, cel mai des întâlnit dintre acestea, conform Human Phenotype Ontology. Aceste pagini descriu trăsături și cercetările din spatele lor; ele nu reprezintă un diagnostic, iar pentru simptome trebuie să vă adresați medicului sau consilierului genetic.

De unde provin aceste informații

The Human Phenotype Ontology, release 2026-09-01: the traits linked to FOXG1 and how often each is seen. Find out more at hpo.jax.org.

Un test. Răspunsuri pentru o viață.

De la 449 $Livrare gratuită · Rezultate în 6–8 săptămâni

Comandați Genome Test-ul meu