Trait
Low levels of amniotic fluid
Clinical name: Oligohydramnios
Diminished amniotic fluid volume in pregnancy.
Summary
- Also called
- Maternal oligohydramnios
- Body system
- Abnormality of prenatal development or birth
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Low levels of amniotic fluid, and the rest of your genome, with one test.
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Get my Genome Test209 genes linked to Low levels of amniotic fluid
Changes in these genes cause rare conditions in which Low levels of amniotic fluid is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BNIP1BCL2 interacting protein 1 | Always | In 1 condition |
| CEP55centrosomal protein 55 | Always | In 1 condition |
| COX14cytochrome c oxidase assembly factor COX14 | Always | In 1 condition |
| DALRD3DALR anticodon binding domain containing 3 | Always | In 1 condition |
| EFEMP2EGF-like fibulin extracellular matrix protein 2 | Always | In 1 condition |
| EXOC3L2exocyst complex component 3 like 2 | Always | In 1 condition |
| FARSAphenylalanyl-tRNA synthetase subunit alpha | Always | In 1 condition |
| FARSBphenylalanyl-tRNA synthetase subunit beta | Always | In 1 condition |
| IARS1isoleucyl-tRNA synthetase 1 | Always | In 2 conditions |
| LARS2leucyl-tRNA synthetase 2, mitochondrial | Always | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| MED16mediator complex subunit 16 | Always | In 1 condition |
| MYH11myosin heavy chain 11 | Always | In 1 condition |
| MYL9myosin light chain 9 | Always | In 1 condition |
| NDUFB7NADH:ubiquinone oxidoreductase subunit B7 | Always | In 1 condition |
| PDX1pancreatic and duodenal homeobox 1 | Always | In 1 condition |
| RCC1regulator of chromosome condensation 1 | Always | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Always | In 1 condition |
| SLC25A24solute carrier family 25 member 24 | Always | In 1 condition |
| TMEM231transmembrane protein 231 | Always | In 2 conditions |
| TRA2Btransformer 2 beta homolog | Always | In 1 condition |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Always | In 1 condition |
| UQCC2ubiquinol-cytochrome c reductase complex assembly factor 2 | Always | In 1 condition |
| WNT4Wnt family member 4 | Always | In 2 conditions |
| ZMPSTE24zinc metallopeptidase STE24 | Always | In 1 condition |
| FGF20fibroblast growth factor 20 | Very often (80–99%) | In 1 condition |
| GFRA1GDNF family receptor alpha 1 | Very often (80–99%) | In 1 condition |
| GREB1LGREB1 like retinoic acid receptor coactivator | Very often (80–99%) | In 1 condition |
| HYMAIhydatidiform mole associated and imprinted | Very often (80–99%) | In 1 condition |
| ITGA8integrin subunit alpha 8 | Very often (80–99%) | In 2 conditions |
| PLAGL1PLAG1 like zinc finger 1 | Very often (80–99%) | In 1 condition |
| RETret proto-oncogene | Very often (80–99%) | In 2 conditions |
| TCTN3tectonic family member 3 | Very often (80–99%) | In 2 conditions |
| TMEM70transmembrane protein 70 | Very often (80–99%) | In 2 conditions |
| WNT9BWnt family member 9B | Very often (80–99%) | In 1 condition |
| ACTG2actin gamma 2, smooth muscle | Often (30–79%) | In 1 condition |
| ALG8ALG8 alpha-1,3-glucosyltransferase | Often (30–79%) | In 2 conditions |
| ALX4ALX homeobox 4 | Often (30–79%) | In 2 conditions |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Often (30–79%) | In 1 condition |
| B9D1B9 domain containing 1 | Often (30–79%) | In 1 condition |
Show 169 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| B9D2B9 domain containing 2 | Often (30–79%) | In 1 condition |
| BIN1bridging integrator 1 | Often (30–79%) | In 1 condition |
| C1QBPcomplement C1q binding protein | Often (30–79%) | In 1 condition |
| CC2D2Acoiled-coil and C2 domain containing 2A | Often (30–79%) | In 1 condition |
| CDKN1Ccyclin dependent kinase inhibitor 1C | Often (30–79%) | In 1 condition |
| CEP290centrosomal protein 290 | Often (30–79%) | In 1 condition |
| CERT1ceramide transporter 1 | Often (30–79%) | In 1 condition |
| CHRM3cholinergic receptor muscarinic 3 | Often (30–79%) | In 2 conditions |
| CSPP1centrosome and spindle pole associated protein 1 | Often (30–79%) | In 1 condition |
| DEF6DEF6 guanine nucleotide exchange factor | Often (30–79%) | In 1 condition |
| DOCK6dedicator of cytokinesis 6 | Often (30–79%) | In 1 condition |
| DSTdystonin | Often (30–79%) | In 2 conditions |
| DZIP1LDAZ interacting zinc finger protein 1 like | Often (30–79%) | In 1 condition |
| EBF3EBF transcription factor 3 | Often (30–79%) | In 1 condition |
| FREM2FRAS1 related extracellular matrix 2 | Often (30–79%) | In 1 condition |
| GRIP1glutamate receptor interacting protein 1 | Often (30–79%) | In 1 condition |
| H19H19 imprinted maternally expressed transcript | Often (30–79%) | In 1 condition |
| HBA1hemoglobin subunit alpha 1 | Often (30–79%) | In 1 condition |
| HBA2hemoglobin subunit alpha 2 | Often (30–79%) | In 1 condition |
| HMGA2high mobility group AT-hook 2 | Often (30–79%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Often (30–79%) | In 1 condition |
| IGF2insulin like growth factor 2 | Often (30–79%) | In 3 conditions |
| KIF14kinesin family member 14 | Often (30–79%) | In 1 condition |
| LAMB2laminin subunit beta 2 | Often (30–79%) | In 2 conditions |
| LIFRLIF receptor subunit alpha | Often (30–79%) | In 2 conditions |
| MKS1MKS transition zone complex subunit 1 | Often (30–79%) | In 2 conditions |
| MTO1mitochondrial tRNA translation optimization 1 | Often (30–79%) | In 1 condition |
| NEK8NIMA related kinase 8 | Often (30–79%) | In 2 conditions |
| NOTCH3notch receptor 3 | Often (30–79%) | In 1 condition |
| NPHP3nephrocystin 3 | Often (30–79%) | In 4 conditions |
| PAX2paired box 2 | Often (30–79%) | In 1 condition |
| PBX1PBX homeobox 1 | Often (30–79%) | In 2 conditions |
| PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin | Often (30–79%) | In 2 conditions |
| PLAG1PLAG1 zinc finger | Often (30–79%) | In 1 condition |
| RBM10RNA binding motif protein 10 | Often (30–79%) | In 1 condition |
| RNF2ring finger protein 2 | Often (30–79%) | In 1 condition |
| RPGRIP1RPGR interacting protein 1 | Often (30–79%) | In 1 condition |
| RPGRIP1LRPGRIP1 like | Often (30–79%) | In 1 condition |
| SFXN4sideroflexin 4 | Often (30–79%) | In 1 condition |
| SV2Asynaptic vesicle glycoprotein 2A | Often (30–79%) | In 1 condition |
| SZT2SZT2 subunit of KICSTOR complex | Often (30–79%) | In 1 condition |
| TCTN1tectonic family member 1 | Often (30–79%) | In 1 condition |
| TCTN2tectonic family member 2 | Often (30–79%) | In 1 condition |
| TMEM107transmembrane protein 107 | Often (30–79%) | In 1 condition |
| TMEM216transmembrane protein 216 | Often (30–79%) | In 1 condition |
| TMEM237transmembrane protein 237 | Often (30–79%) | In 1 condition |
| TMEM67transmembrane protein 67 | Often (30–79%) | In 1 condition |
| TPI1triosephosphate isomerase 1 | Often (30–79%) | In 1 condition |
| TRIP4thyroid hormone receptor interactor 4 | Often (30–79%) | In 1 condition |
| TXNDC15thioredoxin domain containing 15 | Often (30–79%) | In 2 conditions |
| ALBalbumin | Sometimes (5–29%) | In 2 conditions |
| ALG9ALG9 alpha-1,2-mannosyltransferase | Sometimes (5–29%) | In 2 conditions |
| ASCL1achaete-scute family bHLH transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| ATN1atrophin 1 | Sometimes (5–29%) | In 1 condition |
| B3GALT6beta-1,3-galactosyltransferase 6 | Sometimes (5–29%) | In 1 condition |
| BRCA1BRCA1 DNA repair associated | Sometimes (5–29%) | In 1 condition |
| BRCA2BRCA2 DNA repair associated | Sometimes (5–29%) | In 1 condition |
| BRIP1BRCA1 interacting DNA helicase 1 | Sometimes (5–29%) | In 1 condition |
| CA2carbonic anhydrase 2 | Sometimes (5–29%) | In 1 condition |
| CDC42BPBCDC42 binding protein kinase beta | Sometimes (5–29%) | In 1 condition |
| CLTCL1clathrin heavy chain like 1 | Sometimes (5–29%) | In 1 condition |
| COG5component of oligomeric golgi complex 5 | Sometimes (5–29%) | In 1 condition |
| COL25A1collagen type XXV alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| CPT2carnitine palmitoyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| CRELD1CRELD disulfide isomerase 1 | Sometimes (5–29%) | In 1 condition |
| DDX6DEAD-box helicase 6 | Sometimes (5–29%) | In 1 condition |
| DHPSdeoxyhypusine synthase | Sometimes (5–29%) | In 1 condition |
| DPF2double PHD fingers 2 | Sometimes (5–29%) | In 1 condition |
| DSPdesmoplakin | Sometimes (5–29%) | In 1 condition |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Sometimes (5–29%) | In 2 conditions |
| ELFN1extracellular leucine rich repeat and fibronectin type III domain containing 1 | Sometimes (5–29%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Sometimes (5–29%) | In 1 condition |
| ERGIC1endoplasmic reticulum-golgi intermediate compartment 1 | Sometimes (5–29%) | In 1 condition |
| FAAP100FA core complex associated protein 100 | Sometimes (5–29%) | In 1 condition |
| FANCAFA complementation group A | Sometimes (5–29%) | In 1 condition |
| FANCBFA complementation group B | Sometimes (5–29%) | In 1 condition |
| FANCCFA complementation group C | Sometimes (5–29%) | In 1 condition |
| FANCD2FA complementation group D2 | Sometimes (5–29%) | In 1 condition |
| FANCEFA complementation group E | Sometimes (5–29%) | In 1 condition |
| FANCFFA complementation group F | Sometimes (5–29%) | In 1 condition |
| FANCGFA complementation group G | Sometimes (5–29%) | In 1 condition |
| FANCIFA complementation group I | Sometimes (5–29%) | In 1 condition |
| FANCLFA complementation group L | Sometimes (5–29%) | In 1 condition |
| FANCMFA complementation group M | Sometimes (5–29%) | In 1 condition |
| FBXO22F-box protein 22 | Sometimes (5–29%) | In 1 condition |
| FHfumarate hydratase | Sometimes (5–29%) | In 1 condition |
| FILIP1filamin A interacting protein 1 | Sometimes (5–29%) | In 1 condition |
| FRA10AC1FRA10A associated CGG repeat 1 | Sometimes (5–29%) | In 1 condition |
| FXR1FMR1 autosomal homolog 1 | Sometimes (5–29%) | In 2 conditions |
| GATA6GATA binding protein 6 | Sometimes (5–29%) | In 1 condition |
| GMPPBGDP-mannose pyrophosphorylase B | Sometimes (5–29%) | In 1 condition |
| GNB2G protein subunit beta 2 | Sometimes (5–29%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Sometimes (5–29%) | In 1 condition |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Sometimes (5–29%) | In 1 condition |
| HIVEP2HIVEP zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| HNF1BHNF1 homeobox B | Sometimes (5–29%) | In 1 condition |
| HS2ST1heparan sulfate 2-O-sulfotransferase 1 | Sometimes (5–29%) | In 1 condition |
| INPPL1inositol polyphosphate phosphatase like 1 | Sometimes (5–29%) | In 1 condition |
| JUPjunction plakoglobin | Sometimes (5–29%) | In 1 condition |
| LHX1LIM homeobox 1 | Sometimes (5–29%) | In 1 condition |
| MAD2L2mitotic arrest deficient 2 like 2 | Sometimes (5–29%) | In 1 condition |
| MAGEL2MAGE family member L2 | Sometimes (5–29%) | In 1 condition |
| MKRN3makorin ring finger protein 3 | Sometimes (5–29%) | In 1 condition |
| MYH3myosin heavy chain 3 | Sometimes (5–29%) | In 2 conditions |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Sometimes (5–29%) | In 1 condition |
| NALCNsodium leak channel, non-selective | Sometimes (5–29%) | In 1 condition |
| NDUFA6NADH:ubiquinone oxidoreductase subunit A6 | Sometimes (5–29%) | In 1 condition |
| NEK9NIMA related kinase 9 | Sometimes (5–29%) | In 1 condition |
| NPAP1nuclear pore associated protein 1 | Sometimes (5–29%) | In 1 condition |
| PALB2partner and localizer of BRCA2 | Sometimes (5–29%) | In 1 condition |
| PGAP2post-GPI attachment to proteins 2 | Sometimes (5–29%) | In 1 condition |
| PGAP3post-GPI attachment to proteins phospholipase 3 | Sometimes (5–29%) | In 1 condition |
| PHOX2Bpaired like homeobox 2B | Sometimes (5–29%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Sometimes (5–29%) | In 1 condition |
| PIGOphosphatidylinositol glycan anchor biosynthesis class O | Sometimes (5–29%) | In 1 condition |
| PIGVphosphatidylinositol glycan anchor biosynthesis class V | Sometimes (5–29%) | In 1 condition |
| PIGWphosphatidylinositol glycan anchor biosynthesis class W | Sometimes (5–29%) | In 1 condition |
| PIGYphosphatidylinositol glycan anchor biosynthesis class Y | Sometimes (5–29%) | In 1 condition |
| PUF60poly(U) binding splicing factor 60 | Sometimes (5–29%) | In 1 condition |
| PWAR1Prader Willi/Angelman region RNA 1 | Sometimes (5–29%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Sometimes (5–29%) | In 1 condition |
| RAD51RAD51 recombinase | Sometimes (5–29%) | In 1 condition |
| RAD51CRAD51 paralog C | Sometimes (5–29%) | In 1 condition |
| RFWD3ring finger and WD repeat domain 3 | Sometimes (5–29%) | In 1 condition |
| RHAGRh associated glycoprotein | Sometimes (5–29%) | In 1 condition |
| RHCERh blood group CcEe antigens | Sometimes (5–29%) | In 1 condition |
| RHDRh blood group D antigen | Sometimes (5–29%) | In 1 condition |
| SATB1SATB homeobox 1 | Sometimes (5–29%) | In 1 condition |
| SCYL2SCY1 like pseudokinase 2 | Sometimes (5–29%) | In 1 condition |
| SEC61A1SEC61 translocon subunit alpha 1 | Sometimes (5–29%) | In 1 condition |
| SETD1ASET domain containing 1A, histone lysine methyltransferase | Sometimes (5–29%) | In 1 condition |
| SLC35A2solute carrier family 35 member A2 | Sometimes (5–29%) | In 1 condition |
| SLX4SLX4 structure-specific endonuclease subunit | Sometimes (5–29%) | In 1 condition |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Sometimes (5–29%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Sometimes (5–29%) | In 1 condition |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Sometimes (5–29%) | In 1 condition |
| TBCKTBC1 domain containing kinase | Sometimes (5–29%) | In 2 conditions |
| UBE2Aubiquitin conjugating enzyme E2 A | Sometimes (5–29%) | In 1 condition |
| UBE2Tubiquitin conjugating enzyme E2 T | Sometimes (5–29%) | In 1 condition |
| VIPAS39VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog | Sometimes (5–29%) | In 1 condition |
| VPS33BVPS33B late endosome and lysosome associated | Sometimes (5–29%) | In 2 conditions |
| WBP4WW domain binding protein 4 | Sometimes (5–29%) | In 1 condition |
| WSB2WD repeat and SOCS box containing 2 | Sometimes (5–29%) | In 1 condition |
| XRCC2X-ray repair cross complementing 2 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| BNC2basonuclin zinc finger protein 2 | Rarely (1–4%) | In 1 condition |
| DONSONDNA replication fork stabilization factor DONSON | Rarely (1–4%) | In 2 conditions |
| GLI3GLI family zinc finger 3 | Rarely (1–4%) | In 1 condition |
| ACEangiotensin I converting enzyme | Not recorded | In 1 condition |
| AGTangiotensinogen | Not recorded | In 1 condition |
| AGTR1angiotensin II receptor type 1 | Not recorded | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Not recorded | In 1 condition |
| BMPERBMP binding endothelial regulator | Not recorded | In 1 condition |
| BUB1BBUB1 mitotic checkpoint serine/threonine kinase B | Not recorded | In 1 condition |
| COQ7coenzyme Q7, hydroxylase | Not recorded | In 1 condition |
| EXOSC9exosome component 9 | Not recorded | In 1 condition |
| FBLN5fibulin 5 | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| HSPA9heat shock protein family A (Hsp70) member 9 | Not recorded | In 1 condition |
| INVSinversin | Not recorded | In 1 condition |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Not recorded | In 1 condition |
| MYLKmyosin light chain kinase | Not recorded | In 1 condition |
| OSGEPO-sialoglycoprotein endopeptidase | Not recorded | In 1 condition |
| PORcytochrome p450 oxidoreductase | Not recorded | In 1 condition |
| RENrenin | Not recorded | In 1 condition |
| RNU4ATACRNA, U4atac small nuclear | Not recorded | In 1 condition |
| SEC24DSEC24 homolog D, COPII component | Not recorded | In 1 condition |
| TALDO1transaldolase 1 | Not recorded | In 1 condition |
| WDR73WD repeat domain 73 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
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