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Gene

DPF2

double PHD fingers 2

Summary

Cytogenetic location
11q13.1
Coordinates
Chromosome 11: 65,333,852–65,354,262 (GRCh38)
Exons
11 exons across 20.4 kb
Protein
391 amino acids
Also known as
ubi-d4, BAF45d, SMARCG2
Previous symbols
REQ
MANE Select transcript
ENST00000528416.6NM_006268.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DPF2 yet. The test sequences your whole genome, so your data includes it all the same.

How DPF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where DPF2 sits. DPF2 and 45 genes near it on chromosome 11, from 64,844,057 to 65,844,056.Chromosome 1111q13.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2565 Mb65.2 Mb65.4 Mb65.6 Mb65.8 MbCDC42BPG: 64,823,051–64,844,735, reverse strandCDC42BPGEHD1: 64,851,642–64,888,372, reverse strandEHD1ATG2A: 64,894,531–64,917,249, reverse strandATG2APPP2R5B: 64,917,553–64,934,480, forward strandPPP2R5BGPHA2: 64,934,471–64,935,894, reverse strandGPHA2MAJIN: 64,937,517–64,972,113, reverse strandMAJINBATF2: 64,987,945–64,997,018, reverse strandARL2: 65,013,735–65,024,328, forward strandARL2-SNX15: 65,014,182–65,040,570, forward strandARL2-SNX15SNX15: 65,027,404–65,040,578, forward strandSNX15SAC3D1: 65,040,897–65,047,320, forward strandSAC3D1NAALADL1: 65,044,818–65,058,558, reverse strandNAALADL1CDCA5: 65,066,299–65,084,164, reverse strandZFPL1: 65,084,210–65,088,409, forward strandCATSPERH: 65,084,974–65,089,375, reverse strandVPS51: 65,089,324–65,111,862, forward strandTM7SF2: 65,111,845–65,116,677, forward strandZNHIT2: 65,116,403–65,117,701, reverse strandZNHIT2FAU: 65,120,182–65,122,221, reverse strandFAUSYVN1: 65,121,780–65,146,912, reverse strandSYVN1MRPL49: 65,122,183–65,127,371, forward strandMRPL49SPDYC: 65,166,137–65,173,380, forward strandSPDYCCAPN1: 65,180,566–65,212,006, forward strandCAPN1POLA2: 65,261,835–65,305,959, forward strandPOLA2: 65,261,928–65,326,543, forward strandCDC42EP2: 65,298,955–65,322,662, forward strandCDC42EP2DPF2: 65,333,852–65,354,262, forward strandDPF2TIGD3: 65,354,746–65,357,613, forward strandTIGD3SLC25A45: 65,375,186–65,384,550, reverse strandSLC25A45FRMD8: 65,386,592–65,413,526, forward strandFRMD8SCYL1: 65,525,044–65,538,711, forward strandSCYL1LTBP3: 65,538,556–65,558,930, reverse strandLTBP3ZNRD2: 65,570,459–65,574,203, forward strandZNRD2FAM89B: 65,572,349–65,574,199, forward strandFAM89BEHBP1L1: 65,575,943–65,594,089, forward strandKCNK7: 65,592,836–65,595,996, reverse strandMAP3K11: 65,597,149–65,615,382, reverse strandPCNX3: 65,615,742–65,637,441, forward strandPCNX3SIPA1: 65,638,086–65,650,930, forward strandSIPA1RELA: 65,653,599–65,663,138, reverse strandRELAKAT5: 65,711,992–65,719,604, forward strandKAT5RNASEH2C: 65,713,901–65,720,988, reverse strandRNASEH2CAP5B1: 65,772,723–65,781,708, reverse strandAP5B1OVOL1: 65,786,714–65,797,219, forward strandOVOL1CFL1: 65,823,022–65,862,026, reverse strandCFL1SNX32: 65,833,664–65,856,896, forward strandSNX32Diagram of DPF2: 11 exons on the forward strand of chromosome 11Exon 7: 1 known disease-causing siteExon 8: 2 known disease-causing sitesExon 9: 2 known disease-causing sitesExon 10: 6 known disease-causing sitesExon 1: 65,333,852–65,333,918, 67 basesExon 2: 65,340,385–65,340,545, 161 basesExon 3: 65,340,966–65,341,073, 108 basesExon 4: 65,341,399–65,341,562, 164 basesExon 5: 65,343,745–65,343,837, 93 basesExon 6: 65,343,991–65,344,069, 79 basesExon 7: 65,345,666–65,345,803, 138 basesExon 8: 65,345,930–65,346,058, 129 basesExon 9: 65,346,247–65,346,359, 113 basesExon 10: 65,348,850–65,348,931, 82 basesExon 11: 65,351,683–65,354,262, 2,580 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 20.4 kb; 1,176 of those bases code for the protein.

How a genome test reads DPF2

13

positions in DPF2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 20.4 kb of DPF2, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DPF2 gene: double PHD fingers 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/dpf2

Vancouver

Dante Labs. DPF2 gene: double PHD fingers 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dpf2

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