Skip to content
Use your HSA or FSA funds

Gene

CRELD1

CRELD disulfide isomerase 1

Summary

Cytogenetic location
3p25.3
Coordinates
Chromosome 3: 9,933,834–9,945,406 (GRCh38)
Exons
11 exons across 11.6 kb
Protein
420 amino acids
Also known as
CIRRIN
Previous symbols
AVSD2
MANE Select transcript
ENST00000452070.6NM_001077415.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CRELD1 yet. The test sequences your whole genome, so your data includes it all the same.

How CRELD1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where CRELD1 sits. CRELD1 and 30 genes near it on chromosome 3, from 9,439,620 to 10,439,619.Chromosome 33p25.3p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q299.6 Mb9.8 Mb10 Mb10.2 Mb10.4 MbSETD5: 9,397,609–9,479,240, forward strandSETD5LHFPL4: 9,498,361–9,553,862, reverse strandLHFPL4MTMR14: 9,649,307–9,702,394, forward strandMTMR14CPNE9: 9,703,691–9,729,908, forward strandCPNE9BRPF1: 9,731,726–9,748,019, forward strandBRPF1OGG1: 9,749,938–9,791,067, forward strandOGG1CAMK1: 9,757,341–9,770,606, reverse strandTADA3: 9,779,964–9,793,011, reverse strandARPC4: 9,792,484–9,807,704, forward strandARPC4ARPC4-TTLL3: 9,793,082–9,835,401, forward strandARPC4-TTLL3TTLL3: 9,808,086–9,856,087, forward strandTTLL3RPUSD3: 9,831,633–9,844,602, reverse strandRPUSD3CIDEC: 9,864,169–9,891,008, reverse strandCIDECJAGN1: 9,890,569–9,894,349, forward strandIL17RE: 9,902,612–9,916,402, forward strandIL17RC: 9,917,040–9,933,630, forward strandIL17RC: 9,917,116–9,945,385, forward strandCRELD1: 9,933,834–9,945,406, forward strandCRELD1PRRT3: 9,939,450–9,952,442, reverse strandPRRT3EMC3: 9,957,217–10,011,202, reverse strandEMC3FANCD2: 10,026,370–10,101,937, forward strandFANCD2FANCD2OS: 10,081,317–10,108,290, reverse strandFANCD2OSBRK1: 10,115,590–10,135,082, forward strandBRK1VHL: 10,141,764–10,153,676, forward strandVHLIRAK2: 10,164,862–10,243,756, forward strandIRAK2TATDN2: 10,248,023–10,281,218, forward strandTATDN2: 10,249,042–10,249,366, forward strand: 10,249,372–10,285,796, forward strandGHRL: 10,285,666–10,292,959, reverse strandGHRLSEC13: 10,293,131–10,321,207, reverse strandSEC13ATP2B2: 10,324,023–10,708,060, reverse strandATP2B2Diagram of CRELD1: 11 exons on the forward strand of chromosome 3Exon 3: 1 known disease-causing siteExon 6: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 1: 9,933,834–9,933,920, 87 basesExon 2: 9,934,420–9,934,612, 193 basesExon 3: 9,934,835–9,934,917, 83 basesExon 4: 9,937,562–9,937,672, 111 basesExon 5: 9,938,015–9,938,106, 92 basesExon 6: 9,940,850–9,941,026, 177 basesExon 7: 9,941,111–9,941,206, 96 basesExon 8: 9,942,813–9,942,896, 84 basesExon 9: 9,943,077–9,943,172, 96 basesExon 10: 9,943,381–9,943,515, 135 basesExon 11: 9,944,365–9,945,406, 1,042 bases12345678910115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 11.6 kb; 1,263 of those bases code for the protein.

How a genome test reads CRELD1

9

positions in CRELD1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 11.6 kb of CRELD1, introns included, not only the 2.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CRELD1 gene: CRELD disulfide isomerase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/creld1

Vancouver

Dante Labs. CRELD1 gene: CRELD disulfide isomerase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/creld1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test