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Gene

NAA10

N-alpha-acetyltransferase 10, NatA catalytic subunit

Summary

Cytogenetic location
Xq28
Coordinates
Chromosome X: 153,929,225–153,935,037 (GRCh38)
Exons
8 exons across 5.8 kb
Protein
235 amino acids
Also known as
DXS707, TE2
Previous symbols
ARD1, ARD1A
MANE Select transcript
ENST00000464845.6NM_003491.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Intellectual Disability

      • One of 233 genes linked to it

        • ClinGen rates the link definitive
        • 6 GenCC submitters rate it definitive or strong

    How NAA10 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    Chromosome X, with a bracket where NAA10 sits. NAA10 and 36 genes near it on chromosome X, from 153,432,131 to 154,432,130.Chromosome XXq28p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q28153.6 Mb153.8 Mb154 Mb154.2 Mb154.4 MbTREX2: 153,444,473–153,470,592, reverse strandTREX2HAUS7: 153,447,655–153,495,529, reverse strandHAUS7BGN: 153,488,654–153,510,711, forward strandBGNATP2B3: 153,517,620–153,582,939, forward strandATP2B3CCNQ: 153,587,925–153,600,045, reverse strandCCNQDUSP9: 153,642,397–153,651,326, forward strandDUSP9PNCK: 153,669,730–153,689,033, reverse strandPNCKSLC6A8: 153,687,914–153,696,591, forward strandSLC6A8BCAP31: 153,698,006–153,725,957, reverse strandBCAP31ABCD1: 153,724,495–153,744,755, forward strandABCD1PLXNB3: 153,764,179–153,779,346, forward strandSRPK3: 153,781,001–153,785,768, forward strandSRPK3IDH3G: 153,785,735–153,794,535, reverse strandIDH3GSSR4: 153,793,516–153,798,510, forward strandSSR4PDZD4: 153,802,161–153,830,935, reverse strandPDZD4L1CAM: 153,861,511–153,886,204, reverse strandL1CAM: 153,872,221–153,909,223, reverse strandAVPR2: 153,902,531–153,907,169, forward strandAVPR2ARHGAP4: 153,907,367–153,934,999, reverse strandARHGAP4NAA10: 153,929,225–153,935,037, reverse strandNAA10RENBP: 153,935,269–153,944,688, reverse strandRENBPHCFC1: 153,946,434–153,972,427, reverse strandHCFC1TMEM187: 153,972,290–153,983,194, forward strandIRAK1: 154,010,501–154,020,650, reverse strandIRAK1MECP2: 154,021,573–154,137,103, reverse strandMECP2OPN1LW: 154,144,243–154,159,032, forward strandOPN1LWOPN1MW: 154,182,596–154,196,861, forward strandOPN1MWOPN1MW2: 154,219,756–154,233,286, forward strandOPN1MW2OPN1MW3: 154,257,582–154,271,090, forward strandOPN1MW3TEX28: 154,271,265–154,295,853, reverse strandTEX28TKTL1: 154,295,795–154,330,350, forward strandTKTL1FLNA: 154,348,524–154,374,643, reverse strandFLNAEMD: 154,379,205–154,381,574, forward strandEMDRPL10: 154,389,955–154,409,168, forward strandRPL10DNASE1L1: 154,401,236–154,412,119, reverse strandDNASE1L1TAFAZZIN: 154,409,456–154,421,726, forward strandATP6AP1: 154,428,618–154,436,517, forward strandDiagram of NAA10: 8 exons on the reverse strand of chromosome XExon 8: 4 known disease-causing sitesExon 7: 1 known disease-causing siteExon 6: 9 known disease-causing sitesExon 5: 6 known disease-causing sitesExon 4: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 2: 4 known disease-causing sitesExon 8: 153,929,225–153,930,223, 999 basesExon 7: 153,930,763–153,930,847, 85 basesExon 6: 153,932,071–153,932,115, 45 basesExon 5: 153,932,316–153,932,431, 116 basesExon 4: 153,932,539–153,932,584, 46 basesExon 3: 153,933,943–153,934,001, 59 basesExon 2: 153,934,377–153,934,475, 99 basesExon 1: 153,934,884–153,935,037, 154 bases876543215′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 1.6 kb of the gene's 5.8 kb; 708 of those bases code for the protein.

    How a genome test reads NAA10

    28

    positions in NAA10 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 5.8 kb of NAA10, introns included, not only the 1.6 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). NAA10 gene: N-alpha-acetyltransferase 10, NatA catalytic subunit. Retrieved 17 October 2026, from https://dantelabs.com/genes/naa10

    Vancouver

    Dante Labs. NAA10 gene: N-alpha-acetyltransferase 10, NatA catalytic subunit [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/naa10

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