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Gene

DONSON

DNA replication fork stabilization factor DONSON

Summary

Cytogenetic location
21q22.11
Coordinates
Chromosome 21: 33,577,551–33,588,684 (GRCh38)
Exons
10 exons across 11.1 kb
Protein
566 amino acids
Also known as
B17, C2TA, DKFZP434M035
Previous symbols
C21orf60
MANE Select transcript
ENST00000303071.10NM_017613.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DONSON yet. The test sequences your whole genome, so your data includes it all the same.

How DONSON is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 21, with a bracket where DONSON sits. DONSON and 16 genes near it on chromosome 21, from 33,083,118 to 34,083,117.Chromosome 2121q22.11p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.333.2 Mb33.4 Mb33.6 Mb33.8 Mb34 MbIFNAR2: 33,205,282–33,265,675, forward strandIFNAR2IFNAR2-IL10RB: 33,229,892–33,297,160, forward strandIFNAR2-IL10RBIL10RB: 33,265,958–33,311,420, forward strandIL10RBIFNAR1: 33,324,387–33,359,864, forward strandIFNAR1IFNGR2: 33,403,205–33,479,348, forward strandIFNGR2TMEM50B: 33,432,190–33,480,004, reverse strandTMEM50BDNAJC28: 33,485,615–33,491,753, reverse strandDNAJC28GART: 33,498,517–33,543,524, reverse strandGARTSON: 33,542,214–33,577,481, forward strandSONDONSON: 33,577,551–33,588,684, reverse strandDONSON: 33,584,687–33,931,607, reverse strandCRYZL1: 33,589,341–33,643,926, reverse strandCRYZL1ITSN1: 33,642,400–33,899,861, forward strandITSN1ATP5PO: 33,901,027–33,915,853, reverse strandATP5POMRPS6: 34,072,889–34,362,252, forward strandMRPS6SLC5A3: 34,073,509–34,106,260, forward strandSLC5A3: 34,073,509–34,143,037, forward strandDiagram of DONSON: 10 exons on the reverse strand of chromosome 21Exon 10: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 8: 3 known disease-causing sitesExon 5: 4 known disease-causing sitesExon 4: 3 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 1: 3 known disease-causing sitesExon 10: 33,577,551–33,578,444, 894 basesExon 9: 33,579,350–33,579,562, 213 basesExon 8: 33,581,302–33,581,500, 199 basesExon 7: 33,581,951–33,582,055, 105 basesExon 6: 33,582,165–33,582,246, 82 basesExon 5: 33,583,488–33,583,666, 179 basesExon 4: 33,584,590–33,584,768, 179 basesExon 3: 33,585,978–33,586,181, 204 basesExon 2: 33,587,522–33,587,602, 81 basesExon 1: 33,588,321–33,588,684, 364 bases109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 11.1 kb; 1,701 of those bases code for the protein.

How a genome test reads DONSON

20

positions in DONSON where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 11.1 kb of DONSON, introns included, not only the 2.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DONSON gene: DNA replication fork stabilization factor DONSON. Retrieved 17 October 2026, from https://dantelabs.com/genes/donson

Vancouver

Dante Labs. DONSON gene: DNA replication fork stabilization factor DONSON [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/donson

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