Skip to content
Use your HSA or FSA funds

Gene

DHPS

deoxyhypusine synthase

Summary

Cytogenetic location
19p13.13
Coordinates
Chromosome 19: 12,675,717–12,681,880 (GRCh38)
Exons
9 exons across 6.2 kb
Protein
369 amino acids
Also known as
MIG13
MANE Select transcript
ENST00000210060.12NM_001930.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DHPS yet. The test sequences your whole genome, so your data includes it all the same.

How DHPS is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where DHPS sits. DHPS and 48 genes near it on chromosome 19, from 12,178,799 to 13,178,798.Chromosome 1919p13.13p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4312.2 Mb12.4 Mb12.6 Mb12.8 Mb13 MbZNF136: 12,163,052–12,189,871, forward strandZNF136ZNF44: 12,224,686–12,294,883, reverse strandZNF44ZNF563: 12,317,477–12,333,723, reverse strandZNF563ZNF442: 12,345,944–12,365,905, reverse strandZNF442ZNF799: 12,390,016–12,401,280, reverse strandZNF799: 12,391,949–12,441,082, reverse strandZNF443: 12,429,706–12,441,021, reverse strandZNF443: 12,433,103–12,484,816, reverse strandZNF709: 12,461,184–12,513,854, reverse strandZNF709: 12,461,559–12,551,474, reverse strandZNF564: 12,524,903–12,551,542, reverse strandZNF564: 12,525,720–12,580,975, reverse strandZNF490: 12,575,832–12,640,098, reverse strandZNF791: 12,610,916–12,633,840, forward strandZNF791MAN2B1: 12,643,831–12,666,762, reverse strand: 12,643,831–12,648,397, reverse strand: 12,664,828–12,669,397, reverse strandWDR83: 12,666,802–12,675,832, forward strandWDR83WDR83OS: 12,668,065–12,669,467, reverse strand: 12,668,071–12,681,834, reverse strandDHPS: 12,675,717–12,681,880, reverse strandDHPSFBXW9: 12,687,801–12,696,659, reverse strandGNG14: 12,687,998–12,688,422, forward strandGNG14TNPO2: 12,699,111–12,724,011, reverse strandTRIR: 12,730,640–12,734,747, reverse strandTRIRGET3: 12,737,139–12,748,325, forward strandGET3BEST2: 12,751,673–12,758,458, forward strandBEST2HOOK2: 12,762,640–12,872,740, reverse strandJUNB: 12,791,486–12,793,315, forward strandJUNBPRDX2: 12,796,817–12,801,882, reverse strandPRDX2THSD8: 12,802,031–12,813,581, forward strandTHSD8RNASEH2A: 12,806,505–12,813,644, forward strandRTBDN: 12,825,477–12,838,362, reverse strandMAST1: 12,833,860–12,874,952, forward strandMAST1DNASE2: 12,875,209–12,881,595, reverse strandDNASE2KLF1: 12,884,405–12,887,201, reverse strandKLF1GCDH: 12,891,128–12,915,261, forward strandGCDHSYCE2: 12,898,786–12,919,306, reverse strandSYCE2FARSA: 12,921,138–12,934,037, reverse strandCALR: 12,938,578–12,944,525, forward strandCALRRAD23A: 12,945,716–12,953,646, forward strandGADD45GIP1: 12,950,701–12,957,333, reverse strandDAND5: 12,965,159–12,974,760, forward strandDAND5NFIX: 12,995,401–13,098,796, forward strandNFIXLYL1: 13,099,028–13,103,188, reverse strandLYL1TRMT1: 13,104,899–13,117,567, reverse strandTRMT1NACC1: 13,116,468–13,141,147, forward strandNACC1STX10: 13,144,058–13,150,383, reverse strandSTX10IER2: 13,150,403–13,156,981, forward strandIER2Diagram of DHPS: 9 exons on the reverse strand of chromosome 19Exon 8: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 9: 12,675,717–12,675,933, 217 basesExon 8: 12,676,017–12,676,142, 126 basesExon 7: 12,677,108–12,677,211, 104 basesExon 6: 12,677,291–12,677,396, 106 basesExon 5: 12,679,457–12,679,543, 87 basesExon 4: 12,679,623–12,679,719, 97 basesExon 3: 12,679,801–12,679,922, 122 basesExon 2: 12,680,161–12,680,325, 165 basesExon 1: 12,681,560–12,681,880, 321 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 6.2 kb; 1,110 of those bases code for the protein.

How a genome test reads DHPS

4

positions in DHPS where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.2 kb of DHPS, introns included, not only the 1.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DHPS gene: deoxyhypusine synthase. Retrieved 16 October 2026, from https://dantelabs.com/genes/dhps

Vancouver

Dante Labs. DHPS gene: deoxyhypusine synthase [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dhps

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test