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Trait
High, narrow palate
The presence of a high and narrow palate.
Summary
- Also called
- Narrow, high-arched roof of mouth, Narrow, highly arched roof of mouth, Gothic palate, High narrow palate, High vaulted palate, Narrow and high arched palate, Narrow, high-arched palate, Narrow, highly arched palate
- Body system
- Abnormality of head or neck
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/high-narrow-palate.json"
page <- fromJSON(url)
page$trait$nameHigh, narrow palateHP:0002705
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Read the genes linked to High, narrow palate, and the rest of your genome, with one test.
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Get my Genome Test171 genes linked to High, narrow palate
Changes in these genes cause rare conditions in which High, narrow palate is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| COPB1coat protein complex I subunit beta 1 | Always | In 1 condition |
| CREBBPCREB binding lysine acetyltransferase | Always | In 1 condition |
| DHRS3dehydrogenase/reductase 3 | Always | In 1 condition |
| DSTdystonin | Always | In 1 condition |
| EP300EP300 lysine acetyltransferase | Always | In 1 condition |
| FBN1fibrillin 1 | Always | In 4 conditions |
| FGFR1fibroblast growth factor receptor 1 | Always | In 1 condition |
| INTUinturned planar cell polarity protein | Always | In 1 condition |
| JKAMPJNK1/MAPK8 associated membrane protein | Always | In 1 condition |
| KDM6Alysine demethylase 6A | Always | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Always | In 1 condition |
| MARS1methionyl-tRNA synthetase 1 | Always | In 1 condition |
| MYMXmyomixer, myoblast fusion factor | Always | In 1 condition |
| NDUFAF6NADH:ubiquinone oxidoreductase complex assembly factor 6 | Always | In 1 condition |
| NONOnon-POU domain containing octamer binding | Always | In 2 conditions |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| SCARF2scavenger receptor class F member 2 | Always | In 1 condition |
| SMSspermine synthase | Always | In 1 condition |
| SPOUT1SPOUT domain containing methyltransferase 1 | Always | In 1 condition |
| TBC1D32TBC1 domain family member 32 | Always | In 1 condition |
| ERMARDER membrane associated RNA degradation | Very often (80–99%) | In 1 condition |
| GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Very often (80–99%) | In 1 condition |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Very often (80–99%) | In 1 condition |
| NOTCH3notch receptor 3 | Very often (80–99%) | In 1 condition |
| RUNX2RUNX family transcription factor 2 | Very often (80–99%) | In 2 conditions |
| SKISKI proto-oncogene | Very often (80–99%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Very often (80–99%) | In 2 conditions |
| TAF1TATA-box binding protein associated factor 1 | Very often (80–99%) | In 1 condition |
| VPS13Bvacuolar protein sorting 13 homolog B | Very often (80–99%) | In 2 conditions |
| ABCD3ATP binding cassette subfamily D member 3 | Often (30–79%) | In 1 condition |
| AFF4ALF transcription elongation factor 4 | Often (30–79%) | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Often (30–79%) | In 1 condition |
| ASXL3ASXL transcriptional regulator 3 | Often (30–79%) | In 1 condition |
| ATP7AATPase copper transporting alpha | Often (30–79%) | In 1 condition |
| CCDC22CCC complex scaffolding subunit CCDC22 | Often (30–79%) | In 1 condition |
| CDC45cell division cycle 45 | Often (30–79%) | In 1 condition |
| CDC6cell division cycle 6 | Often (30–79%) | In 1 condition |
| CDK10cyclin dependent kinase 10 | Often (30–79%) | In 1 condition |
| CDT1chromatin licensing and DNA replication factor 1 | Often (30–79%) | In 1 condition |
| CHD6chromodomain helicase DNA binding protein 6 | Often (30–79%) | In 1 condition |
Show 131 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| DIS3L2DIS3 like 3'-5' exoribonuclease 2 | Often (30–79%) | In 1 condition |
| DPM1dolichyl-phosphate mannosyltransferase subunit 1, catalytic | Often (30–79%) | In 2 conditions |
| DPYSL5dihydropyrimidinase like 5 | Often (30–79%) | In 1 condition |
| DVL1dishevelled segment polarity protein 1 | Often (30–79%) | In 1 condition |
| DVL3dishevelled segment polarity protein 3 | Often (30–79%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Often (30–79%) | In 1 condition |
| FZD2frizzled class receptor 2 | Often (30–79%) | In 1 condition |
| GIPC1GIPC PDZ domain containing family member 1 | Often (30–79%) | In 1 condition |
| GMNNgeminin DNA replication inhibitor | Often (30–79%) | In 1 condition |
| GPC3glypican 3 | Often (30–79%) | In 1 condition |
| GPC4glypican 4 | Often (30–79%) | In 1 condition |
| HPGD15-hydroxyprostaglandin dehydrogenase | Often (30–79%) | In 1 condition |
| KCNK9potassium two pore domain channel subfamily K member 9 | Often (30–79%) | In 1 condition |
| LRP12LDL receptor related protein 12 | Often (30–79%) | In 1 condition |
| NOTCH2NLCnotch 2 N-terminal like C | Often (30–79%) | In 1 condition |
| NUTM2B-AS1NUTM2B antisense RNA 1 | Often (30–79%) | In 1 condition |
| ORC1origin recognition complex subunit 1 | Often (30–79%) | In 1 condition |
| ORC4origin recognition complex subunit 4 | Often (30–79%) | In 1 condition |
| ORC6origin recognition complex subunit 6 | Often (30–79%) | In 1 condition |
| PIGTphosphatidylinositol glycan anchor biosynthesis class T | Often (30–79%) | In 1 condition |
| RILPL1Rab interacting lysosomal protein like 1 | Often (30–79%) | In 1 condition |
| SLC25A12solute carrier family 25 member 12 | Often (30–79%) | In 1 condition |
| SLC6A17solute carrier family 6 member 17 | Often (30–79%) | In 1 condition |
| SLCO2A1solute carrier organic anion transporter family member 2A1 | Often (30–79%) | In 1 condition |
| SMG9SMG9 nonsense mediated mRNA decay factor | Often (30–79%) | In 1 condition |
| TAOK1TAO kinase 1 | Often (30–79%) | In 1 condition |
| TCTN3tectonic family member 3 | Often (30–79%) | In 1 condition |
| TGFB2transforming growth factor beta 2 | Often (30–79%) | In 2 conditions |
| UBE3Bubiquitin protein ligase E3B | Often (30–79%) | In 1 condition |
| VAC14VAC14 component of PIKFYVE complex | Often (30–79%) | In 1 condition |
| VPS35LVPS35 endosomal protein sorting factor like | Often (30–79%) | In 1 condition |
| WASHC5WASH complex subunit 5 | Often (30–79%) | In 1 condition |
| WNT5AWnt family member 5A | Often (30–79%) | In 1 condition |
| AARS1alanyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| ACTA1actin alpha 1, skeletal muscle | Sometimes (5–29%) | In 1 condition |
| ACTA2actin alpha 2, smooth muscle | Sometimes (5–29%) | In 1 condition |
| ADNPactivity dependent neuroprotector homeobox | Sometimes (5–29%) | In 1 condition |
| APCAPC regulator of Wnt signaling pathway | Sometimes (5–29%) | In 1 condition |
| BCRBCR activator of RhoGEF and GTPase | Sometimes (5–29%) | In 1 condition |
| BMPR1Abone morphogenetic protein receptor type 1A | Sometimes (5–29%) | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| COL11A1collagen type XI alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| COL12A1collagen type XII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| COL3A1collagen type III alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| CPT2carnitine palmitoyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| CRKLCRK like proto-oncogene, adaptor protein | Sometimes (5–29%) | In 1 condition |
| DBR1debranching RNA lariats 1 | Sometimes (5–29%) | In 1 condition |
| DDX59DEAD-box helicase 59 | Sometimes (5–29%) | In 1 condition |
| EFEMP2EGF-like fibulin extracellular matrix protein 2 | Sometimes (5–29%) | In 1 condition |
| ELNelastin | Sometimes (5–29%) | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Sometimes (5–29%) | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Sometimes (5–29%) | In 1 condition |
| FOXE3forkhead box E3 | Sometimes (5–29%) | In 1 condition |
| GRB10growth factor receptor bound protein 10 | Sometimes (5–29%) | In 1 condition |
| GTF2E2general transcription factor IIE subunit 2 | Sometimes (5–29%) | In 1 condition |
| GTF2H5general transcription factor IIH subunit 5 | Sometimes (5–29%) | In 1 condition |
| GTF3C3general transcription factor IIIC subunit 3 | Sometimes (5–29%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| HEY2hes related family bHLH transcription factor with YRPW motif 2 | Sometimes (5–29%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Sometimes (5–29%) | In 2 conditions |
| IPO8importin 8 | Sometimes (5–29%) | In 1 condition |
| KIF26Akinesin family member 26A | Sometimes (5–29%) | In 1 condition |
| KLHL41kelch like family member 41 | Sometimes (5–29%) | In 1 condition |
| LOXlysyl oxidase | Sometimes (5–29%) | In 1 condition |
| LRP4LDL receptor related protein 4 | Sometimes (5–29%) | In 1 condition |
| MAPK1mitogen-activated protein kinase 1 | Sometimes (5–29%) | In 1 condition |
| MAT2Amethionine adenosyltransferase 2A | Sometimes (5–29%) | In 1 condition |
| MED12Lmediator complex subunit 12L | Sometimes (5–29%) | In 1 condition |
| MED25mediator complex subunit 25 | Sometimes (5–29%) | In 1 condition |
| MEGF8multiple EGF like domains 8 | Sometimes (5–29%) | In 1 condition |
| MFAP5microfibril associated protein 5 | Sometimes (5–29%) | In 1 condition |
| MPLKIPM-phase specific PLK1 interacting protein | Sometimes (5–29%) | In 1 condition |
| MYH11myosin heavy chain 11 | Sometimes (5–29%) | In 1 condition |
| MYLKmyosin light chain kinase | Sometimes (5–29%) | In 1 condition |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Sometimes (5–29%) | In 2 conditions |
| NEBnebulin | Sometimes (5–29%) | In 1 condition |
| NHSNHS actin remodeling regulator | Sometimes (5–29%) | In 1 condition |
| PCDHGC4protocadherin gamma subfamily C, 4 | Sometimes (5–29%) | In 1 condition |
| PORcytochrome p450 oxidoreductase | Sometimes (5–29%) | In 1 condition |
| PRKG1protein kinase cGMP-dependent 1 | Sometimes (5–29%) | In 1 condition |
| PTDSS1phosphatidylserine synthase 1 | Sometimes (5–29%) | In 1 condition |
| PTENphosphatase and tensin homolog | Sometimes (5–29%) | In 1 condition |
| RNF113Aring finger protein 113A | Sometimes (5–29%) | In 1 condition |
| SLC25A24solute carrier family 25 member 24 | Sometimes (5–29%) | In 1 condition |
| SLC6A1solute carrier family 6 member 1 | Sometimes (5–29%) | In 1 condition |
| SLC6A11solute carrier family 6 member 11 | Sometimes (5–29%) | In 1 condition |
| SMAD2SMAD family member 2 | Sometimes (5–29%) | In 1 condition |
| SMAD3SMAD family member 3 | Sometimes (5–29%) | In 1 condition |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| SPRED2sprouty related EVH1 domain containing 2 | Sometimes (5–29%) | In 1 condition |
| TARS1threonyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| TBCKTBC1 domain containing kinase | Sometimes (5–29%) | In 1 condition |
| TGFB3transforming growth factor beta 3 | Sometimes (5–29%) | In 1 condition |
| TGFBR1transforming growth factor beta receptor 1 | Sometimes (5–29%) | In 1 condition |
| TGFBR2transforming growth factor beta receptor 2 | Sometimes (5–29%) | In 1 condition |
| THSD4thrombospondin type 1 domain containing 4 | Sometimes (5–29%) | In 1 condition |
| TPM3tropomyosin 3 | Sometimes (5–29%) | In 1 condition |
| UFC1ubiquitin-fold modifier conjugating enzyme 1 | Sometimes (5–29%) | In 1 condition |
| WNT7AWnt family member 7A | Sometimes (5–29%) | In 1 condition |
| FOXP2forkhead box P2 | Rarely (1–4%) | In 1 condition |
| PLOD1procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Not recorded | In 1 condition |
| ANTXR1ANTXR cell adhesion molecule 1 | Not recorded | In 1 condition |
| ARID2AT-rich interaction domain 2 | Not recorded | In 1 condition |
| ARL6ARF like GTPase 6 | Not recorded | In 1 condition |
| ATN1atrophin 1 | Not recorded | In 1 condition |
| BBS1Bardet-Biedl syndrome 1 | Not recorded | In 1 condition |
| BCORBCL6 corepressor | Not recorded | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Not recorded | In 1 condition |
| CCDC28Bcoiled-coil domain containing 28B | Not recorded | In 1 condition |
| CNTN1contactin 1 | Not recorded | In 1 condition |
| HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | Not recorded | In 1 condition |
| IFT122intraflagellar transport 122 | Not recorded | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Not recorded | In 1 condition |
| MCM3APminichromosome maintenance complex component 3 associated protein | Not recorded | In 1 condition |
| MUSKmuscle associated receptor tyrosine kinase | Not recorded | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Not recorded | In 1 condition |
| PCLOpiccolo presynaptic cytomatrix protein | Not recorded | In 1 condition |
| PEX1peroxisomal biogenesis factor 1 | Not recorded | In 1 condition |
| PEX5peroxisomal biogenesis factor 5 | Not recorded | In 1 condition |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Not recorded | In 1 condition |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Not recorded | In 1 condition |
| RECQL4RecQ like helicase 4 | Not recorded | In 1 condition |
| RETret proto-oncogene | Not recorded | In 1 condition |
| SIN3ASIN3 transcription regulator family member A | Not recorded | In 1 condition |
| SPRED1sprouty related EVH1 domain containing 1 | Not recorded | In 1 condition |
| TBX1T-box transcription factor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks