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Gene

INTU

inturned planar cell polarity protein

Summary

Cytogenetic location
4q28.1
Coordinates
Chromosome 4: 127,632,957–127,726,737 (GRCh38)
Exons
16 exons across 93.8 kb
Protein
942 amino acids
Also known as
KIAA1284, CPLANE4
Previous symbols
PDZK6, PDZD6
MANE Select transcript
ENST00000335251.11NM_015693.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads INTU yet. The test sequences your whole genome, so your data includes it all the same.

How INTU is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 4, with a bracket where INTU sits. INTU and 6 genes near it on chromosome 4, from 127,179,847 to 128,179,846.Chromosome 44q28.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.2127.2 Mb127.4 Mb127.6 Mb127.8 Mb128 MbINTU: 127,632,957–127,726,737, forward strandINTUSLC25A31: 127,730,400–127,774,292, forward strandSLC25A31HSPA4L: 127,781,821–127,840,733, forward strandHSPA4LPLK4: 127,880,890–127,899,224, forward strandPLK4MFSD8: 127,917,799–127,966,034, reverse strandMFSD8ABHD18: 127,965,252–128,039,953, forward strandABHD18LARP1B: 128,060,638–128,222,931, forward strandLARP1BDiagram of INTU: 16 exons on the forward strand of chromosome 4Exon 2: 2 known disease-causing sitesExon 4: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 1: 127,632,957–127,633,180, 224 basesExon 2: 127,643,521–127,644,056, 536 basesExon 3: 127,656,636–127,656,721, 86 basesExon 4: 127,663,381–127,663,584, 204 basesExon 5: 127,669,036–127,669,154, 119 basesExon 6: 127,674,124–127,674,213, 90 basesExon 7: 127,684,409–127,684,486, 78 basesExon 8: 127,687,678–127,687,867, 190 basesExon 9: 127,700,010–127,700,063, 54 basesExon 10: 127,704,228–127,704,290, 63 basesExon 11: 127,705,591–127,705,812, 222 basesExon 12: 127,706,487–127,706,969, 483 basesExon 13: 127,708,571–127,708,668, 98 basesExon 14: 127,710,913–127,711,102, 190 basesExon 15: 127,713,936–127,714,093, 158 basesExon 16: 127,716,325–127,726,737, 10,413 bases12468101214165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 13.2 kb of the gene's 93.8 kb; 2,829 of those bases code for the protein.

How a genome test reads INTU

7

positions in INTU where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 93.8 kb of INTU, introns included, not only the 13.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). INTU gene: inturned planar cell polarity protein. Retrieved 16 October 2026, from https://dantelabs.com/genes/intu

Vancouver

Dante Labs. INTU gene: inturned planar cell polarity protein [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/intu

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