Gene
WNT7A
Wnt family member 7A
- HGNC 12786↗(opens in a new tab)
- Ensembl gene ENSG00000154764↗(opens in a new tab)
- NCBI Gene 7476↗(opens in a new tab)
Summary
- Cytogenetic location
- 3p25.1
- Coordinates
- Chromosome 3: 13,816,258–13,880,071 (GRCh38)
- Exons
- 4 exons across 63.8 kb
- Protein
- 349 amino acids
- Also known as
- Wnt-7a
- MANE Select transcript
- ENST00000285018.5NM_004625.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads WNT7A yet. The test sequences your whole genome, so your data includes it all the same.
How WNT7A is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4 kb of the gene's 63.8 kb; 1,050 of those bases code for the protein.
How a genome test reads WNT7A
4
positions in WNT7A where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 63.8 kb of WNT7A, introns included, not only the 4 kb of exons.
Traits linked to WNT7A
The Human Phenotype Ontology lists these as features of the rare conditions WNT7A can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Absent/small extremities
- Abnormality of the shankbone
- Absence/underdevelopment of inner forearm bone
- Absent calf bone
- Absent fingers
- Absent/small calf bone
- Absent/small thighbone
- Aplasia of the ulna
Show 41 more traits
- Bowed thighbone
- Bowing of outer large bone of the forearm
- Bowing of the long bones
- Cleft hand
- Missing toes
- Short foot
- Smaller or shorter than typical limbs
- Underdeveloped outer large forearm bone
- Abnormal finger flexion crease
- Absent kneecap
- Absent/small ankle bone
- Absent/small fingers
- Absent/small little finger
- Absent/small long bone of foot
- Absent/small long bones of hand
- Absent/small toe bones
- Absent/small wrist bones
- Aplasia/Hypoplasia of the phalanges of the hand
- Club feet
- Dislocated hip since birth
- Elbow ankylosis
- Elbow flexion contracture
- Extra little finger
- Finger bends toward pinky
- Fused toes
- Fusion of upper and lower arm bones
- Phocomelia
- Split hand
- Finger syndactyly
- Hip dislocation
- Talipes
- Absent wrist bone
- Curvature of digit
- Front half of foot turns inward
- Knock knees
- More than five fingers or toes on hands or feet
- Oligodactyly
- Postaxial polydactyly
- Preaxial polydactyly
- Short fingers or toes
- Webbed fingers or toes
Abnormality of head or neck
- Broad neck
- Little lower jaw
- Long face
- Short neck
- Cleft palate
- Cranial defect
- High, narrow palate
- Short nose
Show 5 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). WNT7A gene: Wnt family member 7A. Retrieved 17 October 2026, from https://dantelabs.com/genes/wnt7a
Dante Labs. WNT7A gene: Wnt family member 7A [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/wnt7a
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