Gene
JKAMP
JNK1/MAPK8 associated membrane protein
- HGNC 20184↗(opens in a new tab)
- Ensembl gene ENSG00000050130↗(opens in a new tab)
- NCBI Gene 51528↗(opens in a new tab)
Summary
- Cytogenetic location
- 14q23.1
- Coordinates
- Chromosome 14: 59,484,517–59,505,410 (GRCh38)
- Exons
- 7 exons across 20.9 kb
- Protein
- 311 amino acids
- Also known as
- HSPC213, JAMP, HSPC327, CDA06
- Previous symbols
- C14orf100
- MANE Select transcript
- ENST00000616435.5NM_016475.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How JKAMP is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.3 kb of the gene's 20.9 kb; 936 of those bases code for the protein.
Traits linked to JKAMP
The Human Phenotype Ontology lists these as features of the rare conditions JKAMP can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal gait
- Absent speech development
- Aggressive behavior
- Astrocytosis
- Autism spectrum disorder
- Bilateral tonic-clonic seizure with generalized onset
- Delayed ability to stand
- Delayed ability to walk
Show 38 more traits
- Delayed speech and language development
- Difficulty falling asleep
- Difficulty sleeping
- EEG with focal sharp slow waves
- EEG with spike-wave complexes
- Encephalopathy
- Epilepsy
- Falls
- Febrile seizure (within the age range of 3 months to 6 years)
- Febrile status epilepticus
- Global developmental delay
- Happy demeanor
- Inability to coordinate movements when walking
- Intellectual disability
- Intellectual disability, severe
- IQ less than 20
- Jerking
- Loss of brain cells
- More active than typical
- Motor delay
- Myoclonic seizure
- Poor eye contact
- Profound global developmental delay
- Reduced cerebral white matter volume
- Repeated seizures without recovery between them
- Severe global developmental delay
- Stereotypical hand wringing
- Toe walking
- Unsteady walk
- Decrease in size of the outer layer of the brain due to loss of brain cells
- Degeneration of cerebrum
- Delayed CNS myelination
- Generalized brain degeneration
- Loss of developmental milestones
- Choroid plexus cyst
- CNS demyelination
- Diffuse cerebral atrophy
- Extra-axial cerebrospinal fluid accumulation
Abnormality of head or neck
- Abnormal facial shape
- Abnormally small head
- Big calvaria
- Broad nasal tip
- Bulbous nose
- Coarse facial features
- Decreased size of nasal tip
- Depressed nasal bridge
Show 25 more traits
- Development of small head that was not present at birth
- Downturned corners of mouth
- Downward slanting of the opening between the eyelids
- Eye folds
- Flat back of skull
- Full cheeks
- High, narrow palate
- Highly arched eyebrow
- Little lower jaw
- Long eyelashes
- Long philtrum
- Low frontal hairline
- Low hairline at back of neck
- Monobrow
- Narrow forehead
- Nasal tip, upturned
- Receding chin
- Round face
- Short nose
- Short philtrum
- Sloping forehead
- Smooth philtrum
- Thick eyebrow
- Wide nasal bridge
- Widely spaced teeth
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). JKAMP gene: JNK1/MAPK8 associated membrane protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/jkamp
Dante Labs. JKAMP gene: JNK1/MAPK8 associated membrane protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/jkamp
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