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Gene

DHRS3

dehydrogenase/reductase 3

Summary

Cytogenetic location
1p36.21
Coordinates
Chromosome 1: 12,567,910–12,618,210 (GRCh38)
Exons
6 exons across 50.3 kb
Protein
302 amino acids
Also known as
retSDR1, Rsdr1, SDR1, RDH17, SDR16C1, CNALPTC1
MANE Select transcript
ENST00000616661.5NM_004753.7
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads DHRS3 yet. The test sequences your whole genome, so your data includes it all the same.

How DHRS3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where DHRS3 sits. DHRS3 and 18 genes near it on chromosome 1, from 12,093,060 to 13,093,059.Chromosome 11p36.21p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4412.2 Mb12.4 Mb12.6 Mb12.8 Mb13 MbTNFRSF8: 12,063,079–12,144,221, forward strandTNFRSF8TNFRSF1B: 12,166,970–12,209,228, forward strandTNFRSF1BVPS13D: 12,230,007–12,512,047, forward strandVPS13DDHRS3: 12,567,910–12,618,210, reverse strandDHRS3AADACL4: 12,644,085–12,667,076, forward strandAADACL4AADACL3: 12,716,109–12,728,760, forward strandAADACL3CFAP107: 12,746,194–12,763,699, forward strandCFAP107PRAMEF12: 12,773,738–12,777,906, forward strandPRAMEF12PRAMEF1: 12,791,397–12,796,628, forward strandPRAMEF1PRAMEF11: 12,824,605–12,831,410, reverse strandPRAMEF11HNRNPCL1: 12,847,377–12,848,720, reverse strandHNRNPCL1PRAMEF2: 12,857,086–12,861,909, forward strandPRAMEF2PRAMEF4: 12,879,212–12,886,201, reverse strandPRAMEF4PRAMEF10: 12,892,250–12,898,270, reverse strandPRAMEF7: 12,916,610–12,920,751, forward strandPRAMEF7PRAMEF6: 12,938,472–12,947,580, reverse strandPRAMEF6PRAMEF27: 13,049,476–13,056,575, reverse strandPRAMEF27HNRNPCL3: 13,060,769–13,062,878, forward strandHNRNPCL3PRAMEF25: 13,068,677–13,077,884, forward strandPRAMEF25Diagram of DHRS3: 6 exons on the reverse strand of chromosome 1Exon 6: 12,567,910–12,568,424, 515 basesExon 5: 12,572,728–12,572,853, 126 basesExon 4: 12,578,718–12,578,956, 239 basesExon 3: 12,579,293–12,579,412, 120 basesExon 2: 12,580,523–12,580,666, 144 basesExon 1: 12,617,154–12,618,210, 1,057 bases64215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 50.3 kb; 909 of those bases code for the protein.

Traits linked to DHRS3

The Human Phenotype Ontology lists these as features of the rare conditions DHRS3 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). DHRS3 gene: dehydrogenase/reductase 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/dhrs3

Vancouver

Dante Labs. DHRS3 gene: dehydrogenase/reductase 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dhrs3

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