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Gene

ORC6

origin recognition complex subunit 6

Summary

Cytogenetic location
16q11.2
Coordinates
Chromosome 16: 46,689,659–46,698,394 (GRCh38)
Exons
7 exons across 8.7 kb
Protein
252 amino acids
Previous symbols
ORC6L
MANE Select transcript
ENST00000219097.7NM_014321.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ORC6 yet. The test sequences your whole genome, so your data includes it all the same.

How ORC6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 16, with a bracket where ORC6 sits. ORC6 and 8 genes near it on chromosome 16, from 46,194,027 to 47,194,026.Chromosome 1616q11.2p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.346.2 Mb46.4 Mb46.6 Mb46.8 Mb47 MbSHCBP1: 46,578,565–46,621,404, reverse strandSHCBP1VPS35: 46,656,132–46,689,518, reverse strandVPS35ORC6: 46,689,659–46,698,394, forward strandORC6MYLK3: 46,701,568–46,790,407, reverse strandMYLK3HDIP1: 46,796,603–46,831,476, reverse strandHDIP1GPT2: 46,882,857–46,931,299, forward strandGPT2DNAJA2: 46,955,362–46,973,709, reverse strandDNAJA2NETO2: 47,077,703–47,144,028, reverse strandNETO2ITFG1: 47,154,387–47,464,149, reverse strandITFG1Diagram of ORC6: 7 exons on the forward strand of chromosome 16Exon 1: 3 known disease-causing sitesExon 2: 1 known disease-causing siteExon 3: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 1: 46,689,659–46,689,770, 112 basesExon 2: 46,690,991–46,691,120, 130 basesExon 3: 46,692,382–46,692,545, 164 basesExon 4: 46,693,093–46,693,182, 90 basesExon 5: 46,695,562–46,695,674, 113 basesExon 6: 46,696,017–46,696,085, 69 basesExon 7: 46,697,458–46,698,394, 937 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 8.7 kb; 759 of those bases code for the protein.

How a genome test reads ORC6

8

positions in ORC6 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 8.7 kb of ORC6, introns included, not only the 1.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ORC6 gene: origin recognition complex subunit 6. Retrieved 16 October 2026, from https://dantelabs.com/genes/orc6

Vancouver

Dante Labs. ORC6 gene: origin recognition complex subunit 6 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/orc6

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