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Gene

TARS1

threonyl-tRNA synthetase 1

Summary

Cytogenetic location
5p13.3
Coordinates
Chromosome 5: 33,440,965–33,468,086 (GRCh38)
Exons
19 exons across 27.1 kb
Protein
723 amino acids
Previous symbols
TARS
MANE Select transcript
ENST00000265112.8NM_152295.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TARS1 yet. The test sequences your whole genome, so your data includes it all the same.

How TARS1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where TARS1 sits. TARS1 and 3 genes near it on chromosome 5, from 32,954,526 to 33,954,525.Chromosome 55p13.3p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.333 Mb33.2 Mb33.4 Mb33.6 Mb33.8 MbTARS1: 33,440,965–33,468,086, forward strandTARS1ADAMTS12: 33,523,535–33,892,113, reverse strandADAMTS12RXFP3: 33,936,386–33,938,918, forward strandRXFP3SLC45A2: 33,943,530–33,986,124, reverse strandSLC45A2Diagram of TARS1: 19 exons on the forward strand of chromosome 5Exon 16: 1 known disease-causing siteExon 1: 33,440,965–33,441,143, 179 basesExon 2: 33,445,324–33,445,404, 81 basesExon 3: 33,448,541–33,448,731, 191 basesExon 4: 33,453,289–33,453,412, 124 basesExon 5: 33,454,945–33,455,066, 122 basesExon 6: 33,455,587–33,455,704, 118 basesExon 7: 33,456,002–33,456,066, 65 basesExon 8: 33,456,149–33,456,227, 79 basesExon 9: 33,457,257–33,457,403, 147 basesExon 10: 33,458,566–33,458,664, 99 basesExon 11: 33,459,695–33,459,861, 167 basesExon 12: 33,460,902–33,461,064, 163 basesExon 13: 33,461,158–33,461,295, 138 basesExon 14: 33,461,667–33,461,744, 78 basesExon 15: 33,461,906–33,462,006, 101 basesExon 16: 33,462,099–33,462,203, 105 basesExon 17: 33,463,753–33,463,825, 73 basesExon 18: 33,466,871–33,466,985, 115 basesExon 19: 33,467,560–33,468,086, 527 bases151015195′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 27.1 kb; 2,172 of those bases code for the protein.

How a genome test reads TARS1

1

position in TARS1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 27.1 kb of TARS1, introns included, not only the 2.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TARS1 gene: threonyl-tRNA synthetase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/tars1

Vancouver

Dante Labs. TARS1 gene: threonyl-tRNA synthetase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tars1

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