Skip to content
Use your HSA or FSA funds

Gene

COPB1

coat protein complex I subunit beta 1

Summary

Cytogenetic location
11p15.2
Coordinates
Chromosome 11: 14,457,512–14,499,811 (GRCh38)
Exons
22 exons across 42.3 kb
Protein
953 amino acids
Previous symbols
COPB
MANE Select transcript
ENST00000439561.7NM_001144061.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads COPB1 yet. The test sequences your whole genome, so your data includes it all the same.

How COPB1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where COPB1 sits. COPB1 and 8 genes near it on chromosome 11, from 13,978,662 to 14,978,661.Chromosome 1111p15.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2514 Mb14.2 Mb14.4 Mb14.6 Mb14.8 MbSPON1: 13,962,372–14,268,133, forward strandSPON1RRAS2: 14,277,919–14,364,506, reverse strandRRAS2COPB1: 14,457,512–14,499,811, reverse strandCOPB1: 14,493,783–14,520,344, reverse strandPSMA1: 14,504,211–14,643,635, reverse strandPSMA1PDE3B: 14,643,663–14,874,657, forward strandPDE3BCYP2R1: 14,877,349–14,892,262, reverse strandCYP2R1CALCB: 14,904,997–15,083,701, forward strandCALCBCALCA: 14,966,622–14,972,357, reverse strandCALCADiagram of COPB1: 22 exons on the reverse strand of chromosome 11Exon 14: 1 known disease-causing siteExon 22: 14,457,512–14,457,883, 372 basesExon 21: 14,458,532–14,458,687, 156 basesExon 20: 14,460,208–14,460,297, 90 basesExon 19: 14,461,186–14,461,331, 146 basesExon 18: 14,464,911–14,465,030, 120 basesExon 17: 14,466,282–14,466,426, 145 basesExon 16: 14,468,681–14,468,860, 180 basesExon 15: 14,469,336–14,469,563, 228 basesExon 14: 14,474,495–14,474,615, 121 basesExon 13: 14,475,785–14,475,945, 161 basesExon 12: 14,476,919–14,477,015, 97 basesExon 11: 14,479,569–14,479,714, 146 basesExon 10: 14,480,759–14,480,905, 147 basesExon 9: 14,480,990–14,481,097, 108 basesExon 8: 14,483,032–14,483,151, 120 basesExon 7: 14,486,367–14,486,504, 138 basesExon 6: 14,488,492–14,488,584, 93 basesExon 5: 14,490,565–14,490,679, 115 basesExon 4: 14,493,642–14,493,811, 170 basesExon 3: 14,494,210–14,494,439, 230 basesExon 2: 14,498,838–14,498,985, 148 basesExon 1: 14,499,707–14,499,811, 105 bases22201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 42.3 kb; 2,862 of those bases code for the protein.

How a genome test reads COPB1

1

position in COPB1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 42.3 kb of COPB1, introns included, not only the 3.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). COPB1 gene: coat protein complex I subunit beta 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/copb1

Vancouver

Dante Labs. COPB1 gene: coat protein complex I subunit beta 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/copb1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test