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Gene

HEY2

hes related family bHLH transcription factor with YRPW motif 2

Summary

Cytogenetic location
6q22.31
Coordinates
Chromosome 6: 125,749,632–125,761,269 (GRCh38)
Exons
5 exons across 11.6 kb
Protein
337 amino acids
Also known as
bHLHb32, HERP1, HESR2
MANE Select transcript
ENST00000368364.4NM_012259.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads HEY2 yet. The test sequences your whole genome, so your data includes it all the same.

How HEY2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 6, with a bracket where HEY2 sits. HEY2 and 5 genes near it on chromosome 6, from 125,255,451 to 126,255,450.Chromosome 66q22.31p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q27125.4 Mb125.6 Mb125.8 Mb126 Mb126.2 MbTPD52L1: 125,119,049–125,264,407, forward strandTPD52L1HDDC2: 125,219,962–125,302,146, reverse strandHDDC2HEY2: 125,749,632–125,761,269, forward strandHEY2NCOA7: 125,780,943–125,932,034, forward strandNCOA7HINT3: 125,956,733–125,980,315, forward strandHINT3TRMT11: 125,986,423–126,203,817, forward strandTRMT11Diagram of HEY2: 5 exons on the forward strand of chromosome 6Exon 1: 125,749,632–125,749,859, 228 basesExon 2: 125,751,801–125,751,879, 79 basesExon 3: 125,752,007–125,752,090, 84 basesExon 4: 125,754,465–125,754,546, 82 basesExon 5: 125,759,117–125,761,269, 2,153 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 11.6 kb; 1,014 of those bases code for the protein.

Traits linked to HEY2

The Human Phenotype Ontology lists these as features of the rare conditions HEY2 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). HEY2 gene: hes related family bHLH transcription factor with YRPW motif 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/hey2

Vancouver

Dante Labs. HEY2 gene: hes related family bHLH transcription factor with YRPW motif 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hey2

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