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Gene

DPYSL5

dihydropyrimidinase like 5

Summary

Cytogenetic location
2p23.3
Coordinates
Chromosome 2: 26,848,132–26,950,351 (GRCh38)
Exons
13 exons across 102.2 kb
Protein
564 amino acids
Also known as
CRMP5, Ulip6, CRMP-5, CRAM, CV2
MANE Select transcript
ENST00000288699.11NM_020134.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads DPYSL5 yet. The test sequences your whole genome, so your data includes it all the same.

How DPYSL5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where DPYSL5 sits. DPYSL5 and 31 genes near it on chromosome 2, from 26,399,242 to 27,399,241.Chromosome 22p23.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.326.4 Mb26.6 Mb26.8 Mb27 Mb27.2 MbDRC1: 26,401,908–26,456,717, forward strandDRC1OTOF: 26,457,203–26,558,756, reverse strandOTOFCIMIP2C: 26,562,542–26,581,178, forward strandCIMIP2CCIB4: 26,579,428–26,641,366, reverse strandCIB4KCNK3: 26,692,713–26,733,420, forward strandKCNK3SLC35F6: 26,764,240–26,781,231, forward strandSLC35F6CENPA: 26,764,289–26,801,067, forward strandCENPADPYSL5: 26,848,132–26,950,351, forward strandDPYSL5MAPRE3: 26,970,400–27,027,219, forward strandMAPRE3TMEM214: 27,032,910–27,041,697, forward strandTMEM214AGBL5: 27,042,364–27,070,622, forward strandAGBL5OST4: 27,058,735–27,073,830, reverse strandOST4EMILIN1: 27,078,044–27,086,408, forward strandEMILIN1KHK: 27,086,723–27,100,777, forward strandKHKCGREF1: 27,098,853–27,119,139, reverse strandABHD1: 27,123,789–27,130,812, forward strandABHD1PREB: 27,129,153–27,134,689, reverse strandPRR30: 27,136,848–27,139,410, reverse strandPRR30TCF23: 27,148,999–27,156,974, forward strandTCF23SLC5A6: 27,199,587–27,212,958, reverse strandSLC5A6ATRAID: 27,212,012–27,217,178, forward strandATRAIDCAD: 27,217,345–27,245,683, forward strandCADSLC30A3: 27,253,509–27,275,817, reverse strandSLC30A3DNAJC5G: 27,275,430–27,281,499, forward strandDNAJC5GTRIM54: 27,282,366–27,309,400, forward strandTRIM54UCN: 27,307,400–27,308,445, reverse strandUCNMPV17: 27,309,486–27,325,680, reverse strandGTF3C2: 27,324,198–27,357,566, reverse strandGTF3C2EIF2B4: 27,363,420–27,370,466, reverse strandEIF2B4SNX17: 27,370,496–27,377,535, forward strandSNX17ZNF513: 27,377,235–27,380,790, reverse strandZNF513PPM1G: 27,381,194–27,409,674, reverse strandDiagram of DPYSL5: 13 exons on the forward strand of chromosome 2Exon 2: 1 known disease-causing siteExon 1: 26,848,132–26,848,254, 123 basesExon 2: 26,898,496–26,898,760, 265 basesExon 3: 26,924,887–26,925,045, 159 basesExon 4: 26,927,253–26,927,432, 180 basesExon 5: 26,928,255–26,928,323, 69 basesExon 6: 26,931,640–26,931,684, 45 basesExon 7: 26,933,258–26,933,333, 76 basesExon 8: 26,934,578–26,934,734, 157 basesExon 9: 26,940,031–26,940,172, 142 basesExon 10: 26,941,950–26,942,092, 143 basesExon 11: 26,942,543–26,942,750, 208 basesExon 12: 26,944,656–26,944,824, 169 basesExon 13: 26,946,910–26,950,351, 3,442 bases124681012135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.2 kb of the gene's 102.2 kb; 1,695 of those bases code for the protein.

How a genome test reads DPYSL5

1

position in DPYSL5 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 102.2 kb of DPYSL5, introns included, not only the 5.2 kb of exons.

Traits linked to DPYSL5

The Human Phenotype Ontology lists these as features of the rare conditions DPYSL5 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DPYSL5 gene: dihydropyrimidinase like 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/dpysl5

Vancouver

Dante Labs. DPYSL5 gene: dihydropyrimidinase like 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dpysl5

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