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Gene

CRKL

CRK like proto-oncogene, adaptor protein

Summary

Cytogenetic location
22q11.21
Coordinates
Chromosome 22: 20,917,407–20,953,747 (GRCh38)
Exons
3 exons across 36.3 kb
Protein
303 amino acids
MANE Select transcript
ENST00000354336.8NM_005207.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CRKL yet. The test sequences your whole genome, so your data includes it all the same.

How CRKL is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where CRKL sits. CRKL and 18 genes near it on chromosome 22, from 20,435,577 to 21,435,576.Chromosome 2222q11.21p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3320.6 Mb20.8 Mb21 Mb21.2 Mb21.4 MbSCARF2: 20,424,584–20,438,332, reverse strandSCARF2: 20,429,241–20,446,620, reverse strandKLHL22: 20,441,519–20,496,893, reverse strandKLHL22MED15: 20,495,913–20,587,632, forward strandMED15PI4KA: 20,707,691–20,859,417, reverse strandPI4KASERPIND1: 20,774,092–20,787,721, forward strandSERPIND1SNAP29: 20,858,537–20,891,218, forward strandSNAP29CRKL: 20,917,407–20,953,747, forward strandCRKLAIFM3: 20,965,108–20,981,364, forward strandAIFM3LZTR1: 20,981,979–20,999,037, forward strandLZTR1THAP7: 20,999,104–21,002,196, reverse strandTHAP7LRRC74BNL: 21,007,199–21,014,301, reverse strandLRRC74BNL: 21,008,247–21,032,572, reverse strandP2RX6: 21,009,808–21,028,013, forward strandSLC7A4: 21,028,715–21,032,933, reverse strandLRRC74B: 21,045,941–21,064,168, forward strandFAM246A: 21,360,601–21,361,299, reverse strandFAM246ARIMBP3B: 21,383,751–21,389,478, forward strandRIMBP3BHIC2: 21,416,504–21,451,463, forward strandHIC2Diagram of CRKL: 3 exons on the forward strand of chromosome 22Exon 1: 20,917,407–20,918,245, 839 basesExon 2: 20,933,779–20,934,244, 466 basesExon 3: 20,949,711–20,953,747, 4,037 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.3 kb of the gene's 36.3 kb; 912 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). CRKL gene: CRK like proto-oncogene, adaptor protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/crkl

Vancouver

Dante Labs. CRKL gene: CRK like proto-oncogene, adaptor protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/crkl

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