유전자
LRRC7
leucine rich repeat containing 7
요약
- 세포유전학적 위치
- 1p31.1
- 좌표
- 염색체 1: 69,567,922–70,144,364 (GRCh38)
- 엑손
- 엑손 27개, 576.4 kb에 걸쳐
- 단백질
- 아미노산 1,575개
- 다른 이름
- KIAA1365, densin-180
- MANE Select 전사체
- ENST00000651989.2NM_001370785.2
- 유전자좌 유형
- gene with protein product
- Very high
- Confident
- Low
- Very low
기준 게놈GRCh38hg38
유전자 및 변이 페이지의 위치 정보는 이 브라우저에서 선택한 설정을 따릅니다.
이 유전자와 관련된 큐레이션 보고서
No Genome Test report reads LRRC7 yet. The test sequences your whole genome, so your data includes it all the same.
LRRC7의 구조
- 코딩 서열
- 비번역 영역
- 인트론
- 전사 방향
- 짧은 리드가 판독하기 어려운 구간
v1.5 릴리스 기준, 이 유전자의 MANE Select 전사체 엑손이며 NCBI와 EMBL-EBI 자료를 바탕으로 하고 GRCh38 참조 게놈에 기반합니다.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
유전자 전체 576.4 kb 중 엑손이 27.9 kb를 차지하며, 이 중 4,728개의 염기가 단백질을 암호화합니다.
Traits linked to LRRC7
The Human Phenotype Ontology lists these as features of the rare conditions LRRC7 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Anxiety
- Ataxia
- Attention deficit
- Autism spectrum disorder
- Behavioral abnormality
- Brief seizures with staring spells
- Can't control feelings
- Cerebellar vermis atrophy
Show 64 more traits
- Cerebral palsy
- Chiari type I malformation
- Clumsiness
- Complex febrile seizure
- Decreased reflex response
- Delayed ability to sit
- Delayed fine motor development
- Delayed motor skills
- Depression
- Difficulty articulating speech
- Difficulty falling asleep
- Dysgraphia
- Dystonia
- EEG abnormality
- Febrile seizure (within the age range of 3 months to 6 years)
- Fluid-filled cyst in spinal cord
- Frequent temper tantrums
- Global developmental delay
- Grammar-specific speech disorder
- Hallucinations
- Hallucinations of sound
- Hand tremor
- Headache
- Impulsivity
- Inability to coordinate movements when walking
- Inability to speak
- Inability to walk
- Incoordination
- Increased appetite
- Intellectual disability
- Intellectual disability, mild
- Intellectual disability, severe
- IQ between 34 and 49
- Irritability
- Low frustration tolerance
- Migraine
- Mild global developmental delay
- Moderate global developmental delay
- Moderate receptive language delay
- Pain insensitivity
- Pauses in breathing while sleeping
- Psychosis
- Reading disability
- Reduced impulse control
- Resting tremor
- Restlessness
- Selective mutism
- Self-injurious behavior
- Severe global developmental delay
- Short attention span
- Short corpus callosum
- Slow movements
- Thin corpus callosum
- Typical absence seizure
- Underdevelopment of part of brain called corpus callosum
- Unsteady walk
- Visual hallucinations
- Aggressive behavior
- Autism
- Delayed speech and language development
- Delayed ability to walk
- Epilepsy
- Difficulty sleeping
- Interictal epileptiform activity
Abnormality of the musculoskeletal system
- Appendicular hypotonia
- Basal ganglia calcification
- Cogwheel rigidity
- Double-Jointed
- Generalized decreased muscle tone
- Kyphoscoliosis
- Low muscle tone, in neonatal onset
- Muscle weakness
Show 4 more traits
외부 링크
단백질
이 정보의 출처
- HGNC: 유전자의 기호, 명칭, 다른 기호 및 위치입니다.
- NCBI와 EMBL-EBI의 MANE Select v1.5: 전사체, 엑손 및 코딩 서열입니다.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). LRRC7 gene: leucine rich repeat containing 7. Retrieved 2026년 10월 16일, from https://dantelabs.com/ko/genes/lrrc7
Dante Labs. LRRC7 gene: leucine rich repeat containing 7 [Internet]. [cited 2026년 10월 16일]. Available from: https://dantelabs.com/ko/genes/lrrc7
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