Trait
Thick eyebrow
Increased density/number and/or increased diameter of eyebrow hairs.
Summary
- Also called
- Bushy eyebrows, Dense eyebrow, Heavy eyebrows, Prominent eyebrows, Thick eyebrows, Hypertrichosis of the eyebrow
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test170 genes linked to Thick eyebrow
Changes in these genes cause rare conditions in which Thick eyebrow is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACER3alkaline ceramidase 3 | Always | In 1 condition |
| AFF4ALF transcription elongation factor 4 | Always | In 2 conditions |
| CDH11cadherin 11 | Always | In 2 conditions |
| CHASERRCHD2 adjacent suppressive regulatory RNA | Always | In 1 condition |
| CWF19L1CWF19 like cell cycle control factor 1 | Always | In 1 condition |
| DDX59DEAD-box helicase 59 | Always | In 1 condition |
| DENND5ADENN domain containing 5A | Always | In 1 condition |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Always | In 1 condition |
| FLNAfilamin A | Always | In 1 condition |
| JKAMPJNK1/MAPK8 associated membrane protein | Always | In 1 condition |
| KCNK4potassium two pore domain channel subfamily K member 4 | Always | In 1 condition |
| KNL1kinetochore scaffold 1 | Always | In 1 condition |
| LAS1LLAS1 like ribosome biogenesis factor | Always | In 2 conditions |
| MN1MN1 proto-oncogene, transcriptional regulator | Always | In 1 condition |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Always | In 1 condition |
| NAV3neuron navigator 3 | Always | In 1 condition |
| NIPBLNIPBL cohesin loading factor | Always | In 2 conditions |
| NOTCH2notch receptor 2 | Always | In 2 conditions |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Always | In 1 condition |
| PDCD6IPprogrammed cell death 6 interacting protein | Always | In 1 condition |
| POLR1ARNA polymerase I subunit A | Always | In 1 condition |
| PRKG2protein kinase cGMP-dependent 2 | Always | In 1 condition |
| PSMC1proteasome 26S subunit, ATPase 1 | Always | In 1 condition |
| SLC35A2solute carrier family 35 member A2 | Always | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Always | In 2 conditions |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| TASP1taspase 1 | Always | In 1 condition |
| TBL1XR1TBL1X/Y related 1 | Always | In 1 condition |
| TMCO1transmembrane and coiled-coil domains 1 | Always | In 2 conditions |
| VPS13Bvacuolar protein sorting 13 homolog B | Always | In 2 conditions |
| ABCC9ATP binding cassette subfamily C member 9 | Very often (80–99%) | In 1 condition |
| ARID1AAT-rich interaction domain 1A | Very often (80–99%) | In 2 conditions |
| ARID1BAT-rich interaction domain 1B | Very often (80–99%) | In 2 conditions |
| ARID2AT-rich interaction domain 2 | Very often (80–99%) | In 2 conditions |
| BRD4bromodomain containing 4 | Very often (80–99%) | In 1 condition |
| CCDC8coiled-coil domain containing 8 subunit of 3M complex | Very often (80–99%) | In 1 condition |
| CUL7cullin 7 | Very often (80–99%) | In 2 conditions |
| DPF2double PHD fingers 2 | Very often (80–99%) | In 2 conditions |
| HDAC8histone deacetylase 8 | Very often (80–99%) | In 2 conditions |
| IARS2isoleucyl-tRNA synthetase 2, mitochondrial | Very often (80–99%) | In 2 conditions |
Show 130 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| IDUAalpha-L-iduronidase | Very often (80–99%) | In 1 condition |
| KCNJ8potassium inwardly rectifying channel subfamily J member 8 | Very often (80–99%) | In 1 condition |
| KMT2Alysine methyltransferase 2A | Very often (80–99%) | In 2 conditions |
| MAU2MAU2 sister chromatid cohesion factor | Very often (80–99%) | In 2 conditions |
| OBSL1obscurin like cytoskeletal adaptor 1 | Very often (80–99%) | In 1 condition |
| PAX3paired box 3 | Very often (80–99%) | In 3 conditions |
| RAD21RAD21 cohesin complex component | Very often (80–99%) | In 3 conditions |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 1 condition |
| SLC9A6solute carrier family 9 member A6 | Very often (80–99%) | In 2 conditions |
| SMARCA4SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 | Very often (80–99%) | In 2 conditions |
| SMARCC2SWI/SNF related BAF chromatin remodeling complex subunit C2 | Very often (80–99%) | In 2 conditions |
| SMARCD1SWI/SNF related BAF chromatin remodeling complex subunit D1 | Very often (80–99%) | In 1 condition |
| SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1 | Very often (80–99%) | In 2 conditions |
| SMC1Astructural maintenance of chromosomes 1A | Very often (80–99%) | In 2 conditions |
| SMC3structural maintenance of chromosomes 3 | Very often (80–99%) | In 2 conditions |
| SOX11SRY-box transcription factor 11 | Very often (80–99%) | In 1 condition |
| SOX4SRY-box transcription factor 4 | Very often (80–99%) | In 1 condition |
| SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1 like | Very often (80–99%) | In 1 condition |
| TP63tumor protein p63 | Very often (80–99%) | In 1 condition |
| ANKRD11ankyrin repeat domain 11 | Often (30–79%) | In 2 conditions |
| ASCC3activating signal cointegrator 1 complex subunit 3 | Often (30–79%) | In 1 condition |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Often (30–79%) | In 2 conditions |
| AUTS2activator of transcription and developmental regulator AUTS2 | Often (30–79%) | In 1 condition |
| BCAS3BCAS3 microtubule associated cell migration factor | Often (30–79%) | In 1 condition |
| BORCS8BLOC-1 related complex subunit 8 | Often (30–79%) | In 1 condition |
| BPTFbromodomain PHD finger transcription factor | Often (30–79%) | In 1 condition |
| CACHD1cache domain containing 1 | Often (30–79%) | In 1 condition |
| CHD1chromodomain helicase DNA binding protein 1 | Often (30–79%) | In 1 condition |
| CNOT2CCR4-NOT transcription complex subunit 2 | Often (30–79%) | In 1 condition |
| CPLX1complexin 1 | Often (30–79%) | In 1 condition |
| CTCFCCCTC-binding factor | Often (30–79%) | In 2 conditions |
| DOCK7dedicator of cytokinesis 7 | Often (30–79%) | In 2 conditions |
| DYMdymeclin | Often (30–79%) | In 1 condition |
| EP300EP300 lysine acetyltransferase | Often (30–79%) | In 2 conditions |
| EXT1exostosin glycosyltransferase 1 | Often (30–79%) | In 1 condition |
| FHL1four and a half LIM domains 1 | Often (30–79%) | In 1 condition |
| FREM1FRAS1 related extracellular matrix 1 | Often (30–79%) | In 1 condition |
| FRMD4AFERM domain containing 4A | Often (30–79%) | In 2 conditions |
| GNSglucosamine (N-acetyl)-6-sulfatase | Often (30–79%) | In 1 condition |
| GON4Lgon-4 like | Often (30–79%) | In 1 condition |
| GPRASP2G protein-coupled receptor associated sorting protein 2 | Often (30–79%) | In 1 condition |
| GUSBglucuronidase beta | Often (30–79%) | In 1 condition |
| KCNH1potassium voltage-gated channel subfamily H member 1 | Often (30–79%) | In 3 conditions |
| KCNN3potassium calcium-activated channel subfamily N member 3 | Often (30–79%) | In 2 conditions |
| MTHFSmethenyltetrahydrofolate synthetase | Often (30–79%) | In 1 condition |
| NBASNBAS subunit of NRZ tethering complex | Often (30–79%) | In 1 condition |
| PHF6PHD finger protein 6 | Often (30–79%) | In 1 condition |
| PPP1R21protein phosphatase 1 regulatory subunit 21 | Often (30–79%) | In 1 condition |
| PRR12proline rich 12 | Often (30–79%) | In 1 condition |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Often (30–79%) | In 1 condition |
| RALGAPA1Ral GTPase activating protein catalytic subunit alpha 1 | Often (30–79%) | In 1 condition |
| RPS23ribosomal protein S23 | Often (30–79%) | In 1 condition |
| RUSC2RUN and SH3 domain containing 2 | Often (30–79%) | In 1 condition |
| SETD1BSET domain containing 1B, histone lysine methyltransferase | Often (30–79%) | In 1 condition |
| SHANK3SH3 and multiple ankyrin repeat domains 3 | Often (30–79%) | In 1 condition |
| SLC6A17solute carrier family 6 member 17 | Often (30–79%) | In 2 conditions |
| SUMF1sulfatase modifying factor 1 | Often (30–79%) | In 1 condition |
| TAF6TATA-box binding protein associated factor 6 | Often (30–79%) | In 1 condition |
| TRPS1transcriptional repressor GATA binding 1 | Often (30–79%) | In 1 condition |
| TUBGCP2tubulin gamma complex component 2 | Often (30–79%) | In 1 condition |
| ABCA5ATP binding cassette subfamily A member 5 | Sometimes (5–29%) | In 1 condition |
| ASXL3ASXL transcriptional regulator 3 | Sometimes (5–29%) | In 1 condition |
| BICRABRD4 interacting chromatin remodeling complex associated protein | Sometimes (5–29%) | In 1 condition |
| CDK13cyclin dependent kinase 13 | Sometimes (5–29%) | In 1 condition |
| CHMP1Acharged multivesicular body protein 1A | Sometimes (5–29%) | In 1 condition |
| CLCN3Cl-/H+ antiporter 3 | Sometimes (5–29%) | In 1 condition |
| COL1A2collagen type I alpha 2 chain | Sometimes (5–29%) | In 1 condition |
| CREBBPCREB binding lysine acetyltransferase | Sometimes (5–29%) | In 2 conditions |
| DDB1damage specific DNA binding protein 1 | Sometimes (5–29%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Sometimes (5–29%) | In 2 conditions |
| EBF3EBF transcription factor 3 | Sometimes (5–29%) | In 1 condition |
| ERLIN2ER lipid raft associated 2 | Sometimes (5–29%) | In 2 conditions |
| FBXL4F-box and leucine rich repeat protein 4 | Sometimes (5–29%) | In 1 condition |
| FBXO31F-box protein 31 | Sometimes (5–29%) | In 1 condition |
| FOXL2forkhead box L2 | Sometimes (5–29%) | In 1 condition |
| GNB2G protein subunit beta 2 | Sometimes (5–29%) | In 1 condition |
| GTF3C3general transcription factor IIIC subunit 3 | Sometimes (5–29%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| HIVEP2HIVEP zinc finger 2 | Sometimes (5–29%) | In 1 condition |
| HMGA2high mobility group AT-hook 2 | Sometimes (5–29%) | In 1 condition |
| IGF1Rinsulin like growth factor 1 receptor | Sometimes (5–29%) | In 1 condition |
| JARID2jumonji and AT-rich interaction domain containing 2 | Sometimes (5–29%) | In 1 condition |
| KDM5Clysine demethylase 5C | Sometimes (5–29%) | In 1 condition |
| LEMD3LEM domain containing 3 | Sometimes (5–29%) | In 1 condition |
| MEF2Cmyocyte enhancer factor 2C | Sometimes (5–29%) | In 1 condition |
| NOTCH3notch receptor 3 | Sometimes (5–29%) | In 1 condition |
| NRCAMneuronal cell adhesion molecule | Sometimes (5–29%) | In 1 condition |
| PUF60poly(U) binding splicing factor 60 | Sometimes (5–29%) | In 1 condition |
| RBM10RNA binding motif protein 10 | Sometimes (5–29%) | In 1 condition |
| RHOBTB2Rho related BTB domain containing 2 | Sometimes (5–29%) | In 1 condition |
| RNU2-2RNA, U2 small nuclear 2 | Sometimes (5–29%) | In 1 condition |
| SATB1SATB homeobox 1 | Sometimes (5–29%) | In 1 condition |
| SEPHS1selenophosphate synthetase 1 | Sometimes (5–29%) | In 1 condition |
| SIM1SIM bHLH transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Sometimes (5–29%) | In 1 condition |
| SOX6SRY-box transcription factor 6 | Sometimes (5–29%) | In 1 condition |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| TAF1TATA-box binding protein associated factor 1 | Sometimes (5–29%) | In 1 condition |
| TBCKTBC1 domain containing kinase | Sometimes (5–29%) | In 1 condition |
| TRIOtrio Rho guanine nucleotide exchange factor | Sometimes (5–29%) | In 1 condition |
| UBR7ubiquitin protein ligase E3 component n-recognin 7 | Sometimes (5–29%) | In 1 condition |
| WACWW domain containing adaptor with coiled-coil | Sometimes (5–29%) | In 2 conditions |
| WDR83OSWD repeat domain 83 opposite strand | Sometimes (5–29%) | In 1 condition |
| WNT4Wnt family member 4 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| ZSWIM6zinc finger SWIM-type containing 6 | Sometimes (5–29%) | In 1 condition |
| PTBP1polypyrimidine tract binding protein 1 | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
| AIFM1apoptosis inducing factor mitochondria associated 1 | Not recorded | In 1 condition |
| B3GAT3beta-1,3-glucuronyltransferase 3 | Not recorded | In 1 condition |
| BCORBCL6 corepressor | Not recorded | In 1 condition |
| CDONcell adhesion associated, oncogene regulated | Not recorded | In 1 condition |
| CHST3carbohydrate sulfotransferase 3 | Not recorded | In 1 condition |
| FUCA1alpha-L-fucosidase 1 | Not recorded | In 1 condition |
| HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | Not recorded | In 1 condition |
| KIFBPkinesin family binding protein | Not recorded | In 1 condition |
| KMT2Clysine methyltransferase 2C | Not recorded | In 1 condition |
| MAGEL2MAGE family member L2 | Not recorded | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Not recorded | In 1 condition |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Not recorded | In 1 condition |
| MBD5methyl-CpG binding domain protein 5 | Not recorded | In 1 condition |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Not recorded | In 1 condition |
| NFIXnuclear factor I X | Not recorded | In 1 condition |
| NSUN2NOP2/Sun RNA methyltransferase 2 | Not recorded | In 1 condition |
| PHIPPHIP subunit of CUL4-Ring ligase complex | Not recorded | In 1 condition |
| RETret proto-oncogene | Not recorded | In 1 condition |
| RNF125ring finger protein 125 | Not recorded | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Not recorded | In 1 condition |
| SMAD4SMAD family member 4 | Not recorded | In 1 condition |
| TFAP2Btranscription factor AP-2 beta | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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