Skip to content
Use your HSA or FSA funds

Gene

PSMD12

proteasome 26S subunit, non-ATPase 12

Summary

Cytogenetic location
17q24.2
Coordinates
Chromosome 17: 67,337,916–67,366,577 (GRCh38)
Exons
11 exons across 28.7 kb
Protein
456 amino acids
Also known as
p55, Rpn5
MANE Select transcript
ENST00000356126.8NM_002816.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PSMD12 yet. The test sequences your whole genome, so your data includes it all the same.

How PSMD12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where PSMD12 sits. PSMD12 and 7 genes near it on chromosome 17, from 66,852,247 to 67,852,246.Chromosome 1717q24.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.367 Mb67.2 Mb67.4 Mb67.6 Mb67.8 MbCACNG5: 66,835,117–66,894,751, forward strandCACNG5CACNG4: 66,964,494–67,035,678, forward strandCACNG4CACNG1: 67,044,531–67,058,016, forward strandCACNG1HELZ: 67,070,444–67,245,989, reverse strandHELZPSMD12: 67,337,916–67,366,577, reverse strandPSMD12PITPNC1: 67,377,258–67,697,256, forward strandPITPNC1NOL11: 67,717,810–67,744,531, forward strandNOL11BPTF: 67,825,488–67,984,378, forward strandBPTFDiagram of PSMD12: 11 exons on the reverse strand of chromosome 17Exon 9: 3 known disease-causing sitesExon 8: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 4: 3 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 11: 67,337,916–67,341,052, 3,137 basesExon 10: 67,342,186–67,342,263, 78 basesExon 9: 67,344,606–67,344,780, 175 basesExon 8: 67,345,745–67,345,857, 113 basesExon 7: 67,347,116–67,347,250, 135 basesExon 6: 67,347,336–67,347,485, 150 basesExon 5: 67,348,550–67,348,654, 105 basesExon 4: 67,350,229–67,350,336, 108 basesExon 3: 67,357,303–67,357,431, 129 basesExon 2: 67,357,519–67,357,578, 60 basesExon 1: 67,366,412–67,366,577, 166 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.4 kb of the gene's 28.7 kb; 1,371 of those bases code for the protein.

How a genome test reads PSMD12

14

positions in PSMD12 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 28.7 kb of PSMD12, introns included, not only the 4.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PSMD12 gene: proteasome 26S subunit, non-ATPase 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/psmd12

Vancouver

Dante Labs. PSMD12 gene: proteasome 26S subunit, non-ATPase 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/psmd12

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test