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Gene

DDB1

damage specific DNA binding protein 1

Summary

Cytogenetic location
11q12.2
Coordinates
Chromosome 11: 61,299,451–61,333,105 (GRCh38)
Exons
27 exons across 33.7 kb
Protein
1,140 amino acids
MANE Select transcript
ENST00000301764.12NM_001923.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DDB1 yet. The test sequences your whole genome, so your data includes it all the same.

How DDB1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where DDB1 sits. DDB1 and 30 genes near it on chromosome 11, from 60,816,278 to 61,816,277.Chromosome 1111q12.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2561 Mb61.2 Mb61.4 Mb61.6 Mb61.8 MbCCDC86: 60,841,981–60,851,095, forward strandCCDC86PTGDR2: 60,850,933–60,855,987, reverse strandPTGDR2ZP1: 60,867,542–60,875,693, forward strandZP1PRPF19: 60,890,547–60,906,607, reverse strandPRPF19TMEM109: 60,912,521–60,923,443, forward strandTMEM109TMEM132A: 60,924,453–60,937,159, forward strandTMEM132ASLC15A3: 60,937,060–60,952,653, reverse strandSLC15A3CD6: 60,971,651–61,020,377, forward strandCD6CD5: 61,102,466–61,127,952, forward strandCD5VPS37C: 61,111,002–61,167,355, reverse strandVPS37CPGA3: 61,203,307–61,213,098, forward strandPGA3PGA4: 61,222,347–61,231,694, forward strandPGA4PGA5: 61,241,175–61,251,444, forward strandPGA5VWCE: 61,255,672–61,295,553, reverse strandVWCEDDB1: 61,299,451–61,333,105, reverse strandDDB1TKFC: 61,333,205–61,354,339, forward strandTKFCCYB561A3: 61,348,453–61,362,343, reverse strandCYB561A3TMEM138: 61,361,964–61,377,890, forward strandTMEM138TMEM216: 61,392,393–61,400,408, forward strandTMEM216CPSF7: 61,402,641–61,430,105, reverse strandCPSF7: 61,429,220–61,485,822, forward strandSDHAF2: 61,430,032–61,473,614, forward strandSDHAF2SAXO4: 61,481,120–61,490,931, forward strandSAXO4LRRC10B: 61,508,749–61,511,018, forward strandLRRC10BSYT7: 61,513,714–61,581,201, reverse strandSYT7DAGLA: 61,680,151–61,747,003, forward strandDAGLAMYRF: 61,752,593–61,788,518, forward strandMYRFTMEM258: 61,768,455–61,792,802, reverse strandTMEM258FEN1: 61,792,725–61,797,238, forward strandFEN1FADS2: 61,792,980–61,867,354, forward strandFADS1: 61,799,624–61,829,318, reverse strandFADS1Diagram of DDB1: 27 exons on the reverse strand of chromosome 11Exon 19: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 27: 61,299,451–61,300,219, 769 basesExon 26: 61,300,809–61,300,932, 124 basesExon 25: 61,302,257–61,302,359, 103 basesExon 24: 61,302,582–61,302,751, 170 basesExon 23: 61,303,046–61,303,155, 110 basesExon 22: 61,303,865–61,304,035, 171 basesExon 21: 61,308,983–61,309,077, 95 basesExon 20: 61,309,796–61,309,960, 165 basesExon 19: 61,310,295–61,310,418, 124 basesExon 18: 61,311,784–61,311,895, 112 basesExon 17: 61,311,989–61,312,084, 96 basesExon 16: 61,313,499–61,313,706, 208 basesExon 15: 61,313,862–61,313,969, 108 basesExon 14: 61,314,047–61,314,210, 164 basesExon 13: 61,314,308–61,314,486, 179 basesExon 12: 61,316,285–61,316,393, 109 basesExon 11: 61,316,492–61,316,567, 76 basesExon 10: 61,321,595–61,321,697, 103 basesExon 9: 61,322,296–61,322,412, 117 basesExon 8: 61,323,011–61,323,094, 84 basesExon 7: 61,323,979–61,324,137, 159 basesExon 6: 61,325,611–61,325,708, 98 basesExon 5: 61,326,779–61,326,893, 115 basesExon 4: 61,329,363–61,329,584, 222 basesExon 3: 61,329,958–61,330,074, 117 basesExon 2: 61,331,543–61,331,691, 149 basesExon 1: 61,332,908–61,333,105, 198 bases2725201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.2 kb of the gene's 33.7 kb; 3,423 of those bases code for the protein.

How a genome test reads DDB1

2

positions in DDB1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 33.7 kb of DDB1, introns included, not only the 4.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DDB1 gene: damage specific DNA binding protein 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/ddb1

Vancouver

Dante Labs. DDB1 gene: damage specific DNA binding protein 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ddb1

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