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Gene

CUL7

cullin 7

Summary

Cytogenetic location
6p21.1
Coordinates
Chromosome 6: 43,037,617–43,053,851 (GRCh38)
Exons
26 exons across 16.2 kb
Protein
1,698 amino acids
Also known as
dJ20C7.5
Previous symbols
KIAA0076
MANE Select transcript
ENST00000265348.9NM_014780.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CUL7 yet. The test sequences your whole genome, so your data includes it all the same.

How CUL7 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 6, with a bracket where CUL7 sits. CUL7 and 32 genes near it on chromosome 6, from 42,545,734 to 43,545,733.Chromosome 66p21.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2742.6 Mb42.8 Mb43 Mb43.2 Mb43.4 MbUBR2: 42,563,969–42,693,505, forward strandUBR2PRPH2: 42,696,598–42,722,621, reverse strandPRPH2TBCC: 42,744,498–42,746,103, reverse strandTBCCBICRAL: 42,781,931–42,868,560, forward strandBICRALRPL7L1: 42,879,602–42,889,925, forward strandRPL7L1PEX39: 42,890,265–42,890,821, reverse strandPEX39PTCRA: 42,915,989–42,925,845, forward strandPTCRACNPY3: 42,928,975–42,940,217, forward strandCNPY3PEX6: 42,959,717–42,979,249, reverse strandPEX6GNMT: 42,960,268–42,970,699, forward strandGNMTPPP2R5D: 42,984,533–43,012,346, forward strandPPP2R5DMEA1: 43,011,143–43,016,868, reverse strandKLHDC3: 43,014,103–43,021,314, forward strandRRP36: 43,021,588–43,034,156, forward strandCUL7: 43,037,617–43,053,851, reverse strandCUL7KLC4: 43,040,777–43,075,099, forward strandKLC4: 43,051,066–43,058,185, reverse strandMRPL2: 43,054,029–43,059,464, reverse strandMRPL2PTK7: 43,076,256–43,161,719, forward strandPTK7SRF: 43,170,910–43,181,506, forward strandSRFCUL9: 43,182,166–43,224,587, forward strandCUL9DNPH1: 43,225,629–43,229,490, reverse strandDNPH1TTBK1: 43,243,481–43,288,258, forward strandTTBK1SLC22A7: 43,295,694–43,305,543, forward strandSLC22A7CRIP3: 43,299,710–43,308,878, reverse strandCRIP3ZNF318: 43,307,134–43,369,687, reverse strandZNF318ABCC10: 43,427,366–43,451,783, forward strandABCC10DLK2: 43,450,351–43,456,632, reverse strandDLK2TJAP1: 43,477,523–43,506,562, forward strandTJAP1LRRC73: 43,506,062–43,510,388, reverse strandLRRC73POLR1C: 43,509,702–43,562,419, forward strandPOLR1CYIPF3: 43,511,200–43,516,985, reverse strandYIPF3XPO5: 43,522,334–43,576,091, reverse strandDiagram of CUL7: 26 exons on the reverse strand of chromosome 6Exon 25: 2 known disease-causing sitesExon 24: 1 known disease-causing siteExon 23: 7 known disease-causing sitesExon 22: 2 known disease-causing sitesExon 21: 3 known disease-causing sitesExon 20: 1 known disease-causing siteExon 19: 1 known disease-causing siteExon 18: 1 known disease-causing siteExon 17: 2 known disease-causing sitesExon 16: 5 known disease-causing sitesExon 15: 2 known disease-causing sitesExon 14: 2 known disease-causing sitesExon 13: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 10: 2 known disease-causing sitesExon 9: 4 known disease-causing sitesExon 8: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 6: 2 known disease-causing sitesExon 4: 3 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 2: 5 known disease-causing sitesExon 26: 43,037,617–43,038,011, 395 basesExon 25: 43,038,267–43,038,472, 206 basesExon 24: 43,038,566–43,038,692, 127 basesExon 23: 43,038,842–43,038,987, 146 basesExon 22: 43,040,156–43,040,426, 271 basesExon 21: 43,040,530–43,040,746, 217 basesExon 20: 43,040,915–43,041,075, 161 basesExon 19: 43,042,802–43,042,984, 183 basesExon 18: 43,043,074–43,043,180, 107 basesExon 17: 43,043,448–43,043,630, 183 basesExon 16: 43,044,752–43,044,885, 134 basesExon 15: 43,045,227–43,045,402, 176 basesExon 14: 43,045,587–43,045,682, 96 basesExon 13: 43,045,986–43,046,091, 106 basesExon 12: 43,046,236–43,046,407, 172 basesExon 11: 43,046,511–43,046,601, 91 basesExon 10: 43,046,880–43,047,107, 228 basesExon 9: 43,048,148–43,048,253, 106 basesExon 8: 43,048,332–43,048,569, 238 basesExon 7: 43,049,407–43,049,662, 256 basesExon 6: 43,049,963–43,050,159, 197 basesExon 5: 43,050,260–43,050,398, 139 basesExon 4: 43,050,968–43,051,468, 501 basesExon 3: 43,051,612–43,051,763, 152 basesExon 2: 43,052,209–43,052,796, 588 basesExon 1: 43,053,622–43,053,851, 230 bases262422201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.4 kb of the gene's 16.2 kb; 5,097 of those bases code for the protein.

How a genome test reads CUL7

68

positions in CUL7 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 16.2 kb of CUL7, introns included, not only the 5.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CUL7 gene: cullin 7. Retrieved 16 October 2026, from https://dantelabs.com/genes/cul7

Vancouver

Dante Labs. CUL7 gene: cullin 7 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/cul7

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