Gene
CDH11
cadherin 11
- HGNC 1750↗(opens in a new tab)
- Ensembl gene ENSG00000140937↗(opens in a new tab)
- NCBI Gene 1009↗(opens in a new tab)
Summary
- Cytogenetic location
- 16q21
- Coordinates
- Chromosome 16: 64,943,753–65,122,063 (GRCh38)
- Exons
- 13 exons across 178.3 kb
- Protein
- 796 amino acids
- Also known as
- OB, CAD11
- MANE Select transcript
- ENST00000268603.9NM_001797.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read CDH11, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads CDH11 yet. The test sequences your whole genome, so your data includes it all the same.
How CDH11 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 6.7 kb of the gene's 178.3 kb; 2,391 of those bases code for the protein.
How a genome test reads CDH11
2
positions in CDH11 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 178.3 kb of CDH11, introns included, not only the 6.7 kb of exons.
Traits linked to CDH11
The Human Phenotype Ontology lists these as features of the rare conditions CDH11 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Absence of front tooth
- Bad bite
- Big lower jaw
- Broad philtrum
- Bulbous nose
- Delayed eruption of teeth
- High palate
- Multiple impacted teeth
Show 56 more traits
- Nasal tip, upturned
- Pointed chin
- Premature glabellar skin wrinkling
- Thick eyebrow
- Thin red part of the upper lip
- Wide nasal bridge
- Wide nose
- Abnormal dentin
- Abnormal dentition
- Abnormal sella turcica morphology
- Abnormality of the midface
- Abnormally small head
- Advanced pneumatization of the mastoid process
- Bifid uvula
- Blepharochalasis
- Broad head shape
- Broad nasal tip
- Chin with horizontal crease
- Corners of eye widely separated
- Decreased size of maxilla
- Dental cavities
- Depressed nasal bridge
- Downturned corners of mouth
- Flat face
- High forehead
- Highly arched eyebrow
- Increased thickness of skull cap
- Monobrow
- One sided cleft palate
- Rootless teeth
- Short neck
- Submucous cleft hard palate
- Wrinkles around the eyes
- Broad forehead
- Cleft nasal tip
- Decreased volume of lip
- Deformity of the skull
- Downward slanting of the opening between the eyelids
- Drooping lower lip
- Early tooth loss
- Extra teeth
- Impacted tooth
- Short nose
- Short philtrum
- Wider-than-typical soft spot of skull
- Zygomatic flattening
- Cleft eyelid
- Cleft palate
- Cleft upper eyelid
- Decreased size of tooth
- Facial asymmetry
- Full lower lip
- Long philtrum
- Low hanging columella
- Midface retrusion
- Narrow forehead
Abnormality of the eye
- Bulging eye
- Wide-set eyes
- Cross-eyed
- Clouding of the lens of the eye
- Enlarged cornea
- Exodeviation
- Glaucoma
- Increased cup-to-disc ratio
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). CDH11 gene: cadherin 11. Retrieved 16 October 2026, from https://dantelabs.com/genes/cdh11
Dante Labs. CDH11 gene: cadherin 11 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/cdh11
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks