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Gene

MN1

MN1 proto-oncogene, transcriptional regulator

Summary

Cytogenetic location
22q12.1
Coordinates
Chromosome 22: 27,748,277–27,801,756 (GRCh38)
Exons
2 exons across 53.5 kb
Protein
1,320 amino acids
Also known as
MGCR1-PEN, MGCR1
Previous symbols
MGCR
MANE Select transcript
ENST00000302326.5NM_002430.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MN1 yet. The test sequences your whole genome, so your data includes it all the same.

How MN1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 22, with a bracket where MN1 sits. MN1 and 2 genes near it on chromosome 22, from 27,275,017 to 28,275,016.Chromosome 2222q12.1p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3327.4 Mb27.6 Mb27.8 Mb28 Mb28.2 MbMN1: 27,748,277–27,801,756, reverse strandMN1PITPNB: 27,851,423–27,920,134, reverse strandPITPNBTTC28: 27,978,014–28,679,925, reverse strandTTC28Diagram of MN1: 2 exons on the reverse strand of chromosome 22Exon 2: 7 known disease-causing sitesExon 1: 12 known disease-causing sitesExon 2: 27,748,277–27,751,096, 2,820 basesExon 1: 27,796,763–27,801,756, 4,994 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.8 kb of the gene's 53.5 kb; 3,963 of those bases code for the protein.

How a genome test reads MN1

19

positions in MN1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 53.5 kb of MN1, introns included, not only the 7.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MN1 gene: MN1 proto-oncogene, transcriptional regulator. Retrieved 16 October 2026, from https://dantelabs.com/genes/mn1

Vancouver

Dante Labs. MN1 gene: MN1 proto-oncogene, transcriptional regulator [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/mn1

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