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Gene

KCNJ8

potassium inwardly rectifying channel subfamily J member 8

Summary

Cytogenetic location
12p12.1
Coordinates
Chromosome 12: 21,764,955–21,774,706 (GRCh38)
Exons
3 exons across 9.8 kb
Protein
424 amino acids
Also known as
Kir6.1
MANE Select transcript
ENST00000240662.3NM_004982.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KCNJ8 yet. The test sequences your whole genome, so your data includes it all the same.

How KCNJ8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 12, with a bracket where KCNJ8 sits. KCNJ8 and 13 genes near it on chromosome 12, from 21,269,831 to 22,269,830.Chromosome 1212p12.1p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3321.4 Mb21.6 Mb21.8 Mb22 Mb22.2 MbSLCO1B1: 21,127,862–21,298,065, forward strandSLCO1B1SLCO1A2: 21,264,600–21,419,676, reverse strandSLCO1A2IAPP: 21,354,959–21,379,980, forward strandIAPPPYROXD1: 21,437,591–21,471,250, forward strandPYROXD1RECQL: 21,464,720–21,501,669, reverse strandRECQLGOLT1B: 21,501,781–21,518,408, forward strandGOLT1BSPX: 21,526,296–21,541,249, forward strandSPXGYS2: 21,531,545–21,604,951, reverse strandGYS2: 21,536,203–21,657,798, reverse strandLDHB: 21,635,339–21,757,890, reverse strandLDHBKCNJ8: 21,764,955–21,774,706, reverse strandKCNJ8ABCC9: 21,797,389–21,942,543, reverse strandABCC9CMAS: 22,046,174–22,065,674, forward strandCMASST8SIA1: 22,063,773–22,437,041, reverse strandST8SIA1Diagram of KCNJ8: 3 exons on the reverse strand of chromosome 12Exon 3: 1 known disease-causing siteExon 3: 21,764,955–21,766,623, 1,669 basesExon 2: 21,773,243–21,773,686, 444 basesExon 1: 21,774,546–21,774,706, 161 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.3 kb of the gene's 9.8 kb; 1,275 of those bases code for the protein.

How a genome test reads KCNJ8

1

position in KCNJ8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.8 kb of KCNJ8, introns included, not only the 2.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KCNJ8 gene: potassium inwardly rectifying channel subfamily J member 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/kcnj8

Vancouver

Dante Labs. KCNJ8 gene: potassium inwardly rectifying channel subfamily J member 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kcnj8

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